Search Results - "Velazquez, Eric M"
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Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella
Published in Cell host & microbe (13-04-2016)“…The mammalian intestine is host to a microbial community that prevents pathogen expansion through unknown mechanisms, while antibiotic treatment can increase…”
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Commensal Enterobacteriaceae Protect against Salmonella Colonization through Oxygen Competition
Published in Cell host & microbe (09-01-2019)“…Neonates are highly susceptible to infection with enteric pathogens, but the underlying mechanisms are not resolved. We show that neonatal chick colonization…”
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Host-mediated sugar oxidation promotes post-antibiotic pathogen expansion
Published in Nature (London) (30-06-2016)“…Antibiotic usage in humans can increase the risk of Salmonella infection by an unknown mechanism; this paper reveals that the antibiotic streptomycin increases…”
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5-Aminosalicylic Acid Ameliorates Colitis and Checks Dysbiotic Escherichia coli Expansion by Activating PPAR-γ Signaling in the Intestinal Epithelium
Published in mBio (19-01-2021)“…5-Aminosalicylic acid (5-ASA), a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, is a widely used first-line medication for the treatment of…”
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Collateral Damage: Microbiota-Derived Metabolites and Immune Function in the Antibiotic Era
Published in Cell host & microbe (13-08-2014)“…Our long-standing evolutionary association with gut-associated microbial communities has given rise to an intimate relationship, which affects many aspects of…”
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Vitamin A supplementation boosts control of antibiotic-resistant Salmonella infection in malnourished mice
Published in PLoS neglected tropical diseases (01-10-2020)“…Disseminated disease from non-typhoidal Salmonella enterica strains results in >20% mortality globally. Barriers to effective treatment include emerging…”
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Virulence factors enhance Citrobacter rodentium expansion through aerobic respiration
Published in Science (American Association for the Advancement of Science) (16-09-2016)“…Citrobacter rodentium uses a type III secretion system (T3SS) to induce colonie crypt hyperplasia in mice, thereby gaining an edge during its competition with…”
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Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes
Published in Cell host & microbe (08-06-2022)“…Changes in the microbiota composition are associated with many human diseases, but factors that govern strain abundance remain poorly defined. We show that a…”
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Endogenous Enterobacteriaceae underlie variation in susceptibility to Salmonella infection
Published in Nature microbiology (01-06-2019)“…Lack of reproducibility is a prominent problem in biomedical research. An important source of variation in animal experiments is the microbiome, but little is…”
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Inflammation-associated alterations to the intestinal microbiota reduce colonization resistance against non-typhoidal Salmonella during concurrent malaria parasite infection
Published in Scientific reports (05-10-2015)“…Childhood malaria is a risk factor for disseminated infections with non-typhoidal Salmonella (NTS) in sub-Saharan Africa. While hemolytic anemia and an altered…”
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Effect of Adopting a Timothy Hay–based Diet at Weaning or in Adulthood on Urinary Tract Parameters in Strain 13/N Guinea Pigs (Cavia porcellus)
Published in Journal of the American Association for Laboratory Animal Science (01-07-2024)“…Type of feed is an important consideration in herbivore colony management, yet limited studies report on the effects of diet on common conditions such as…”
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Iron acquisition pathways and colonization of the inflamed intestine by Salmonella enterica serovar Typhimurium
Published in International journal of medical microbiology (01-12-2016)“…Highlights • Ferric iron uptake via IroN and TonB uptake contributes to fitness of Salmonella typhimurium in the inflamed intestine. • Ferrous iron uptake via…”
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Influence of arthritis-related protein (BBF01) on infectivity of Borrelia burgdorferi B31
Published in BMC microbiology (07-05-2013)“…Lyme borreliosis, caused by tick-borne Borrelia burgdorferi, is a multi-phasic, multi-system disease in humans. Similar to humans, C3H mice develop arthritis…”
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Spore Preparation Protocol for Enrichment of Clostridia from Murine Intestine
Published in Bio-protocol (20-05-2017)“…In recent years, many spore-forming commensal Clostridia found in the gut have been discovered to promote host physiology, immune development, and protection…”
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Effect of Adopting a Timothy Hay-based Diet at Weaning or in Adulthood on Urinary Tract Parameters in Strain 13/N Guinea Pigs (Cavia porcellus)
Published in Journal of the American Association for Laboratory Animal Science (01-07-2024)“…Type of feed is an important consideration in herbivore colony management, yet limited studies report on the effects of diet on common conditions such as…”
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16
Usefulness of Right Ventricular Fractional Area Change to Predict Death, Heart Failure, and Stroke Following Myocardial Infarction (from the VALIANT ECHO Study)
Published in The American journal of cardiology (01-03-2008)“…Severe right ventricular dysfunction independent of left ventricular ejection fraction increased the risk of heart failure (HF) and death after myocardial…”
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Prediction of All-Cause Mortality and Heart Failure Admissions From Global Left Ventricular Longitudinal Strain in Patients With Acute Myocardial Infarction and Preserved Left Ventricular Ejection Fraction
Published in Journal of the American College of Cardiology (11-06-2013)“…Objectives This study sought to test the hypothesis that semiautomated calculation of left ventricular global longitudinal strain (GLS) can identify high-risk…”
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Comparison of Clinical Characteristics and Outcomes of Patients With versus Without Diabetes Mellitus and With versus Without Angina Pectoris (From the Duke Databank for Cardiovascular Disease)
Published in The American journal of cardiology (01-06-2017)“…Abstract Angina pectoris (AP) has different prognostic implications in various populations. Patients with diabetes mellitus (DM) may experience neuropathy such…”
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Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial
Published in The Lancet (British edition) (03-04-2010)“…Summary Background The Avoiding Cardiovascular Events through Combination Therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial showed that…”
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Revascularization in Severe Left Ventricular Dysfunction
Published in Journal of the American College of Cardiology (17-02-2015)“…Abstract The highest-risk patients with heart failure with reduced ejection fraction are those with ischemic cardiomyopathy and severe left ventricular…”
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