Search Results - "Veldic, M"

The Role of Base Excision Repair in Major Depressive Disorder and Bipolar Disorder by Kucuker, M., Ozerdem, A., Ceylan, D., Cabello-Arreola, A., Ho, M.C., Joseph, B., Webb, L., Croarkin, P., Frye, M., Veldic, M.

“…Introduction In vivo and in vitro studies suggest that inflammation and oxidative damage may contribute to the pathogenesis of major depressive disorder (MDD)…”
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The Benzamide MS-275 Is a Potent, Long-Lasting Brain Region-Selective Inhibitor of Histone Deacetylases by Simonini, M. V., Camargo, L. M., Dong, E., Maloku, E., Veldic, M., Costa, E., Guidotti, A.

“…The association of the histone deacetylase (HDAC) inhibitor valproate (VPA) with atypical antipsychotics has become a frequent treatment strategy for…”
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Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection by RUZICKA, W. B, ZHUBI, A, VELDIC, M, GRAYSON, D. R, COSTA, E, GUIDOTTI, A

“…Among the most consistent results of studies of post-mortem brain tissue from schizophrenia patients (SZP) is the finding that in this disease, several genes…”
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Feasibility of investigating differential proteomic expression in depression: implications for biomarker development in mood disorders by Frye, M A, Nassan, M, Jenkins, G D, Kung, S, Veldic, M, Palmer, B A, Feeder, S E, Tye, S J, Choi, D S, Biernacka, J M

“…The objective of this study was to determine whether proteomic profiling in serum samples can be utilized in identifying and differentiating mood disorders. A…”
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An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes by Zhubi, A, Veldic, M, Puri, N.V, Kadriu, B, Caruncho, H, Loza, I, Sershen, H, Lajtha, A, Smith, R.C, Guidotti, A, Davis, J.M, Costa, E

“…Abstract Several lines of schizophrenia (SZ) research suggest that a functional downregulation of the prefrontal cortex GABAergic neuronal system is mediated…”
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DNA-Methyltransferase 1 mRNA Is Selectively Overexpressed in Telencephalic GABAergic Interneurons of Schizophrenia Brains by Veldic, M., Caruncho, H. J., Liu, W. S., Davis, J., Satta, R., Grayson, D. R., Guidotti, A., Costa, E.

“…A down-regulation of reelin and glutamic acid decarboxylase (GAD) 67 mRNAs was detected in γ-aminobutyric acid (GABA)ergic cortical interneurons of…”
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Genome-wide DNA methylomic differences between dorsolateral prefrontal and temporal pole cortices of bipolar disorder by Ho, Ada M.-C., Winham, Stacey J., Armasu, Sebastian M., Blacker, Caren J., Millischer, Vincent, Lavebratt, Catharina, Overholser, James C., Jurjus, George J., Dieter, Lesa, Mahajan, Gouri, Rajkowska, Grazyna, Vallender, Eric J., Stockmeier, Craig A., Robertson, Keith D., Frye, Mark A., Choi, Doo-Sup, Veldic, Marin

“…Dorsolateral prefrontal cortex (DLPFC) and temporal pole (TP) are brain regions that display abnormalities in bipolar disorder (BD) patients. DNA methylation —…”
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A GABAergic cortical deficit dominates schizophrenia pathophysiology by Costa, E, Davis, J M, Dong, E, Grayson, D R, Guidotti, A, Tremolizzo, L, Veldic, M

“…Several lines of evidence support the role of an epigenetic-induced GABAergic cortical dysfunction in schizophrenia psychopathology, which is probably…”
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REELIN and schizophrenia: a disease at the interface of the genome and the epigenome by Costa, E, Chen, Y, Davis, J, Dong, E, Noh, J S, Tremolizzo, L, Veldic, M, Grayson, D R, Guidotti, A

“…The downregulation of the Reelin gene (RELN) that occurs in schizophrenic brains, which are characterized by pyramidal neurons with shortened dendrites and by…”
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Nicotinic cholinergic mechanisms in the regulation of brain DNA-methyltransferase 1 (DNMT1) expression by Maloku, E, Satta, R, Zhubi, A, Veldic, M, Kadriu, B, Guidotti, A, Costa, E

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Neurochemical basis for an epigenetic vision of synaptic organization by Costa, E, Grayson, D R, Veldic, M, Guidotti, A

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Epigenetic targets in GABAergic neurons to treat schizophrenia by Costa, E, Dong, E, Grayson, D R, Ruzicka, W B, Simonini, M V, Veldic, M, Guidotti, A

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Methylation of Brain Derived Neurotrophic Factor (BDNF) Val66Met CpG site is associated with early onset bipolar disorder by Nassan, Malik, Veldic, Marin, Winham, Stacey, Frye, Mark A., Larrabee, Beth, Colby, Colin, Biernacka, Joanna, Bellia, Fabio, Pucci, Mariangela, Terenius, Lars, Vukojevic, Vladana, D´Addario, Claudio

“…The brain-derived neurotrophic factor (BDNF) rs6265 (Val66Met) Met allele is associated with early onset (≤ 19 years old) bipolar disorder (BD). Val66Met…”
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A Review of Epigenetics of PTSD in Comorbid Psychiatric Conditions by Blacker, Caren J, Frye, Mark A, Morava, Eva, Kozicz, Tamas, Veldic, Marin

“…Post-traumatic stress disorder (PTSD) is an acquired psychiatric disorder with functionally impairing physiological and psychological symptoms following a…”
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Characterisation of age and polarity at onset in bipolar disorder by Vreeker, Annabel, McQuillin, Andrew, Stahl, Eli A., Bigdeli, Tim B., Stein, Frederike, Pelin, Helena, Adams, Mark J., Adolfsson, Rolf, Adorjan, Kristina, Aminoff, Sofie R., Anderson-Schmidt, Heike, Andreassen, Ole A., Balaban, Ceylan, Bass, Nicholas, Baune, Bernhard T., Bengesser, Susanne, Berrettini, Wade H, Boks, Marco P., Bromet, Evelyn J., Brosch, Katharina, Budde, Monika, Cervantes, Pablo, Chillotti, Catina, Cichon, Sven, Clark, Scott R., Comes, Ashley L., Corvin, Aiden, Croarkin, Paul E., Degenhardt, Franziska, DePaulo, J. Raymond, Eissa, Mariam Al, Elvsåshagen, Torbjørn, Etain, Bruno, Fanous, Ayman H., Fellendorf, Frederike, Fiorentino, Alessia, Frye, Mark A., Fullerton, Janice M., Gill, Michael, Gordon-Smith, Katherine, Guzman-Parra, Jose, Hasler, Roland, Heilbronner, Maria, Jamain, Stephane, Jones, Ian, Kelsoe, John R., Kennedy, James L., Kircher, Tilo, Kirov, George, Kranz, Thorsten M., Lagerberg, Trine Vik, Landen, Mikael, Li, Qingqin S., Malaspina, Dolores, Manchia, Mirko, Mayoral, Fermin, McIntosh, Andrew M., Medeiros, Helena, Melle, Ingrid, Milanova, Vihra, Nöthen, Markus M., Opel, Nils, Ortiz, Abigail, Owen, Michael J., Pålsson, Erik, Pato, Carlos, Pato, Michele T., Pawlak, Joanna, Pfarr, Julia-Katharina, Pisanu, Claudia, Rapaport, Mark H, Reich-Erkelenz, Daniela, Reininghaus, Eva, Repple, Jonathan, Richard-Lepouriel, Hélène, Roberts, Gloria, Schmitt, Simon, Schofield, Peter R., Schubert, K. Oliver, Schulte, Eva C., Severino, Giovanni, Sharp, Sally, Slaney, Claire, Sobell, Janet L., Squassina, Alessio, Stopkova, Pavla, Turecki, Gustavo, Twarowska-Hauser, Joanna, Veldic, Marin, Vieta, Eduard, Vincent, John B., Xu, Wei, Zai, Clement C., Di Florio, Arianna, Smoller, Jordan W., Biernacka, Joanna M., Alda, Martin, Falkai, Peter, Schulze, Thomas G., Ophoff, Roel A.

“…Studying phenotypic and genetic characteristics of age at onset (AAO) and polarity at onset (PAO) in bipolar disorder can provide new insights into disease…”
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In Psychosis, Cortical Interneurons Overexpress DNA-Methyltransferase 1 by Veldic, Marin, Guidotti, Alessandro, Maloku, Ekrem, Davis, John M., Costa, Erminio

“…Cortical DNA-methyltransferase 1 (DNMT1) is preferentially expressed in interneurons secreting GABA where it very likely contributes to promoter CpG island…”
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GABAergic dysfunction in schizophrenia : new treatment strategies on the horizon by GUIDOTTI, Alessandro, AUTA, James, DAVIS, John M, ERBO DONG, GRAYSON, Dennis R, VELDIC, Marin, XIANQUAN ZHANG, COSTA, Erminio

“…Cortical gamma-aminobutyric acid (GABA)ergic neurons contribute to the orchestration of pyramidal neuron population firing as follows: (1) by releasing GABA on…”
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P.1.a.029 - Genetics of specific clinical phenotypes of bipolar disorder: a focus on mania with psychosis by Fuentes, M., Markota, M., Chauhan, M., McElroy, S., Kung, S., Veldic, M., Bobo, W., Prieto, M., Cuellar-Barboza, A., Colby, C., Rummans, T., Frye, M., Biernacka, J.

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Genetics of specific clinical phenotypes of bipolar disorder: a focus on mania with psychosis by Fuentes, M., Markota, M., Chauhan, M., McElroy, S., Kung, S., Veldic, M., Bobo, W., Prieto, M., Cuellar-Barboza, A., Colby, C., Rummans, T., Frye, M., Biernacka, J.

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S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis by Guidotti, Alessandro, Ruzicka, William, Grayson, Dennis R, Veldic, Marin, Pinna, Graziano, Davis, John M, Costa, Erminio

“…Prefrontal cortex (Brodmannʼs area 9) levels of the methyl donor S-adenosyl methionine were increased by about two-fold in schizophrenia and bipolar disorder…”
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