Search Results - "Veeramachaneni, Ratna"

Changes in abundance of oral microbiota associated with oral cancer by Schmidt, Brian L, Kuczynski, Justin, Bhattacharya, Aditi, Huey, Bing, Corby, Patricia M, Queiroz, Erica L S, Nightingale, Kira, Kerr, A Ross, DeLacure, Mark D, Veeramachaneni, Ratna, Olshen, Adam B, Albertson, Donna G

“…Individual bacteria and shifts in the composition of the microbiome have been associated with human diseases including cancer. To investigate changes in the…”
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Characterization of neutrophil function in Papillon‐Lefèvre syndrome by Roberts, Helen, White, Phillipa, Dias, Irundika, McKaig, Sarah, Veeramachaneni, Ratna, Thakker, Nalin, Grant, Melissa, Chapple, Iain

“…Neutrophils from PLS patients exhibit functional abnormalities possibly explaining pre‐pubertal periodontitis, in their disease. Papillon‐Lefévre syndrome is a…”
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Anti-cancer and analgesic effects of resolvin D2 in oral squamous cell carcinoma by Ye, Yi, Scheff, Nicole N., Bernabé, Daniel, Salvo, Elizabeth, Ono, Kentaro, Liu, Cheng, Veeramachaneni, Ratna, Viet, Chi T., Viet, Dan T., Dolan, John C., Schmidt, Brian L.

“…Oral cancer is often painful and lethal. Oral cancer progression and pain may result from shared pathways that involve unresolved inflammation and elevated…”
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Oncogenes overexpressed in metastatic oral cancers from patients with pain: potential pain mediators released in exosomes by Bhattacharya, Aditi, Janal, Malvin N., Veeramachaneni, Ratna, Dolgalev, Igor, Dubeykovskaya, Zinaida, Tu, Nguyen Huu, Kim, Hyesung, Zhang, Susanna, Wu, Angie K., Hagiwara, Mari, Kerr, A. Ross, DeLacure, Mark D., Schmidt, Brian L., Albertson, Donna G.

“…Oral cancer patients experience pain at the site of the primary cancer. Patients with metastatic oral cancers report greater pain. Lack of pain identifies…”
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Metformin generates profound alterations in systemic and tumor immunity with associated antitumor effects by Veeramachaneni, Ratna, Yu, Wangjie, Newton, Jared M, Kemnade, Jan O, Skinner, Heath D, Sikora, Andrew G, Sandulache, Vlad C

“…BackgroundMetformin is a commonly used antidiabetic medication which has demonstrated promise as an anticancer agent alone and in combination with conventional…”
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Glutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response by Ahmed, Kazi Mokim, Veeramachaneni, Ratna, Deng, Defeng, Putluri, Nagireddy, Putluri, Vasanta, Cardenas, Maria F, Wheeler, David A, Decker, William K, Frederick, Andy I, Kazi, Sawad, Sikora, Andrew G, Sandulache, Vlad C, Frederick, Mitchell J

“…BackgroundThe existence of immunologically ‘cold tumors’ frequently found across a wide spectrum of tumor types represents a significant challenge for cancer…”
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TP53 gain-of-function mutation modulates the immunosuppressive microenvironment in non-HPV-associated oral squamous cell carcinoma by Shi, Yewen, Ren, Xiaoyong, Cao, Shaolong, Chen, Xi, Yuan, Bo, Brasil da Costa, Fabio Henrique, Rodriguez Rosario, Alanis E, Corona, Arnoldo, Michikawa, Chieko, Veeramachaneni, Ratna, Osman, Abdullah A, Xie, Tongxin, Wang, Wenyi, Sikora, Andrew G, Myers, Jeffrey N, Rangel, Roberto

“…, the most mutated gene in solid cancers, has a profound impact on most hallmarks of cancer. Somatic mutations occur in high frequencies in head and neck…”
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859 Regression of an immunologically ‘cold’ oral cancer model induced by modulation of the tumor microenvironment with DOXIL, anti-CTLA-4, and radiation by Brasil Da Costa, Fabio Henrique, Bhavane, Rohan, Veeramachaneni, Ratna, Cortes, Sofia, Latka, Sarah L, Badachhape, Andrew, Menon, Renuka TR, Bhandari, Prajwal, Ghaghada, Ketankumar B, Young, Simon, Annapragada, Ananth V, Sikora, Andrew

“…BackgroundThe immune-suppressive tumor microenvironment (TME) of oral cancer often hinders the effectiveness of standard treatments, including surgery,…”
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Abstract 6448: Oral cancer pain mediators released in exosomes are oncogenes with potential to shape the microenvironment and induce neuronal sensitivity by Bhattacharya, Aditi, Dubeykoskaya, Zinaida, Nguyen, Huu Tu, Dolgalev, Igor, Veeramachaneni, Ratna, Schmidt, Brian L., Albertson, Donna G.

“…Abstract Oral cancer patients suffer severe chronic and mechanically-induced pain at the site of the cancer. Patients with metastatic (N+) cancers report…”
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Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy by Veeramachaneni, Ratna, Walker, Thomas, Revil, Timothée, Weck, Antoine De, Badescu, Dunarel, O’Sullivan, James, Higgins, Catherine, Elliott, Louise, Liloglou, Triantafillos, Risk, Janet M., Shaw, Richard, Hampson, Lynne, Hampson, Ian, Dearden, Simon, Woodwards, Robert, Prime, Stephen, Hunter, Keith, Parkinson, Eric Kenneth, Ragoussis, Jiannis, Thakker, Nalin

“…We report changes in the genomic landscape in the development of head and neck squamous cell carcinomas HNSCC from potentially premalignant lesions (PPOLS) to…”
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Abstract PO-086: Generation of HPV-negative tobacco-associated oral cancer models using p53 and Cdkn2a mutant mice by Nipper, Allison, Shi, Yewen, Rosario, Alanis E. Rodriguez, Balbin, Nicholas, Rangel, Roberto, Dong, Liping, Corona, Arnoldo, Veeramachaneni, Ratna, Lozano, Guillermina, Sikora, Andrew G., Myers, Jeffrey N., Rangel, Roberto

“…Abstract Background. Genetically engineered mouse models (GEMMs) in combination with chemical carcinogenesis are powerful tools to assess the functional role…”
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Esomeprazole enhances the effect of ionizing radiation to improve tumor control by Hebert, Kassidy A., Jaramillo, Sergio, Yu, Wangjie, Wang, Min, Veeramachaneni, Ratna, Sandulache, Vlad C., Sikora, Andrew G., Bonnen, Mark D., Annapragada, Ananth V., Corry, David, Kheradmand, Farrah, Pandita, Raj K., Ludwig, Michelle S., Pandita, Tej K., Huang, Shixia, Coarfa, Cristian, Grimm, Sandra L., Perera, Dimuthu, Miles, George, Ghebre, Yohannes T.

“…The resistance of cancer cells to radiation-based treatment is a major clinical challenge confounding standard of care in cancer. This problem is particularly…”
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How genetically heterogeneous is Kabuki syndrome?: MLL2 testing in 116 patients, review and analyses of mutation and phenotypic spectrum by BANKA, Siddharth, VEERAMACHANENI, Ratna, METCALFE, Kay, CHANDLER, Kate, MAGEE, Alex, STEWART, Fiona, MCCONNELL, Vivienne Pm, DONNELLY, Deirdre E, BERLAND, Siren, HOUGE, Gunnar, MORTON, Jenny E, OLEY, Christine, REARDON, William, REVENCU, Nicole, PARK, Soo-Mi, DAVIES, Sally J, FRY, Andrew E, ANN LYNCH, Sally, GILL, Harinder, SCHWEIGER, Susann, LAM, Wayne Wk, TOLMIE, John, MOHAMMED, Shehla N, HOWARD, Emma, HOBSON, Emma, SMITH, Audrey, BLYTH, Moira, BENNETT, Christopher, VASUDEVAN, Pradeep C, GARCIA-MINAUR, Sixto, HENDERSON, Alex, GOODSHIP, Judith, WRIGHT, Michael J, FISHER, Richard, BUNSTONE, Sancha, GIBBONS, Richard, PRICE, Susan M, DE SILVA, Deepthi C, KAREN TEMPLE, I, COLLINS, Amanda L, LACHLAN, Katherine, ELMSLIE, Frances, MCENTAGART, Meriel, CASTLE, Bruce, CLAYTON-SMITH, Jill, RAGGE, Nicola, BLACK, Graeme C, DONNAI, Dian, PARKER, Michael J, CROW, Yanick J, KERR, Bronwyn, KINGSTON, Helen

“…MLL2 mutations are detected in 55 to 80% of patients with Kabuki syndrome (KS). In 20 to 45% patients with KS, the genetic basis remains unknown, suggesting…”
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Investigation of HOXA9 promoter methylation as a biomarker to distinguish oral cancer patients at low risk of neck metastasis by Uchida, Kenichiro, Veeramachaneni, Ratna, Huey, Bing, Bhattacharya, Aditi, Schmidt, Brian L, Albertson, Donna G

“…Metastasis to the cervical (neck) lymph nodes is one of the most significant clinical factors responsible for death from oral squamous cell carcinoma (SCC)…”
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Chick Embryo Chorioallantoic Membrane as a Platform for Assessing the In Vivo Efficacy of Chimeric Antigen Receptor T-cell Therapy in Solid Tumors by Nipper, Allison J, Warren, Emilie A K, Liao, Kershena S, Liu, Hsuan-Chen, Michikawa, Chieko, Porter, Caroline E, Wells, Gabrielle A, Villanueva, Mariana, Brasil da Costa, Fabio Henrique, Veeramachaneni, Ratna, Villanueva, Hugo, Suzuki, Masataka, Sikora, Andrew G

“…The fertilized chicken egg chorioallantoic membrane (CAM), a highly vascularized membrane nourishing the developing embryo, also supports rapid growth of…”
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Abstract 5174: PEGylated liposomal doxorubicin improves oral cancer response to radio-immunotherapy by Devkota, Laxman, Bhavane, Rohan, Badachhape, Andrew, Veeramachaneni, Ratna, Menon, Renuka, Bhandari, Prajwal, Cortes, Sofia, Da Costa, Fabio Henrique Brasil, Ghaghada, Ketan, Young, Simon, Sikora, Andrew G., Annapragada, Ananth V.

“…Abstract Introduction: The immunosuppressive tumor microenvironment (TME) in oral cancer inhibits response to conventional treatment (surgery +/-…”
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Abstract 4885: Changes in abundance of oral microbiota associated with oral cancer by Albertson, Donna G., Kuczynski, Justin, Bhattacharya, Aditi, Huey, Bing, Corby, Patricia M., Queiroz, Erica L. S., Nightingale, Kira, Kerr, Alexander R., DeLacure, Mark D., Veeramachaneni, Ratna, Olshen, Adam, Schmidt, Brian L.

“…Abstract Individual bacteria and shifts in the composition of the microbiome have been associated with human diseases including cancer. To investigate changes…”
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Abstract 38: Copy number aberration detected in head and neck carcinomas using OncoSNP and influence on gene expression by de Weck, Antoine, Buffa, Francesca, Veeramachaneni, Ratna, Thakker, Nalin, Ragoussis, Jiannis

“…Abstract Introduction: It is important to understand the molecular mechanisms acting in potentially malignant epithelial lesions of the oral mucosa and…”
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High resolution genomic analses of oral cancer by Veeramachaneni, Ratna

“…High density Illumina 550K BeadChip arrays were used to identify copy number and copy neutral genomic aberrations in a panel of mortal and immortal PMOLs and…”
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DEfiNING PATHOLOGIC AND MOLECULAR CHARACTERISTICS OF TONGUE LESIONS IN THE 4NQO MOUSE CARCINOGENESIS MODEL by Bhattacharya, Dr. Aditi, Veeramachaneni, Dr. Ratna, Ylstra, Dr. Bauke, Schmidt, Dr. Brian, Albertson, Dr. Donna

“…Oral cancer patients experience function-related pain, whereas patients with oral epithelial dysplasia rarely report pain. To study pain and model its onset…”
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