Search Results - "Veerman, Selene"
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Treatment for Negative Symptoms in Schizophrenia: A Comprehensive Review
Published in Drugs (New York, N.Y.) (01-09-2017)“…Negative symptoms (such as amotivation and diminished expression) associated with schizophrenia are a major health concern. Adequate treatment would mean…”
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Risk of clozapine-associated agranulocytosis and mandatory white blood cell monitoring: Can the regulations be relaxed?
Published in Schizophrenia research (01-06-2024)“…After the introduction of clozapine eight Finnish patients died after developing agranulocytosis. Clozapine was withdrawn from the market and only reintroduced…”
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COVID-19: Risks, Complications, and Monitoring in Patients on Clozapine
Published in Pharmacopsychiatry (01-01-2022)“…The Dutch Clozapine Collaboration Group is frequently asked for advice about the management of clozapine-treated patients when infected with or vaccinated…”
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Clozapine and COVID‐19 Vaccination: Effects on blood levels and leukocytes. An observational cohort study
Published in Acta psychiatrica Scandinavica (01-08-2022)“…Objective To investigate the safety of COVID‐19 vaccination in patients on clozapine as regards plasma clozapine concentration and haematological parameters…”
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Simvastatin Augmentation for Patients With Early-Phase Schizophrenia-Spectrum Disorders: A Double-Blind, Randomized Placebo-Controlled Trial
Published in Schizophrenia bulletin (08-07-2021)“…Abstract Schizophrenia-spectrum disorders (SSD) are associated with increased inflammatory markers, both in brain and periphery. Augmentation with drugs that…”
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To continue or not to continue? Antipsychotic medication maintenance versus dose-reduction/discontinuation in first episode psychosis: HAMLETT, a pragmatic multicenter single-blind randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (07-02-2020)“…Antipsychotic medication is effective for symptomatic treatment in schizophrenia-spectrum disorders. After symptom remission, continuation of antipsychotic…”
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Clozapine and the risk of haematological malignancies
Published in The Lancet. Psychiatry (01-07-2022)Get full text
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Memantine add-on to clozapine treatment for residual negative symptoms of schizophrenia
Published in Psychopharmacology (01-12-2017)Get full text
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Associations Between Polygenic Risk Score Loading, Psychosis Liability, and Clozapine Use Among Individuals With Schizophrenia
Published in JAMA psychiatry (Chicago, Ill.) (01-02-2023)“…Predictors consistently associated with psychosis liability and course of illness in schizophrenia (SCZ) spectrum disorders (SSD), including the need for…”
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Psychiatrists effect on positive symptom severity and daily functioning during pharmacotherapy for first-episode psychosis patients
Published in Scientific reports (02-10-2024)“…Clinical outcomes after a first-episode of psychosis (FEP) are heterogeneous. Many patient-related factors such as gender and comorbidity have been studied to…”
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Comprehensive dissection of prevalence rates, sex differences, and blood level-dependencies of clozapine-associated adverse drug reactions
Published in Psychiatry research (01-12-2023)“…•Hypersalivation and weight gain were the two most common adverse drug reactions.•Younger participants were more prone to experiencing common adverse drug…”
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Medication strategies in first episode psychosis patients: A survey among psychiatrists
Published in Early intervention in psychiatry (01-02-2022)“…Aim There is an ongoing debate regarding the optimal timing of discontinuation of antipsychotic drugs for patients with first episode psychosis. Although most…”
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Genetic Susceptibility to Clozapine-Induced Agranulocytosis/Neutropenia Across Ethnicities: Results From a New Cohort of Turkish and Other Caucasian Participants, and Meta-Analysis
Published in Schizophrenia bulletin open (01-01-2020)“…Abstract Clozapine (CLZ) is considered the most effective antipsychotic, but its use is associated with neutropenia (CIN) and agranulocytosis (CIA). Although…”
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