Search Results - "Velinova, M"
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Structure and aggregation proclivity of C12E3 in aqueous solution
Published in Chemical physics (02-01-2013)“…[Display omitted] ► Dodecyl(triethylene glycol) and its dimers are modeled by DFT and ONIOM in water. ► Single molecules and dimers are very flexible and allow…”
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Lymphatic uptake and biodistribution of liposomes after subcutaneous injection: IV. Fate of liposomes in regional lymph nodes
Published in Biochimica et biophysica acta (13-03-1998)“…The ability of clodronate-containing liposomes to deplete lymph nodes of macrophages was used as a tool to investigate the fate of liposomes in regional lymph…”
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Uptake of Long-Circulating Immunoliposomes, Directed Against Colon Adenocarcinoma Cells, by Liver Metastases of Colon Cancer
Published in Journal of drug targeting (2000)“…AbstractRadiolabeled ([3H]cholesteryloleyl ether) immunoliposomes directed against rat colon adenocarcinoma CC531 cells were prepared by random coupling of a…”
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Abstract P3-14-10: Proposed biosimilar pegfilgrastim LA-EP2006 shows similarity in pharmacokinetics and pharmacodynamics to reference pegfilgrastim in healthy subjects
Published in Cancer research (Chicago, Ill.) (15-02-2018)“…Abstract Background: Granulocyte colony-stimulating factors such as filgrastim and its long-acting version pegfilgrastim are widely used to prevent neutropenia…”
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Different intrahepatic distribution of phosphatidylglycerol and phosphatidylserine liposomes in the rat
Published in Hepatology (Baltimore, Md.) (01-08-1997)“…Liposomes with diameters of 200 to 400 nm containing phosphatidylserine (PS) or phosphatidylglycerol (PG) were injected intravenously into rats. Two hours…”
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New histochemical and ultrastructural observations on normal bovine tonsils
Published in Veterinary record (17-11-2001)“…Samples of normal bovine palatine tonsils were examined by light and electron microscopy. Like human tonsils, they were composed of crypts, subepithelial…”
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Journal Article Web Resource -
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Selective transfer of a lipophilic prodrug of 5-fluorodeoxyuridine from immunoliposomes to colon cancer cells
Published in Biochimica et biophysica acta (20-08-1999)“…A monoclonal antibody against the rat colon carcinoma CC531 was covalently coupled to liposomes containing a dipalmitoylated derivative of the anticancer drug…”
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1815PRandomized, double-blind, cross-over phase I study comparing pharmacokinetics, pharmacodynamics, safety and immunogenicity of a biosimilar pegfilgrastim with EU and US references
Published in Annals of oncology (01-10-2019)“…Abstract Background The pharmacokinetic (PK)/pharmacodynamic (PD), safety and immunogenicity profiles of Sandoz biosimilar pegfilgrastim (Ziextenzo®) and EU…”
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1815P - Randomized, double-blind, cross-over phase I study comparing pharmacokinetics, pharmacodynamics, safety and immunogenicity of a biosimilar pegfilgrastim with EU and US references
Published in Annals of oncology (01-10-2019)“…The pharmacokinetic (PK)/pharmacodynamic (PD), safety and immunogenicity profiles of Sandoz biosimilar pegfilgrastim (Ziextenzo®) and EU reference…”
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Comparison of the Pharmacokinetics, Safety, and Tolerability of the Autoinjector (AI) and Pre-Filled Syringe (PFS) of SB4 in Healthy Subjects
Published in Drug design, development and therapy (01-01-2020)“…SB4 is an etanercept biosimilar, approved by the European Commission (EC) and the US Food and Drug Administration (FDA) following a demonstration of equivalent…”
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Pharmacokinetics, metabolism and safety of deuterated L‐DOPA (SD‐1077)/carbidopa compared to L‐DOPA/carbidopa following single oral dose administration in healthy subjects
Published in British journal of clinical pharmacology (01-10-2018)“…Aims SD‐1077, a selectively deuterated precursor of dopamine (DA) structurally related to L‐3,4‐dihydroxyphenylalanine (L‐DOPA), is under development for…”
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Lymphatic uptake and biodistribution of liposomes after subcutaneous injection
Published in Biochimica et biophysica acta. Biomembranes (01-03-1998)Get full text
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A phase 1 randomized study evaluating the effect of omeprazole on the pharmacokinetics of a novel 5-hydroxytryptamine receptor 4 agonist, revexepride (SSP-002358), in healthy adults
Published in Drug design, development and therapy (01-01-2015)“…About 30% of patients with gastroesophageal reflux disease continue to experience symptoms despite treatment with proton pump inhibitors. The…”
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Ultrastructural Analysis of DNA Complexes During Transfection and Intracellular Transport
Published in The journal of histochemistry and cytochemistry (01-09-2003)“…We present a simple method based on transmission electron microscopy that allows investigation of the early steps of polyplex-mediated transfection without the…”
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Nanocapsules: lipid-coated aggregates of cisplatin with high cytotoxicity
Published in Nature medicine (01-01-2002)“…Cisplatin is one of the most widely used agents in the treatment of solid tumors, but its clinical utility is limited by toxicity. The development of less…”
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Modulation of pharmacokinetic behavior of liposomes
Published in Advanced drug delivery reviews (17-03-1997)“…The authors's recent work on matters pertinent to the in vivo processing of systemically administered liposomes is reviewed. Particular emphasis is given to…”
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Morphological observations on the fate of liposomes in the regional lymph nodes after footpad injection into rats
Published in Biochimica et biophysica acta (19-01-1996)“…Multilamellar liposomes composed of equimolar egg phosphatidylcholine and cholesterol and containing carboxyfluorescein or colloidal gold were injected…”
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Preparation and stability of lipid-coated nanocapsules of cisplatin: anionic phospholipid specificity
Published in Biochimica et biophysica acta (27-05-2004)“…Cisplatin nanocapsules represent a novel lipid formulation of the anti-cancer drug cis-diamminedichloroplatinum(II) (cisplatin), in which nanoprecipitates of…”
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