Search Results - "Velalopoulou, Anastasia"

A facile approach to hydrophilic oxidized fullerenes and their derivatives as cytotoxic agents and supports for nanobiocatalytic systems by Zygouri, Panagiota, Spyrou, Konstantinos, Mitsari, Efstratia, Barrio, María, Macovez, Roberto, Patila, Michaela, Stamatis, Haralambos, Verginadis, Ioannis I., Velalopoulou, Anastasia P., Evangelou, Angelos M., Sideratou, Zili, Gournis, Dimitrios, Rudolf, Petra

“…A facile, environment-friendly, versatile and reproducible approach to the successful oxidation of fullerenes (oxC 60 ) and the formation of highly hydrophilic…”
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Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605) by Pietrofesa, Ralph A, Velalopoulou, Anastasia, Albelda, Steven M, Christofidou-Solomidou, Melpo

“…The interaction of asbestos fibers with macrophages generates harmful reactive oxygen species (ROS) and subsequent oxidative cell damage that are key processes…”
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Preclinical models of radiation-induced cardiac toxicity: Potential mechanisms and biomarkers by Dreyfuss, Alexandra D, Velalopoulou, Anastasia, Avgousti, Harris, Bell, Brett I, Verginadis, Ioannis I

“…Radiation therapy (RT) is an important modality in cancer treatment with >50% of cancer patients undergoing RT for curative or palliative intent. In patients…”
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The Flaxseed-Derived Lignan Phenolic Secoisolariciresinol Diglucoside (SDG) Protects Non-Malignant Lung Cells from Radiation Damage by Velalopoulou, Anastasia, Tyagi, Sonia, Pietrofesa, Ralph A, Arguiri, Evguenia, Christofidou-Solomidou, Melpo

“…Plant phenolic compounds are common dietary antioxidants that possess antioxidant and anti-inflammatory properties. Flaxseed (FS) has been reported to be…”
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Towards Novel Multifunctional Pillared Nanostructures: Effective Intercalation of Adamantylamine in Graphene Oxide and Smectite Clays by Spyrou, Konstantinos, Potsi, Georgia, Diamanti, Evmorfia K., Ke, Xiaoxing, Serestatidou, Eleni, Verginadis, Ioannis I., Velalopoulou, Anastasia P., Evangelou, Angelos M., Deligiannakis, Yiannis, Van Tendeloo, Gustaaf, Gournis, Dimitrios, Rudolf, Petra

“…Multifunctional pillared materials are synthesized by the intercalation of cage‐shaped adamantylamine (ADMA) molecules into the interlayer space of graphite…”
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Antitumor effects of the electromagnetic resonant frequencies derived from the 1H NMR spectrum of Ph3Sn(Mercaptonicotinic)SnPh3 complex by Verginadis, Ioannis I., Karkabounas, Spyridon Ch, Simos, Yannis V., Velalopoulou, Anastasia P., Peschos, Dimitrios, Avdikos, Antonis, Zelovitis, Ioannis, Papadopoulos, Nikolaos, Dounousi, Evangelia, Ragos, Vasilios, Evangelou, Angelos M.

“…The aim of this article is to investigate the potential cytotoxic and antitumor effects of the resonant electromagnetic fields (rEMFs) derived from the 1H NMR…”
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Synthetic Secoisolariciresinol Diglucoside (LGM2605) Protects Human Lung in an Ex Vivo Model of Proton Radiation Damage by Velalopoulou, Anastasia, Chatterjee, Shampa, Pietrofesa, Ralph A, Koziol-White, Cynthia, Panettieri, Reynold A, Lin, Liyong, Tuttle, Stephen, Berman, Abigail, Koumenis, Constantinos, Christofidou-Solomidou, Melpo

“…Radiation therapy for the treatment of thoracic malignancies has improved significantly by directing of the proton beam in higher doses on the targeted tumor…”
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Effects of catechin and epicatechin on superoxide dismutase and glutathione peroxidase activity, in vivo by Simos, Yannis V, Verginadis, Ioannis I, Toliopoulos, Ioannis K, Velalopoulou, Anastasia P, Karagounis, Ilias V, Karkabounas, Spyridon C., Evangelou, Angelos M

“…Objectives The objective of this study was to investigate the effects of catechin and epicatechin on the activity of the endogenous antioxidant enzymes…”
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Novel Double-Hit Model of Radiation and Hyperoxia-Induced Oxidative Cell Damage Relevant to Space Travel by Pietrofesa, Ralph A, Velalopoulou, Anastasia, Lehman, Stacey L, Arguiri, Evguenia, Solomides, Pantelis, Koch, Cameron J, Mishra, Om P, Koumenis, Constantinos, Goodwin, Thomas J, Christofidou-Solomidou, Melpo

“…Spaceflight occasionally requires multiple extravehicular activities (EVA) that potentially subject astronauts to repeated changes in ambient oxygen…”
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Analgesic effect of the electromagnetic resonant frequencies derived from the NMR spectrum of morphine by Verginadis, Ioannis I., Simos, Yannis V., Velalopoulou, Anastasia P., Vadalouca, Athina N., Kalfakakou, Vicky P., Karkabounas, Spyridon Ch, Evangelou, Angelos M.

“…Exposure to various types of electromagnetic fields (EMFs) affects pain specificity (nociception) and pain inhibition (analgesia). Previous study of ours has…”
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Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System by Diffenderfer, Eric S., Verginadis, Ioannis I., Kim, Michele M., Shoniyozov, Khayrullo, Velalopoulou, Anastasia, Goia, Denisa, Putt, Mary, Hagan, Sarah, Avery, Stephen, Teo, Kevin, Zou, Wei, Lin, Alexander, Swisher-McClure, Samuel, Koch, Cameron, Kennedy, Ann R., Minn, Andy, Maity, Amit, Busch, Theresa M., Dong, Lei, Koumenis, Costas, Metz, James, Cengel, Keith A.

“…Recent studies suggest that ultrahigh-dose-rate, “FLASH,” electron radiation therapy (RT) decreases normal tissue damage while maintaining tumor response…”
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The role of U.S. thermal stress in modulating the vascular transport dynamics in the brain tumors by Arvanitis, Costas, Kim, Chulyong, Guo, Yutong, Velalopoulou, Anastasia

“…We hypothesized that localized thermal stress could change the cerebrovascular transport dynamics in the brain tumor micro-environment. Our findings, using a…”
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FLASH Proton Radiotherapy Spares Normal Epithelial and Mesenchymal Tissues While Preserving Sarcoma Response by Velalopoulou, Anastasia, Karagounis, Ilias V, Cramer, Gwendolyn M, Kim, Michele M, Skoufos, Giorgos, Goia, Denisa, Hagan, Sarah, Verginadis, Ioannis I, Shoniyozov, Khayrullo, Chiango, June, Cerullo, Michelle, Varner, Kelley, Yao, Lutian, Qin, Ling, Hatzigeorgiou, Artemis G, Minn, Andy J, Putt, Mary, Lanza, Matthew, Assenmacher, Charles-Antoine, Radaelli, Enrico, Huck, Jennifer, Diffenderfer, Eric, Dong, Lei, Metz, James, Koumenis, Constantinos, Cengel, Keith A, Maity, Amit, Busch, Theresa M

“…In studies of electron and proton radiotherapy, ultrahigh dose rates of FLASH radiotherapy appear to produce fewer toxicities than standard dose rates while…”
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Key biological mechanisms involved in high-LET radiation therapies with a focus on DNA damage and repair by Nikitaki, Zacharenia, Velalopoulou, Anastasia, Zanni, Vassiliki, Tremi, Ioanna, Havaki, Sophia, Kokkoris, Michael, Gorgoulis, Vassilis G, Koumenis, Constantinos, Georgakilas, Alexandros G

“…DNA damage and repair studies are at the core of the radiation biology field and represent also the fundamental principles informing radiation therapy (RT)…”
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A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression by Verginadis, Ioannis I., Avgousti, Harris, Monslow, James, Skoufos, Giorgos, Chinga, Frank, Kim, Kyle, Leli, Nektaria Maria, Karagounis, Ilias V., Bell, Brett I., Velalopoulou, Anastasia, Salinas, Carlo Salas, Wu, Victoria S., Li, Yang, Ye, Jiangbin, Scott, David A., Osterman, Andrei L., Sengupta, Arjun, Weljie, Aalim, Huang, Menggui, Zhang, Duo, Fan, Yi, Radaelli, Enrico, Tobias, John W., Rambow, Florian, Karras, Panagiotis, Marine, Jean-Christophe, Xu, Xiaowei, Hatzigeorgiou, Artemis G., Ryeom, Sandra, Diehl, J. Alan, Fuchs, Serge Y., Puré, Ellen, Koumenis, Constantinos

“…Bidirectional signalling between the tumour and stroma shapes tumour aggressiveness and metastasis. ATF4 is a major effector of the Integrated Stress Response,…”
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Ultrafast Tracking of Oxygen Dynamics During Proton FLASH by El Khatib, Mirna, Van Slyke, Alexander L., Velalopoulou, Anastasia, Kim, Michele M., Shoniyozov, Khayrullo, Allu, Srinivasa Rao, Diffenderfer, Eric S., Busch, Theresa M., Wiersma, Rodney D., Koch, Cameron J., Vinogradov, Sergei A.

“…Radiation therapy delivered at ultrafast dose rates, known as FLASH RT, has been shown to provide a therapeutic advantage compared with conventional radiation…”
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A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance by Dreyfuss, Alexandra D, Goia, Denisa, Shoniyozov, Khayrullo, Shewale, Swapnil V, Velalopoulou, Anastasia, Mazzoni, Susan, Avgousti, Harris, Metzler, Scott D, Bravo, Paco E, Feigenberg, Steven J, Ky, Bonnie, Verginadis, Ioannis I, Koumenis, Constantinos

“…Radiation-induced cardiotoxicity is a significant concern in thoracic oncology patients. However, the basis for this disease pathology is not well…”
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Closed-loop trans-skull ultrasound hyperthermia leads to improved drug delivery from thermosensitive drugs and promotes changes in vascular transport dynamics in brain tumors by Kim, Chulyong, Guo, Yutong, Velalopoulou, Anastasia, Leisen, Johannes, Motamarry, Anjan, Ramajayam, Krishna, Aryal, Muna, Haemmerich, Dieter, Arvanitis, Costas D

“…Effective drug delivery in brain tumors remains a major challenge in oncology. Although local hyperthermia and stimuli-responsive delivery systems, such as…”
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Intercellular pathways of cancer treatment-related cardiotoxicity and their therapeutic implications: the paradigm of radiotherapy by Logotheti, Stella, Pavlopoulou, Athanasia, Rudsari, Hamid Khoshfekr, Galow, Anne-Marie, Kafalı, Yağmur, Kyrodimos, Efthymios, Giotakis, Aris I., Marquardt, Stephan, Velalopoulou, Anastasia, Verginadis, Ioannis I., Koumenis, Constantinos, Stiewe, Thorsten, Zoidakis, Jerome, Balasingham, Ilangko, David, Robert, Georgakilas, Alexandros G.

“…Advances in cancer therapeutics have improved patient survival rates. However, cancer survivors may suffer from adverse events either at the time of therapy or…”
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Abstract IA-019: Preclinical studies with proton FLASH radiotherapy in mice and canines: Biological effects, biophysical considerations and potential mechanisms by Verginadis, Ioannis, Velalopoulou, Anastasia, Hagan, Sarah, Goia, Denisa, Shoniyozov, Khayrullo, Kim, Michele, Diffenderfer, Eric, Dong, Lei, Metz, James, Cengel, Keith, Busch, Theresa, Minn, Andy, Maity, Amit, Koumenis, Constantinos

“…Multiple studies indicate that ultra-high dose rate, “FLASH” Radiotherapy (F-RT), augments the therapeutic index compared to Standard RT (S-RT) by sparing…”
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