Search Results - "Vegi, Ganga Modi Naidu"

Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenic tumours by Kulhari, Hitesh, M Pharm, Pooja, Deep, M Pharm, Shrivastava, Shweta, MS Pharm, Telukutala, Srinivasa R., MS Pharm, Barui, Ayan K., MSc, Patra, Chitta Ranjan, PhD, Naidu Vegi, Ganga Modi, PhD, Adams, David J., PhD, Sistla, Ramakrishna, PhD

“…Abstract Docetaxel (DTX) is an anticancer drug that is used alone and in combination with other drugs to treat tumours. However, it suffers from the drawback…”
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Synthesis of 2,5‐Disubstituted‐1,3,4‐oxadiazole Derivatives and Their Evaluation as Anticancer and Antimycobacterial Agents by Polkam, Naveen, Kummari, Bhaskar, Rayam, Parsharamulu, Brahma, Umarani, Ganga Modi Naidu, Vegi, Balasubramanian, Sridhar, Anireddy, Jaya Shree

“…A series of regioisomeric (2,5‐dimethoxybenzoic acid, veratric acid) analogues were prepared by swapping the carboxylic motif to its oxadiazole bioisostere and…”
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Emulsifying properties of gum kondagogu (Cochlospermum gossypium), a natural biopolymer by Vegi, Ganga Modi Naidu, Sistla, Ramakrishna, Srinivasan, Palaniappan, Beedu, Sashidhar Rao, Khar, Roop K, Diwan, Prakash V

“…BACKGROUND: Natural polymers are widely used as emulsifying agents in the food and pharmaceutical industries because of their low cost, biocompatibility and…”
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Abietic acid attenuates RANKL induced osteoclastogenesis and inflammation associated osteolysis by inhibiting the NF‐KB and MAPK signaling by Thummuri, Dinesh, Guntuku, Lalita, Challa, Veerabhadra Swamy, Ramavat, Ravinder Naik, Naidu, Vegi Ganga Modi

“…Osteoporosis is a major debilitating cause of fractures and decreases the quality of life in elderly patients. Bone homeostasis is maintained by bone forming…”
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Targeting TLR4/3 using chlorogenic acid ameliorates LPS+POLY I:C-induced acute respiratory distress syndrome via alleviating oxidative stress-mediated NLRP3/NF-κB axis by Jain, Siddhi, Saha, Pritam, Syamprasad, Nayadi Parambil, Panda, Samir Rajan, Rajdev, Bishal, Jannu, Arun Kumar, Sharma, Pawan, Naidu, Vegi Ganga Modi

“…Acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) is a life-threatening condition caused due to significant pulmonary and systemic…”
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Formulation characterization of lecithin organogel as topical drug delivery system for psoriasis: In‐vitro permeation and preclinical evaluation by Bule, Prajakta, Kadkanje, Prashant, Kshirsagar, Ravikiran, Puppala, Eswara Rao, Naidu, Vegi Ganga Modi, Chella, Naveen

“…Psoriasis is a chronic inflammatory and proliferative skin disease that causes pathological skin changes and has a substantial impact on the quality of patient…”
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Carnosic acid attenuates renal injury in an experimental model of rat cisplatin-induced nephrotoxicity by Sahu, Bidya Dhar, Rentam, Kiran Kumar Reddy, Putcha, Uday Kumar, Kuncha, Madhusudana, Vegi, Ganga Modi Naidu, Sistla, Ramakrishna

“…► Nephrotoxicity is the dose limiting side effects of cisplatin, an anticancer agent. ► Carnosic acid significantly attenuated the renal injury, oxidative…”
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Synthesis, docking, in vitro and in vivo antidiabetic activity of pyrazole‐based 2,4‐thiazolidinedione derivatives as PPAR‐γ modulators by Naim, Mohd. Javed, Alam, Ozair, Alam, Md. Jahangir, Shaquiquzzaman, Mohammad, Alam, Md. Mumtaz, Naidu, Vegi Ganga Modi

“…The design, synthesis, structure–activity relationship, and biological activity of 2,4‐thiazolidinedione derivatives as peroxisome proliferator‐activated…”
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Immunonano-Lipocarrier-Mediated Liver Sinusoidal Endothelial Cell-Specific RUNX1 Inhibition Impedes Immune Cell Infiltration and Hepatic Inflammation in Murine Model of NASH by Tripathi, Dinesh Mani, Rohilla, Sumati, Kaur, Impreet, Siddiqui, Hamda, Rawal, Preety, Juneja, Pinky, Kumar, Vikash, Kumari, Anupama, Naidu, Vegi Ganga Modi, Ramakrishna, Seeram, Banerjee, Subham, Puria, Rekha, Sarin, Shiv K., Kaur, Savneet

“…Background: Runt-related transcription factor (RUNX1) regulates inflammation in non-alcoholic steatohepatitis (NASH). Methods: We performed in vivo targeted…”
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Polymeric Core–Shell Combinatorial Nanomedicine for Synergistic Anticancer Therapy by Shanavas, Asifkhan, Jain, Nishant K, Kaur, Navneet, Thummuri, Dinesh, Prasanna, Maruthi, Prasad, Rajendra, Naidu, Vegi Ganga Modi, Bahadur, Dhirendra, Srivastava, Rohit

“…Core–shell nanostructures are promising platforms for combination drug delivery. However, their complicated synthesis process, poor stability, surface…”
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Curcumin potentiates the anti-arthritic effect of prednisolone in Freund's complete adjuvant-induced arthritic rats by Kuncha, Madhusudana, Naidu, Vegi Ganga Modi, Sahu, Bidya Dhar, Gadepalli, Shankar Ganesh, Sistla, Ramakrishna

“…Objectives The present study was aimed at investigating the effect of curcumin in combination with prednisolone for the effective treatment of arthritis with…”
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Anti-inflammatory potential of thienopyridines as possible alternative to NSAIDs by Madhusudana, Kuncha, Shireesha, Boyapati, Naidu, Vegi Ganga Modi, Ramakrishna, Sistla, Narsaiah, Banda, Rao, Akkinepally Raghuram, Diwan, Prakash V.

“…The present study was designed to evaluate the anti-inflammatory and antiarthritic activity of the new synthetic thienopyridine analogs. The anti-inflammatory…”
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Multifunctional Synthetic Amphiphile for Niche Therapeutic Applications: Mitigation of MRSA Biofilms and Potential in Wound Healing by Dey, Poulomi, Puppala, Eswara Rao, Naidu, Vegi Ganga Modi, Das, Gopal, Ramesh, Aiyagari

“…The relentless menace of implant- and skin wound-associated infections caused by methicillin-resistant Staphylococcus aureus (MRSA) biofilms demands the design…”
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Synthesis of C 5 -tethered indolyl-3-glyoxylamide derivatives as tubulin polymerization inhibitors by Guggilapu, Sravanthi Devi, Lalita, Guntuku, Reddy, T Srinivasa, Prajapti, Santosh Kumar, Nagarsenkar, Atulya, Ramu, Shymala, Brahma, Uma Rani, Lakshmi, Uppa Jaya, Vegi, Ganga Modi Naidu, Bhargava, Suresh K, Babu, Bathini Nagendra

“…A series of C -tethered Indolyl-3-glyoxylamide derivatives were synthesized and evaluated for their in vitro cytotoxic activity against DU145 (prostate), PC-3…”
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Synthesis of C5-tethered indolyl-3-glyoxylamide derivatives as tubulin polymerization inhibitors by Guggilapu, Sravanthi Devi, Lalita, Guntuku, Reddy, T. Srinivasa, Prajapti, Santosh Kumar, Nagarsenkar, Atulya, Ramu, Shymala, Brahma, Uma Rani, Lakshmi, Uppa Jaya, Vegi, Ganga Modi Naidu, Bhargava, Suresh K., Babu, Bathini Nagendra

“…A series of C5-tethered Indolyl-3-glyoxylamide derivatives were synthesized and evaluated for their in vitro cytotoxic activity against DU145 (prostate), PC-3…”
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Synthesis and Biological Evaluation of Thieno[2, 3‐d]pyrimidine‐amides as Potential Anticancer Agents by Ramya, Posa Venkata Sri, Thatikonda, Sowjanya, Angapelly, Srinivas, Babu, Bathini Nagendra, Naidu, Vegi Ganga Modi, Kamal, Ahmed

“…In our search towards the development of potential anticancer agents, a new class of N‐(3‐(thieno[2, 3‐d]pyrimidin‐4‐ylamino)phenyl)amides (10 a−x) were…”
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Identification of phytoconstituents of Memecylon sisparense gamble leaf and evaluation against cisplatin-induced oxidative renal damage in mice by Uppu, Jaya, Challa, Veerabhadra, Bhattula, Devender, Naidu Vegi, Ganga, Jojula, Malathi, Syed, Asha

“…Background: Memecylon sisparense Gamble (MSG) belongs to Melastomataceae family, having a wide range of pharmacological activities such as antioxidant,…”
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