Is Endoscopic Retrograde Cholangiopancreatography Valuable and Safe in Children of All Ages?

ABSTRACT Objective: To evaluate indications, findings, therapies, safety, and technical success of endoscopic retrograde cholangiopancreatography (ERCP) in children of the Emma Children's Hospital Academic Medical Centre in Amsterdam, the Netherlands. Design: Descriptive. Retrospective analysis...

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Bibliographic Details
Published in:	Journal of pediatric gastroenterology and nutrition Vol. 48; no. 1; pp. 66 - 71
Main Authors:	Vegting, IL, Tabbers, MM, Taminiau, JAJM, Aronson, DC, Benninga, MA, Rauws, EAJ
Format:	Journal Article
Language:	English
Published:	Hagerstown, MD Lippincott Williams & Wilkins, Inc 01-01-2009 Lippincott Williams & Wilkins
Subjects:	Adolescent Biliary Atresia - diagnosis Biliary Atresia - surgery Biliary Tract Diseases - diagnosis Biliary Tract Diseases - surgery Biological and medical sciences Child Child, Preschool Cholangiopancreatography, Endoscopic Retrograde - adverse effects Cholangitis, Sclerosing - diagnosis Cholangitis, Sclerosing - surgery Choledochal Cyst - diagnosis Choledochal Cyst - surgery Choledocholithiasis - diagnosis Choledocholithiasis - surgery Digestive system Endoscopic retrograde cholangiopancreatography Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Gastroenterology. Liver. Pancreas. Abdomen Humans Infant Infant, Newborn Infants Investigative techniques, diagnostic techniques (general aspects) Jaundice, Obstructive - diagnosis Jaundice, Obstructive - surgery Liver - injuries Male Medical sciences Pancreas - injuries Pancreatic and hepatobiliary diseases Pancreatic Diseases - diagnosis Pancreatic Diseases - surgery Pancreatitis - diagnosis Pancreatitis - surgery Radiodiagnosis. Nmr imagery. Nmr spectrometry Retrospective Studies Safety Treatment Outcome Vertebrates: anatomy and physiology, studies on body, several organs or systems Human Cholangiopancreatography Obesity Endoscopic retrograde cholangiopancreatography Pancreatic and hepatobiliary diseases Radiodiagnosis Nutrition Nutrition disorder Metabolic diseases Infant Infants Hepatobiliary disease Gastroenterology Digestive diseases Endoscopy Child Age Nutritional status Pancreatic disease
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Summary:	ABSTRACT Objective: To evaluate indications, findings, therapies, safety, and technical success of endoscopic retrograde cholangiopancreatography (ERCP) in children of the Emma Children's Hospital Academic Medical Centre in Amsterdam, the Netherlands. Design: Descriptive. Retrospective analysis by medical records. Patients and Methods: Information was obtained by chart review of patients between 0 and 18 years who underwent ERCP from 1995 to 2005 in our center. The following data were analyzed: indications, findings, therapies, safety, and technical success. Success was defined as obtaining accurate diagnostic information or succeeding in endoscopic therapy. Results: Sixty‐one children (age 3 days to 16.9 years, mean age 7.0 years) underwent a total of 99 ERCPs. Of those patients, 51% (31/61) were younger than 1 year, 84% had biliary indications, and 16% had pancreatic indications for the performance of ERCP. The complication rate was 4% (4/99) and included substantial pancreatitis and mild irritated pancreas. No complications occurred in children younger than 1 year. Conclusions: ERCP is a safe and valuable procedure for children of all ages with suspicion of pancreaticobiliary diseases. Indications for ERCP are different for children and adults. A laparotomy could be prevented in 12% of children with suspicion of biliary atresia. Further research is required to determine the role of MRCP versus ERCP.
Bibliography:	The authors report no conflicts of interest. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0277-2116 1536-4801
DOI:	10.1097/MPG.0b013e31817a24cf