Search Results - "Velayudhan, R"

Bacillus thuringiensis israelensis (Bti) for the control of dengue vectors: systematic literature review by Boyce, R., Lenhart, A., Kroeger, A., Velayudhan, R., Roberts, B., Horstick, O.

“…Objective To systematically review the literature on the effectiveness of Bacillus thuringiensis israelensis (Bti), when used as a single agent in the field,…”
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Efficient gene editing in induced pluripotent stem cells enabled by an inducible adenine base editor with tunable expression by Nandy, Krittika, Babu, Dinesh, Rani, Sonam, Joshi, Gaurav, Ijee, Smitha, George, Anila, Palani, Dhavapriya, Premkumar, Chitra, Rajesh, Praveena, Vijayanand, S., David, Ernest, Murugesan, Mohankumar, Velayudhan, Shaji R.

“…The preferred method for disease modeling using induced pluripotent stem cells (iPSCs) is to generate isogenic cell lines by correcting or introducing…”
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Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications by Bagchi, Abhirup, Devaraju, Nivedhitha, Chambayil, Karthik, Rajendiran, Vignesh, Venkatesan, Vigneshwaran, Sayed, Nilofer, Pai, Aswin Anand, Nath, Aneesha, David, Ernest, Nakamura, Yukio, Balasubramanian, Poonkuzhali, Srivastava, Alok, Thangavel, Saravanabhavan, Mohankumar, Kumarasamypet M., Velayudhan, Shaji R.

“…Numerous genes exert multifaceted roles in hematopoiesis. Therefore, we generated novel lineage-specific RNA interference (RNAi) lentiviral vectors,…”
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Editing of homologous globin genes by nickase-deficient base editor mitigates large intergenic deletions in HSPCs by George, Anila, Sadanandan, Poornasree, Ravi, Nithin Sam, Vaishnavi, B., Marepally, Srujan, Thangavel, Saravanbhavan, Velayudhan, Shaji R., Srivastava, Alok, Mohankumar, Kumarasamypet M

“…Recent studies have shown that base editing, even with single-strand breaks, could result in large deletions of the interstitial regions while targeting…”
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Global distribution and environmental suitability for chikungunya virus, 1952 to 2015 by Nsoesie, E O, Kraemer, M U, Golding, N, Pigott, D M, Brady, O J, Moyes, C L, Johansson, M A, Gething, P W, Velayudhan, R, Khan, K, Hay, S I, Brownstein, J S

“…Chikungunya fever is an acute febrile illness caused by the chikungunya virus (CHIKV), which is transmitted to humans by Aedes mosquitoes. Although chikungunya…”
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Generation and characterization of induced pluripotent stem cell line IITGi001-A derived from adult human primary dermal fibroblasts by Raina, Khyati, Joshi, Gaurav, Modak, Kirti, Premkumar, Chitra, Priyanka, Sweety, Rajesh, Praveena, Velayudhan, Shaji R., Thummer, Rajkumar P.

“…Adult human primary dermal fibroblasts [ATCC (PCS-201-012)] were reprogrammed by transfection of oriP/EBNA-1 based episomal plasmids expressing OCT3/4, SOX2,…”
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Optimization of SARS-CoV-2 Pseudovirion Production in Lentivirus Backbone With a Novel Liposomal System by Mahalingam, Gokulnath, Rachamalla, Hari Krishnareddy, Arjunan, Porkizhi, Periyasami, Yogapriya, M, Salma, Thangavel, Saravanabhavan, Mohankumar, Kumarasamypet M, Moorthy, Mahesh, Velayudhan, Shaji R, Srivastava, Alok, Marepally, Srujan

“…Due to the fast mutating nature of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the development of novel therapeutics, vaccines, and…”
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Efficacy and community effectiveness of larvivorous fish for dengue vector control by Han, W. W., Lazaro, A., McCall, P. J., George, L., Runge‐Ranzinger, S., Toledo, J., Velayudhan, R., Horstick, O.

“…Objective To evaluate the efficacy and community effectiveness of larvivorous fish for the control of dengue vectors and dengue transmission, when used as a…”
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Modulating retinoid-X-receptor alpha (RXRA) expression sensitizes chronic myeloid leukemia cells to imatinib in vitro and reduces disease burden in vivo by Rajamani, Bharathi M, Illangeswaran, Raveen Stephen Stallon, Benjamin, Esther Sathya Bama, Balakrishnan, Balaji, Jebanesan, Daniel Zechariah Paul, Das, Saswati, Pai, Aswin Anand, Vidhyadharan, Rakhi Thalayattu, Mohan, Ajith, Karathedath, Sreeja, Abraham, Aby, Mathews, Vikram, Velayudhan, Shaji R, Balasubramanian, Poonkuzhali

“…The ligand-activated transcription factors, nuclear hormone receptors (NHRs), remain unexplored in hematological malignancies except for retinoic acid receptor…”
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Community effectiveness of copepods for dengue vector control: systematic review by Lazaro, A., Han, W. W., Manrique‐Saide, P., George, L., Velayudhan, R., Toledo, J., Runge Ranzinger, S., Horstick, O.

“…Objective Vector control remains the only available method for primary prevention of dengue. Several interventions exist for dengue vector control, with…”
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Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editors by Prasad, Kirti, Devaraju, Nivedhitha, George, Anila, Ravi, Nithin Sam, Paul, Joshua, Mahalingam, Gokulnath, Rajendiran, Vignesh, Panigrahi, Lokesh, Venkatesan, Vigneshwaran, Lakhotiya, Kartik, Periyasami, Yogapriya, Pai, Aswin Anand, Nakamura, Yukio, Kurita, Ryo, Balasubramanian, Poonkuzhali, Thangavel, Saravanabhavan, Velayudhan, Shaji R., Newby, Gregory A., Marepally, Srujan, Srivastava, Alok, Mohankumar, Kumarasamypet M.

“…β-thalassemia/HbE results from mutations in the β-globin locus that impede the production of functional adult hemoglobin. Base editors (BEs) could facilitate…”
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Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies by Venkatesan, Vigneshwaran, Christopher, Abisha Crystal, Rhiel, Manuel, Azhagiri, Manoj Kumar K., Babu, Prathibha, Walavalkar, Kaivalya, Saravanan, Bharath, Andrieux, Geoffroy, Rangaraj, Sumathi, Srinivasan, Saranya, Karuppusamy, Karthik V., Jacob, Annlin, Bagchi, Abhirup, Pai, Aswin Anand, Nakamura, Yukio, Kurita, Ryo, Balasubramanian, Poonkuzhali, Pai, Rekha, Marepally, Srujan Kumar, Mohankumar, Kumarasamypet Murugesan, Velayudhan, Shaji R., Boerries, Melanie, Notani, Dimple, Cathomen, Toni, Srivastava, Alok, Thangavel, Saravanabhavan

“…Reactivation of fetal hemoglobin (HbF) is a commonly adapted strategy to ameliorate β-hemoglobinopathies. However, the continued production of defective adult…”
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Comprehensive Analysis of microRNAs in Human Adult Erythropoiesis by Nath, Aneesha, Rayabaram, Janakiram, Ijee, Smitha, Bagchi, Abhirup, Chaudhury, Anurag Dutta, Roy, Debanjan, Chambayil, Karthik, Singh, Jyoti, Nakamura, Yukio, Velayudhan, Shaji R

“…MicroRNAs (miRNAs) are small non-coding RNAs, which play an important role in various cellular and developmental processes. The study of miRNAs in…”
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Direct Generation of Immortalized Erythroid Progenitor Cell Lines from Peripheral Blood Mononuclear Cells by Bagchi, Abhirup, Nath, Aneesha, Thamodaran, Vasanth, Ijee, Smitha, Palani, Dhavapriya, Rajendiran, Vignesh, Venkatesan, Vigneshwaran, Datari, Phaneendra, Pai, Aswin Anand, Janet, Nancy Beryl, Balasubramanian, Poonkuzhali, Nakamura, Yukio, Srivastava, Alok, Mohankumar, Kumarasamypet Murugesan, Thangavel, Saravanabhavan, Velayudhan, Shaji R

“…Reliable human erythroid progenitor cell (EPC) lines that can differentiate to the later stages of erythropoiesis are important cellular models for studying…”
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Efficient deletion of microRNAs using CRISPR/Cas9 with dual guide RNAs by Ijee, Smitha, Chambayil, Karthik, Chaudhury, Anurag Dutta, Bagchi, Abhirup, Modak, Kirti, Das, Saswati, Benjamin, Esther Sathya Bama, Rani, Sonam, Paul, Daniel Zechariah, Nath, Aneesha, Roy, Debanjan, Palani, Dhavapriya, Priyanka, Sweety, Ravichandran, Rakshini, Kumary, Betty K, Sivamani, Yazhini, S, Vijayanand, Babu, Dinesh, Nakamura, Yukio, Thamodaran, Vasanth, Balasubramanian, Poonkuzhali, Velayudhan, Shaji R

“…MicroRNAs (miRNAs) are short non-coding RNAs that play crucial roles in gene regulation, exerting post-transcriptional silencing, thereby influencing cellular…”
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Quality control guidelines for clinical-grade human induced pluripotent stem cell lines by Sullivan, Stephen, Stacey, Glyn N, Akazawa, Chihiro, Aoyama, Naoki, Baptista, Ricardo, Bedford, Patrick, Bennaceur Griscelli, Annelise, Chandra, Amit, Elwood, Ngaire, Girard, Mathilde, Kawamata, Shin, Hanatani, Tadaaki, Latsis, Theodoros, Lin, Stephen, Ludwig, Tenneille E, Malygina, Tamara, Mack, Amanda, Mountford, Joanne C, Noggle, Scott, Pereira, Lygia V, Price, Jack, Sheldon, Michael, Srivastava, Alok, Stachelscheid, Harald, Velayudhan, Shaji R, Ward, Natalie J, Turner, Marc L, Barry, Jacqueline, Song, Jihwan

“…Use of clinical-grade human induced pluripotent stem cell (iPSC) lines as a starting material for the generation of cellular therapeutics requires…”
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Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2 by George, Anila, Ravi, Nithin Sam, Prasad, Kirti, Panigrahi, Lokesh, Koikkara, Sanya, Rajendiran, Vignesh, Devaraju, Nivedhitha, Paul, Joshua, Pai, Aswin Anand, Nakamura, Yukio, Kurita, Ryo, Balasubramanian, Poonkuzhali, Thangavel, Saravanabhavan, Marepally, Srujan, Velayudhan, Shaji R, Srivastava, Alok, Mohankumar, Kumarasamypet M

“…Sickle cell anaemia (SCA) is one of the common autosomal recessive monogenic disorders, caused by a transverse point mutation (GAG > GTG) at the sixth codon of…”
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Reviewing the development, evidence base, and application of the revised dengue case classification by Horstick, O, Farrar, J, Lum, L, Martinez, E, San Martin, J L, Ehrenberg, J, Velayudhan, R, Kroeger, A

“…With the example of dengue, an evidence-based approach to prospectively develop a case classification is described, gathering evidence for identifying strength…”
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A novel deletion of β-globin promoter causing high HbA2 in an Indian population by Mayuranathan, Thiyagaraj, Rayabaram, Janakiram, Edison, Eunice Sindhuvi, Srivastava, Alok, Velayudhan, Shaji R

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Gene Editing in Human Induced Pluripotent Stem Cells Using Doxycycline-Inducible CRISPR-Cas9 System by Thamodaran, Vasanth, Rani, Sonam, Velayudhan, Shaji R

“…Induced pluripotent stem cells (iPSCs) generated from patients are a valuable tool for disease modelling, drug screening, and studying the functions of…”
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