An automated, handheld biosensor for aflatoxin

An automated, handheld biosensor for aflatoxin

A new immunoaffinity fluorometric biosensor has been developed for detecting and quantifying aflatoxins, a family of potent fungi-produced carcinogens that are commonly found in a variety of agriculture products. They have also been cited as a biological agent under weapons development. The handheld...

Full description

Saved in:
Bibliographic Details
Published in:Biosensors & bioelectronics Vol. 14; no. 10; pp. 841 - 848
Main Authors: Carlson, M.A., Bargeron, C.B., Benson, R.C., Fraser, A.B., Phillips, T.E., Velky, J.T., Groopman, J.D., Strickland, P.T., Ko, H.W.
Format: Journal Article
Language:English
Published: England Elsevier B.V 2000
Subjects:
Aflatoxin
Aflatoxins - analysis
Automated
biological warfare
biological warfare agents
Biosensing Techniques
Biosensor
Fluorescence
Fluorescent Antibody Technique
Handheld
Immunoaffinity
Immunoassay
Fluorescence
Automated
Handheld
Immunoaffinity
Biosensor
Aflatoxin
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A new immunoaffinity fluorometric biosensor has been developed for detecting and quantifying aflatoxins, a family of potent fungi-produced carcinogens that are commonly found in a variety of agriculture products. They have also been cited as a biological agent under weapons development. The handheld, self-contained biosensor is fully automatic, highly sensitive, quick, quantitative, and requires no special storage. Approximately 100 measurements can be made before refurbishment is required, and concentrations from 0.1 parts per billion (ppb) to 50 ppb can be determined in <2 min with a 1 ml sample volume. The device operates on the principles of immunoaffinity for specificity and fluorescence for a quantitative assay. The analytic procedure is flexible so that other chemical and biological analytes could be detected with minor modifications to the current device. Advances in electro-optical components, electronics, and miniaturized fluidics were combined to produce this reliable, small, and versatile instrument.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0956-5663
1873-4235
DOI:10.1016/S0956-5663(99)00057-3