Search Results - "Vela , Driton"

Hepcidin, an emerging and important player in brain iron homeostasis by Vela, Driton

“…Hepcidin is emerging as a new important factor in brain iron homeostasis. Studies suggest that there are two sources of hepcidin in the brain; one is local and…”
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Low hepcidin in liver fibrosis and cirrhosis; a tale of progressive disorder and a case for a new biochemical marker by Vela, Driton

“…Liver fibrosis is a precursor of liver cirrhosis, which is associated with increased mortality. Though liver biopsy remains the gold standard for the diagnosis…”
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The Dual Role of Hepcidin in Brain Iron Load and Inflammation by Vela, Driton

“…Hepcidin is the major regulator of systemic iron metabolism, while the role of this peptide in the brain has just recently been elucidated. Studies suggest a…”
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Iron Metabolism in Prostate Cancer; From Basic Science to New Therapeutic Strategies by Vela, Driton

“…An increasing amount of research has recently strengthened the case for the existence of iron dysmetabolism in prostate cancer. It is characterized with a wide…”
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Keeping heart homeostasis in check through the balance of iron metabolism by Vela, Driton

“…Highly active cardiomyocytes need iron for their metabolic activity. In physiological conditions, iron turnover is a delicate process which is dependent on…”
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Balance of cardiac and systemic hepcidin and its role in heart physiology and pathology by Vela, Driton

“…Hepcidin is the main regulator of iron metabolism in tissues. Its serum levels are mostly correlated with the levels of hepcidin expression from the liver, but…”
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The Role of Insulin Therapy in Correcting Hepcidin Levels in Patients with Type 2 Diabetes Mellitus by Gjorgievska , Elizabeta S, Jakupaj , Muharrem, Leshoski , Jovica, Mladenov , Mitko, Sopi , Ramadan B, Vela , Driton, Hadzi-Petrushev , Nikola

“…Objectives: Iron overload can cause or contribute to the pathogenesis of type 2 diabetes mellitus (T2DM), but how the major parameters of iron metabolism…”
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Insulin treatment corrects hepcidin but not YKL-40 levels in persons with type 2 diabetes mellitus matched by body mass index, waist-to-height ratio, C-reactive protein and Creatinine by Vela, Driton, Leshoski, Jovica, Vela, Zana, Jakupaj, Muharrem, Mladenov, Mitko, Sopi, Ramadan B

“…It has been shown that hepcidin and YKL-40 levels change in persons with insulin resistance in different circumstances. However, variations of the levels of…”
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Systemic and local hepcidin as emerging and important peptides in renal homeostasis and pathology by Vela, Driton

“…Recent data suggest that the importance of hepcidin goes beyond its classical role in controlling systemic iron metabolism. Local hepcidins are emerging as…”
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Differential regulation of hepcidin in cancer and non-cancer tissues and its clinical implications by Vela, Driton, Vela-Gaxha, Zana

“…Hepcidin is a crucial peptide for regulating cellular iron efflux. Because iron is essential for cell survival, especially for highly active cells, such as…”
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Left ventricular markers of global dyssynchrony predict limited exercise capacity in heart failure, but not in patients with preserved ejection fraction by Bajraktari, Gani, Batalli, Arlind, Poniku, Afrim, Ahmeti, Artan, Olloni, Rozafa, Hyseni, Violeta, Vela, Zana, Morina, Besim, Tafarshiku, Rina, Vela, Driton, Rashiti, Premtim, Haliti, Edmond, Henein, Michael Y

“…The aim of this study was to prospectively examine echocardiographic parameters that correlate and predict functional capacity assessed by 6 min walk test…”
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HbA1C, finding the right target in 2018 by Vela, Driton

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Efficacy and safety of tocilizumab versus standard care/placebo in patients with COVID‐19; a systematic review and meta‐analysis of randomized clinical trials by Vela, Driton, Vela‐Gaxha, Zana, Rexhepi, Mjellma, Olloni, Rozafa, Hyseni, Violeta, Nallbani, Rajmonda

“…Aims Tocilizumab has emerged as an important therapy in treating patients with coronavirus disease (COVID‐19). Our purpose was to evaluate the efficacy and…”
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Differential regulation of hepcidin in cancer and noncancer tissues and its clinical implications by Driton Vela, Zana Vela-Gaxha

“…Hepcidin is a crucial peptide for regulating cellular iron efflux. Because iron is essential for cell survival, especially for highly active cells, such as…”
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Low Hepcidin in Type 2 Diabetes Mellitus: Examining the Molecular Links and Their Clinical Implications by Vela, Driton, Sopi, Ramadan B., Mladenov, Mitko

“…The relationship between iron and glucose metabolism has been evidenced strongly, but the molecular mediation of this connection is just being revealed. The…”
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Quercetin Reverses the Enhanced Contractile Responses of Tracheal Smooth Muscle of Neonatal Rats Exposed to Hyperoxia by Kryeziu, Islam, Thaçi, Qëndrim, Reçica, Shkëlzen, Kurshumliu, Fisnik, Vela, Driton, Mladenov, Mitko, Basholli, Mimoza, Sopi, Ramadan B

“…Abstract only Neonatal hyperoxia increases contraction and decreases the relaxation of airway smooth muscle (ASM), and the balance between these processes in…”
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EP 1 Receptor Agonists Augment Hyperoxia‐Induced Airway Hyperresponsiveness by Sopi, Ramadan B, Neziri, Burim, Mladenov, Mitko, Vela, Driton, Lajçi, Njomza, Thaqi, Qendrim, Bislimi, Kemajl, Jakupaj, Muharrem, Lajçi, Azem

“…Abstract only Neonatal hyperoxia is associated with airway hyperresponsiveness. It was shown that hyperoxia upregulates prostaglandin E 2 synthesis, which has…”
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