Search Results - "Velasco, Brenda"
-
1
Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance
Published in Cell stem cell (01-08-2019)“…Hematopoietic cell transplantation can correct hematological and immunological disorders by replacing a diseased blood system with a healthy one, but this…”
Get full text
Journal Article -
2
Curative islet and hematopoietic cell transplantation in diabetic mice without toxic bone marrow conditioning
Published in Cell reports (Cambridge) (08-11-2022)“…Mixed hematopoietic chimerism can promote immune tolerance of donor-matched transplanted tissues, like pancreatic islets. However, adoption of this strategy is…”
Get full text
Journal Article -
3
Lipid nanoparticles as nano-Trojan-horses for siRNA delivery and gene-knockdown
Published in Journal of colloid and interface science (01-02-2025)“…[Display omitted] The therapeutic messenger RNA strategies, such as those using small interfering RNAs, take several advantages (versatility, efficiency and…”
Get full text
Journal Article -
4
Development of functional hybrid scaffolds for wound healing applications
Published in iScience (15-04-2022)“…Hybrid hydrogels composed of chitosan (CS) and hyaluronic acid (HA) and collagen (Coll) were prepared by polyelectrolyte complex self-assembly. These scaffolds…”
Get full text
Journal Article -
5
Comparative studies of cutins from lime (Citrus aurantifolia) and grapefruit (Citrus paradisi) after TFA hydrolysis
Published in Phytochemistry (Oxford) (01-12-2017)“…Grapefruit and lime cutins were analyzed and compared in order to obtain information about their cutin architecture. This was performed using a sequential…”
Get full text
Journal Article -
6
Combined Therapeutics for Atherosclerosis Treatment Using Polymeric Nanovectors
Published in Pharmaceutics (22-01-2022)“…Atherosclerosis is an underlying risk factor in cardiovascular diseases (CVDs). The combination of drugs with microRNAs (miRNA) inside a single nanocarrier has…”
Get full text
Journal Article -
7
5-Azacytidine depletes HSCs and synergizes with an anti-CD117 antibody to augment donor engraftment in immunocompetent mice
Published in Blood advances (12-10-2021)“…Depletion of hematopoietic stem cells (HSCs) is used therapeutically in many malignant and nonmalignant blood disorders in the setting of a hematopoietic cell…”
Get full text
Journal Article -
8
Adsorption and Interaction of Bovine Serum Albumin and Pluronic P103 Triblock Copolymer on a Gold Electrode: Double-Layer Capacitance Measurements
Published in ACS omega (21-07-2020)“…The interactions of proteins and other molecules and their adsorption onto substrates is a fascinating topic that has been applied to surface technologies,…”
Get full text
Journal Article -
9
Assessing the Effect of Surface Coating on the Stability, Degradation, Toxicity and Cell Endocytosis/Exocytosis of Upconverting Nanoparticles
Published in Journal of colloid and interface science (15-08-2024)“…[Display omitted] Lanthanide-doped up-converting nanoparticles (UCNPs) have emerged as promising biomedical tools in recent years. Most research efforts were…”
Get full text
Journal Article -
10
Antineoplastic effect of paclitaxel-loaded polymeric nanocapsules on malignant human ovarian carcinoma cells (SKOV-3)
Published in Journal of molecular liquids (15-08-2023)“…•Relatively small polymeric based-nanocapsules were obtained for paclitaxel (PTX) encapsulation.•PTX was largely encapsulated inside the nanocapsules and…”
Get full text
Journal Article -
11
Cholesterol Conjugated Elastin-like Recombinamers: Molecular Dynamics Simulations, Conformational Changes, and Bioactivity
Published in ACS applied materials & interfaces (19-11-2024)Get full text
Journal Article -
12
5-Azacytidine Depletes Hematopoietic Stem Cells and Synergizes with an Anti-CD117 Antibody to Augment Engraftment of Donor Stem Cells in Immunocompetent Mice
Published in Blood (05-11-2020)“…Monoclonal antibody (mAb)-targeting of CD117 (c-Kit) present on hematopoietic stem cells (HSC) is an emerging conditioning strategy for hematopoietic cell…”
Get full text
Journal Article -
13
Competition for engineering tenure-track faculty positions in the United States
Published in PNAS nexus (01-05-2024)“…How likely are engineering PhD graduates to get a tenure-track faculty position in the United States? To answer this question, we analyzed aggregated yearly…”
Get full text
Journal Article -
14
Pluronic F127/carfilzomib-based nanomicelles as promising nanocarriers: synthesis, characterization, biological, and in silico evaluations
Published in Journal of molecular liquids (15-01-2022)“…•F127 oil-in-water-based microemulsions for CFZ encapsulation.•Pluronic F127/CFZ nanomicelles showed a high encapsulation efficiency and sustained release…”
Get full text
Journal Article -
15
Light excitation of gold Nanorod-Based hybrid nanoplatforms for simultaneous bimodal phototherapy
Published in Journal of molecular liquids (01-05-2023)“…•AuNRs incorporating the dye ICG inside the external polymeric coating were obtained.•Polymeric LbL coating makes the AuNRs-based platform colloidally stable…”
Get full text
Journal Article -
16
Role of surface functionalization and biomolecule structure on protein corona adsorption and conformation onto anisotropic metallic nanoparticles
Published in Journal of molecular liquids (15-03-2024)“…In the biological milieu, nanoparticles (NPs) interact with different biomolecules, particularly proteins, leading to the formation of an interfacial corona,…”
Get full text
Journal Article -
17
Inhibiting HER3 Hyperphosphorylation in HER2‐Overexpressing Breast Cancer through Multimodal Therapy with Branched Gold Nanoshells
Published in Small (Weinheim an der Bergstrasse, Germany) (01-12-2023)“…Treatment failure in breast cancers overexpressing human epidermal growth factor receptor 2 (HER2) is associated mainly to the upregulation of human epidermal…”
Get full text
Journal Article -
18
Monodisperse superparamagnetic nanoparticles separation adsorbents for high-yield removal of arsenic and/or mercury metals in aqueous media
Published in Journal of molecular liquids (01-08-2021)“…Recyclable magnetic-based nanoadsorbents with large capacity of heavy metal ion extraction from aqueous environments. [Display omitted] The use of magnetic…”
Get full text
Journal Article -
19
JSP191 As a Single-Agent Conditioning Regimen Results in Successful Engraftment, Donor Myeloid Chimerism, and Production of Donor Derived Naïve Lymphocytes in Patients with Severe Combined Immunodeficiency (SCID)
Published in Blood (23-11-2021)“…Successful hematopoietic cell transplantation (HCT) relies on conditioning of recipients to deplete hematopoietic stem cells (HSC) from marrow niches to allow…”
Get full text
Journal Article -
20
Simple thermal treatment to improve the MRI and magnetic hyperthermia performance of hybrid iron Oxide-Mesoporous silica nanocarriers
Published in Journal of molecular liquids (15-03-2024)“…[Display omitted] •Magnetic SBA-15 nanocomposites with mesoporous structure, large surface area and higher load capacity.•A straightforward heat treatment to…”
Get full text
Journal Article