Search Results - "Velic, Ana"

Initial Quantitative Proteomic Map of 28 Mouse Tissues Using the SILAC Mouse by Geiger, Tamar, Velic, Ana, Macek, Boris, Lundberg, Emma, Kampf, Caroline, Nagaraj, Nagarjuna, Uhlen, Mathias, Cox, Juergen, Mann, Matthias

“…Identifying the building blocks of mammalian tissues is a precondition for understanding their function. In particular, global and quantitative analysis of the…”
Get full text

Regulation of the opposing (p)ppGpp synthetase and hydrolase activities in a bifunctional RelA/SpoT homologue from Staphylococcus aureus by Gratani, Fabio Lino, Horvatek, Petra, Geiger, Tobias, Borisova, Marina, Mayer, Christoph, Grin, Iwan, Wagner, Samuel, Steinchen, Wieland, Bange, Gert, Velic, Ana, Maček, Boris, Wolz, Christiane

“…The stringent response is characterized by (p)ppGpp synthesis resulting in repression of translation and reprogramming of the transcriptome. In Staphylococcus…”
Get full text

Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma by Löffler, Markus W, Mohr, Christopher, Bichmann, Leon, Freudenmann, Lena Katharina, Walzer, Mathias, Schroeder, Christopher M, Trautwein, Nico, Hilke, Franz J, Zinser, Raphael S, Mühlenbruch, Lena, Kowalewski, Daniel J, Schuster, Heiko, Sturm, Marc, Matthes, Jakob, Riess, Olaf, Czemmel, Stefan, Nahnsen, Sven, Königsrainer, Ingmar, Thiel, Karolin, Nadalin, Silvio, Beckert, Stefan, Bösmüller, Hans, Fend, Falko, Velic, Ana, Maček, Boris, Haen, Sebastian P, Buonaguro, Luigi, Kohlbacher, Oliver, Stevanović, Stefan, Königsrainer, Alfred, Rammensee, Hans-Georg

“…Although mutated HLA ligands are considered ideal cancer-specific immunotherapy targets, evidence for their presentation is lacking in hepatocellular…”
Get full text

Mechanisms of angiotensin II signaling on cytoskeleton of podocytes by Hsu, Hsiang-Hao, Hoffmann, Sigrid, Endlich, Nicole, Velic, Ana, Schwab, Albrecht, Weide, Thomas, Schlatter, Eberhard, Pavenstädt, Hermann

“…Podocytes are significant in establishing the glomerular filtration barrier. Sustained rennin–angiotensin system (RAS) activation is crucial in the…”
Get full text

Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells by Thomas, Katharina, Zondler, Lisa, Ludwig, Nadine, Kardell, Marina, Lüneburg, Corinna, Henke, Katharina, Mersmann, Sina, Margraf, Andreas, Spieker, Tilmann, Tekath, Tobias, Velic, Ana, Holtmeier, Richard, Hermann, Juliane, Jankowski, Vera, Meersch, Melanie, Vestweber, Dietmar, Westphal, Martin, Roth, Johannes, Schäfers, Michael A, Kellum, John A, Lowell, Clifford A, Rossaint, Jan, Zarbock, Alexander

“…Acute kidney injury (AKI) represents a common complication in critically ill patients that is associated with increased morbidity and mortality. In a murine…”
Get full text

Human Leucocyte Antigen G and Murine Qa-2 Are Critical for Myeloid Derived Suppressor Cell Expansion and Activation and for Successful Pregnancy Outcome by Dietz, Stefanie, Schwarz, Julian, Velic, Ana, González-Menéndez, Irene, Quintanilla-Martinez, Leticia, Casadei, Nicolas, Marmé, Alexander, Poets, Christian F, Gille, Christian, Köstlin-Gille, Natascha

“…During pregnancy, maternal immune system has to balance tightly between protection against pathogens and tolerance towards a semi-allogeneic organism…”
Get full text

Implications of specific lysine residues within ataxin-3 for the molecular pathogenesis of Machado-Joseph disease by Pereira Sena, Priscila, Weber, Jonasz Jeremiasz, Bayezit, Sercan, Saup, Rafael, Incebacak Eltemur, Rana Dilara, Li, Xiaoling, Velic, Ana, Jung, Jaqueline, Macek, Boris, Nguyen, Huu Phuc, Riess, Olaf, Schmidt, Thorsten

“…Lysine residues are one of the main sites for posttranslational modifications of proteins, and lysine ubiquitination of the Machado-Joseph disease protein…”
Get full text

The Calcium-Sensing Receptor Promotes Urinary Acidification to Prevent Nephrolithiasis by RENKEMA, Kirsten Y, VELIC, Ana, HOENDEROP, Joost G, DIJKMAN, Henry B, VERKAART, Sjoerd, VAN DER KEMP, Annemiete W, NOWIK, Marta, TIMMERMANS, Kim, DOUCET, Alain, WAGNER, Carsten A, BINDELS, René J

“…Hypercalciuria increases the risk for urolithiasis, but renal adaptive mechanisms reduce this risk. For example, transient receptor potential vanilloid 5…”
Get full text

Efficient reduction of synthetic mRNA induced immune activation by simultaneous delivery of B18R encoding mRNA by Michel, Tatjana, Golombek, Sonia, Steinle, Heidrun, Hann, Ludmilla, Velic, Ana, Macek, Boris, Krajewski, Stefanie, Schlensak, Christian, Wendel, Hans Peter, Avci-Adali, Meltem

“…The application of synthetic modified messenger RNA (mRNA) is a promising approach for the treatment of a variety of diseases and vaccination. In the past few…”
Get full text

A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib by Sinnberg, Tobias, Makino, Elena, Krueger, Marcel A., Velic, Ana, Macek, Boris, Rothbauer, Ulrich, Groll, Nicola, Pötz, Oliver, Czemmel, Stefan, Niessner, Heike, Meier, Friedegund, Ikenberg, Kristian, Garbe, Claus, Schittek, Birgit

“…Acquired resistance to second generation BRAF inhibitors (BRAFis), like vemurafenib is limiting the benefits of long term targeted therapy for patients with…”
Get full text

Staphylococcal Enterotoxins Dose-Dependently Modulate the Generation of Myeloid-Derived Suppressor Cells by Stoll, Hartmut, Ost, Michael, Singh, Anurag, Mehling, Roman, Neri, Davide, Schäfer, Iris, Velic, Ana, Macek, Boris, Kretschmer, Dorothee, Weidenmaier, Christopher, Hector, Andreas, Handgretinger, Rupert, Götz, Friedrich, Peschel, Andreas, Hartl, Dominik, Rieber, Nikolaus

“…is one of the major human bacterial pathogens causing a broad spectrum of serious infections. Myeloid-derived suppressor cells (MDSC) represent an innate…”
Get full text

Angiotensin II stimulates vacuolar H+-ATPase activity in renal acid-secretory intercalated cells from the outer medullary collecting duct by ROTHENBERGER, Florina, VELIC, Ana, STEHBERGER, Paul A, KOVACIKOVA, Jana, WAGNER, Carsten A

“…Final urinary acidification is mediated by the action of vacuolar H(+)-ATPases expressed in acid-secretory type A intercalated cells (A-IC) in the collecting…”
Get full text

Comparative Transcriptional Profiling of Motor Neuron Disorder-Associated Genes in Various Human Cell Culture Models by Hauser, Stefan, Schuster, Stefanie, Heuten, Elena, Höflinger, Philip, Admard, Jakob, Schelling, Yvonne, Velic, Ana, Macek, Boris, Ossowski, Stephan, Schöls, Ludger

“…Disease modeling requires appropriate cellular models that best mimic the underlying pathophysiology. Human origin and an adequate expression of the disease…”
Get full text

The Proton-activated G Protein Coupled Receptor OGR1 Acutely Regulates the Activity of Epithelial Proton Transport Proteins by Mohebbi, Nilufar, Benabbas, Chahira, Vidal, Solange, Daryadel, Arezoo, Bourgeois, Soline, Velic, Ana, Ludwig, Marie-Gabrielle, Seuwen, Klaus, Wagner, Carsten A.

“…The Ovarian cancer G protein-coupled Receptor 1 (OGR1; GPR68) is proton-sensitive in the pH range of 6.8 - 7.8. However, its physiological function is not…”
Get full text

Genome-wide gene expression profiling reveals renal genes regulated during metabolic acidosis by Nowik, Marta, Lecca, M. Rita, Velic, Ana, Rehrauer, Hubert, Brandli, Andre W, Wagner, Carsten A

“…1 Institute of Physiology and Zurich Center for Human Integrative Physiology (ZIHP), University of Zurich 2 Institute of Pharmaceutical Sciences, Department of…”
Get full text

Enhanced activity of the myocardial Na+/H+ exchanger NHE-1 contributes to cardiac remodeling in atrial natriuretic peptide receptor-deficient mice by KILIC, Ana, VELIC, Ana, KUHN, Michaela, DE WINDT, Leon J, FABRITZ, Larissa, VOSS, Melanie, MITKO, Danuta, ZWIENER, Melanie, BABA, Hideo A, VAN EICKELS, Martin, SCHLATTER, Eberhard

“…Atrial natriuretic peptide (ANP), through its guanylyl cyclase-A (GC-A) receptor, not only is critically involved in the endocrine regulation of arterial blood…”
Get full text

The Proton-Activated Receptor GPR4 Modulates Glucose Homeostasis by Increasing Insulin Sensitivity by Giudici, Luca, Velic, Ana, Daryadel, Arezoo, Bettoni, Carla, Mohebbi, Nilufar, Suply, Thomas, Seuwen, Klaus, Ludwig, Marie-Gabrielle, Wagner, Carsten A.

“…Background: The proton-activated G protein-coupled receptor GPR4 is expressed in many tissues including white adipose tissue. GPR4 is activated by…”
Get full text

Toward Quantitative Proteomics of Organ Substructures: Implications for Renal Physiology by Velic, Ana, PhD, Macek, Boris, PhD, Wagner, Carsten A., MD

“…Summary Organs are complex structures that consist of multiple tissues with different levels of gene expression. To achieve comprehensive coverage and accurate…”
Get full text

Regulation of human organic cation transporter hOCT2 by PKA, PI3K, and calmodulin-dependent kinases by Cetinkaya, Ibrahim, Ciarimboli, Giuliano, Yalçinkaya, Gülay, Mehrens, Thomas, Velic, Ana, Hirsch, Jochen R, Gorboulev, Valentin, Koepsell, Hermann, Schlatter, Eberhard

“…Properties and regulation of the human organic cation (OC) transporter type 2 (hOCT2) expressed in HEK-293 cells were extensively characterized using the…”
Get more information

SPRTN-dependent DPC degradation precedes repair of damaged DNA: a proof of concept revealed by the STAR assay by Glumac, Mateo, Polović, Mirjana, Batel, Anja, Gelemanović, Andrea, Maček, Boris, Velić, Ana, Marinović-Terzić, Ivana

“…Abstract DNA-protein crosslinks (DPCs), formed by the covalent conjugation of proteins to DNA, are toxic lesions that interfere with DNA metabolic processing…”
Get full text