Search Results - "Veldić, M"
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The Role of Base Excision Repair in Major Depressive Disorder and Bipolar Disorder
Published in European psychiatry (01-06-2022)“…Introduction In vivo and in vitro studies suggest that inflammation and oxidative damage may contribute to the pathogenesis of major depressive disorder (MDD)…”
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The Benzamide MS-275 Is a Potent, Long-Lasting Brain Region-Selective Inhibitor of Histone Deacetylases
Published in Proceedings of the National Academy of Sciences - PNAS (31-01-2006)“…The association of the histone deacetylase (HDAC) inhibitor valproate (VPA) with atypical antipsychotics has become a frequent treatment strategy for…”
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Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection
Published in Molecular psychiatry (01-04-2007)“…Among the most consistent results of studies of post-mortem brain tissue from schizophrenia patients (SZP) is the finding that in this disease, several genes…”
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Feasibility of investigating differential proteomic expression in depression: implications for biomarker development in mood disorders
Published in Translational psychiatry (08-12-2015)“…The objective of this study was to determine whether proteomic profiling in serum samples can be utilized in identifying and differentiating mood disorders. A…”
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An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes
Published in Schizophrenia research (01-06-2009)“…Abstract Several lines of schizophrenia (SZ) research suggest that a functional downregulation of the prefrontal cortex GABAergic neuronal system is mediated…”
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DNA-Methyltransferase 1 mRNA Is Selectively Overexpressed in Telencephalic GABAergic Interneurons of Schizophrenia Brains
Published in Proceedings of the National Academy of Sciences - PNAS (06-01-2004)“…A down-regulation of reelin and glutamic acid decarboxylase (GAD) 67 mRNAs was detected in γ-aminobutyric acid (GABA)ergic cortical interneurons of…”
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Genome-wide DNA methylomic differences between dorsolateral prefrontal and temporal pole cortices of bipolar disorder
Published in Journal of psychiatric research (01-10-2019)“…Dorsolateral prefrontal cortex (DLPFC) and temporal pole (TP) are brain regions that display abnormalities in bipolar disorder (BD) patients. DNA methylation —…”
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A GABAergic cortical deficit dominates schizophrenia pathophysiology
Published in Critical reviews in neurobiology (2004)“…Several lines of evidence support the role of an epigenetic-induced GABAergic cortical dysfunction in schizophrenia psychopathology, which is probably…”
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REELIN and schizophrenia: a disease at the interface of the genome and the epigenome
Published in Molecular interventions (01-02-2002)“…The downregulation of the Reelin gene (RELN) that occurs in schizophrenic brains, which are characterized by pyramidal neurons with shortened dendrites and by…”
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Digital image analysis of silver-stained nucleolar organizer region--associated proteins in endometrial cytologic samples
Published in Analytical and quantitative cytology and histology (01-02-1999)“…Digital image analysis was applied to determine the number, area and size of silver-stained nucleolar organizer regions (AgNORs) in cytologic samples from…”
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Nicotinic cholinergic mechanisms in the regulation of brain DNA-methyltransferase 1 (DNMT1) expression
Published in European psychiatry (01-03-2007)Get full text
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Neurochemical basis for an epigenetic vision of synaptic organization
Published in International review of neurobiology (2004)Get more information
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Epigenetic targets in GABAergic neurons to treat schizophrenia
Published in Advances in pharmacology (1990) (2006)Get more information
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Methylation of Brain Derived Neurotrophic Factor (BDNF) Val66Met CpG site is associated with early onset bipolar disorder
Published in Journal of affective disorders (15-04-2020)“…The brain-derived neurotrophic factor (BDNF) rs6265 (Val66Met) Met allele is associated with early onset (≤ 19 years old) bipolar disorder (BD). Val66Met…”
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A Review of Epigenetics of PTSD in Comorbid Psychiatric Conditions
Published in Genes (13-02-2019)“…Post-traumatic stress disorder (PTSD) is an acquired psychiatric disorder with functionally impairing physiological and psychological symptoms following a…”
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Characterisation of age and polarity at onset in bipolar disorder
Published in British journal of psychiatry (01-12-2021)“…Studying phenotypic and genetic characteristics of age at onset (AAO) and polarity at onset (PAO) in bipolar disorder can provide new insights into disease…”
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In Psychosis, Cortical Interneurons Overexpress DNA-Methyltransferase 1
Published in Proceedings of the National Academy of Sciences - PNAS (08-02-2005)“…Cortical DNA-methyltransferase 1 (DNMT1) is preferentially expressed in interneurons secreting GABA where it very likely contributes to promoter CpG island…”
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GABAergic dysfunction in schizophrenia : new treatment strategies on the horizon
Published in Psychopharmacologia (01-07-2005)“…Cortical gamma-aminobutyric acid (GABA)ergic neurons contribute to the orchestration of pyramidal neuron population firing as follows: (1) by releasing GABA on…”
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Genetics of specific clinical phenotypes of bipolar disorder: a focus on mania with psychosis
Published in European neuropsychopharmacology (01-10-2017)Get full text
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P.1.a.029 - Genetics of specific clinical phenotypes of bipolar disorder: a focus on mania with psychosis
Published in European neuropsychopharmacology (01-10-2017)Get full text
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