Search Results - "Vedvick, Thomas S."

Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant by Coler, Rhea N, Bertholet, Sylvie, Moutaftsi, Magdalini, Guderian, Jeff A, Windish, Hillarie Plessner, Baldwin, Susan L, Laughlin, Elsa M, Duthie, Malcolm S, Fox, Christopher B, Carter, Darrick, Friede, Martin, Vedvick, Thomas S, Reed, Steven G

“…Innate immune responses to vaccine adjuvants based on lipopolysaccharide (LPS), a component of gram-negative bacterial cell walls, are driven by Toll-like…”
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A synthetic adjuvant to enhance and expand immune responses to influenza vaccines by Coler, Rhea N, Baldwin, Susan L, Shaverdian, Narek, Bertholet, Sylvie, Reed, Steven J, Raman, Vanitha S, Lu, Xiuhua, DeVos, Joshua, Hancock, Kathy, Katz, Jacqueline M, Vedvick, Thomas S, Duthie, Malcolm S, Clegg, Christopher H, Van Hoeven, Neal, Reed, Steven G

“…Safe, effective adjuvants that enhance vaccine potency, including induction of neutralizing Abs against a broad range of variant strains, is an important…”
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The Plasmodium falciparum Cell-Traversal Protein for Ookinetes and Sporozoites as a Candidate for Preerythrocytic and Transmission-Blocking Vaccines by Espinosa, Diego A, Vega-Rodriguez, Joel, Flores-Garcia, Yevel, Noe, Amy R, Muñoz, Christian, Coleman, Russell, Bruck, Torben, Haney, Keith, Stevens, Alex, Retallack, Diane, Allen, Jeff, Vedvick, Thomas S, Fox, Christopher B, Reed, Steven G, Howard, Randall F, Salman, Ahmed M, Janse, Chris J, Khan, Shahid M, Zavala, Fidel, Gutierrez, Gabriel M

“…Recent studies have shown that immune responses against the cell-traversal protein for Plasmodium ookinetes and sporozoites (CelTOS) can inhibit parasite…”
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A full-length Plasmodium falciparum recombinant circumsporozoite protein expressed by Pseudomonas fluorescens platform as a malaria vaccine candidate by Noe, Amy R, Espinosa, Diego, Li, Xiangming, Coelho-Dos-Reis, Jordana G A, Funakoshi, Ryota, Giardina, Steve, Jin, Hongfan, Retallack, Diane M, Haverstock, Ryan, Allen, Jeffrey R, Vedvick, Thomas S, Fox, Christopher B, Reed, Steven G, Ayala, Ramses, Roberts, Brian, Winram, Scott B, Sacci, John, Tsuji, Moriya, Zavala, Fidel, Gutierrez, Gabriel M

“…The circumsporozoite protein (CSP) of Plasmodium falciparum is a major surface protein, which forms a dense coat on the sporozoite's surface. Preclinical…”
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Effects on Immunogenicity by Formulations of Emulsion-Based Adjuvants for Malaria Vaccines by Fox, Christopher B, Baldwin, Susan L, Vedvick, Thomas S, Angov, Evelina, Reed, Steven G

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KSAC, the First Defined Polyprotein Vaccine Candidate for Visceral Leishmaniasis by Goto, Yasuyuki, Bhatia, Ajay, Raman, Vanitha S, Liang, Hong, Mohamath, Raodoh, Picone, Alessandro F, Vidal, Silvia E Z, Vedvick, Thomas S, Howard, Randall F, Reed, Steven G

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Evaluation of the Safety and Immunogenicity in Rhesus Monkeys of a Recombinant Malaria Vaccine for Plasmodium vivax with a Synthetic Toll-Like Receptor 4 Agonist Formulated in an Emulsion by LUMSDEN, Joanne M, PICHYANGKUL, Sathit, SATTABONGKOT, Jetsumon, BENNETT, Jason W, POLHEMUS, Mark E, OCKENHOUSE, Christian F, HOWARD, Randall F, YADAVA, Anjali, SRICHAIRATANAKUL, Utaiwan, YONGVANITCHIT, Kosol, LIMSALAKPETCH, Amporn, NURMUKHAMBETOVA, Saule, KLEIN, Jennifer, BERTHOLET, Sylvie, VEDVICK, Thomas S, REED, Steven G

“…OA  Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Protection against Intestinal Amebiasis by a Recombinant Vaccine Is Transferable by T Cells and Mediated by Gamma Interferon by Guo, Xiaoti, Barroso, Lisa, Becker, Steven M, Lyerly, David M, Vedvick, Thomas S, Reed, Steven G, Petri, William A. Jr, Houpt, Eric R

“…We have previously shown that vaccination with purified Entamoeba histolytica Gal/GalNAc lectin or recombinant subunits can protect mice from intestinal…”
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Recent advances in the expression of foreign genes in Pichia pastoris by Cregg, J.M. (Oregon Graduate Institute of Science and Technology, Beaverton, OR), Vedvick, T.S, Raschke, W.C

“…The Pichia pastoris heterologous gene expression system has been utilized to produce attractive levels of a variety of intracellular and extracellular proteins…”
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A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis by Bertholet, Sylvie, Ireton, Gregory C, Ordway, Diane J, Windish, Hillarie Plessner, Pine, Samuel O, Kahn, Maria, Phan, Tony, Orme, Ian M, Vedvick, Thomas S, Baldwin, Susan L, Coler, Rhea N, Reed, Steven G

“…Despite the widespread use of the childhood vaccine against tuberculosis (TB), Mycobacterium bovis bacillus Calmette-Guérin (BCG), the disease remains a…”
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Adjuvant formulation structure and composition are critical for the development of an effective vaccine against tuberculosis by Orr, Mark T., Fox, Christopher B., Baldwin, Susan L., Sivananthan, Sandra J., Lucas, Elyse, Lin, Susan, Phan, Tony, Moon, James J., Vedvick, Thomas S., Reed, Steven G., Coler, Rhea N.

“…One third of the world is infected with Mycobacterium tuberculosis (Mtb) with eight million new cases of active tuberculosis (TB) each year. Development of a…”
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Conformational stability and disassembly of Norwalk virus-like particles. Effect of pH and temperature by Ausar, Salvador F, Foubert, Thomas R, Hudson, Mary H, Vedvick, Thomas S, Middaugh, C Russell

“…Greater than 99% of the Norwalk virus (NV) capsid consists of 180 copies of a single 58-kDa protein. Recombinantly expressed monomers self-assemble into…”
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Identification of Human T Cell Antigens for the Development of Vaccines against Mycobacterium tuberculosis by Bertholet, Sylvie, Ireton, Gregory C, Kahn, Maria, Guderian, Jeffrey, Mohamath, Raodoh, Stride, Nicole, Laughlin, Elsa M, Baldwin, Susan L, Vedvick, Thomas S, Coler, Rhea N, Reed, Steven G

“…Development of a subunit vaccine for Mycobacterium tuberculosis (Mtb) depends on the identification of Ags that induce appropriate T cell responses. Using…”
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Immunomodulatory and physical effects of oil composition in vaccine adjuvant emulsions by Fox, Christopher B, Baldwin, Susan L, Duthie, Malcolm S, Reed, Steven G, Vedvick, Thomas S

“…Highlights ► We evaluate stability and biological activity of various vaccine adjuvant emulsions employing different oils. ► Stability is similar at lower…”
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Optimized subunit vaccine protects against experimental leishmaniasis by Bertholet, Sylvie, Goto, Yasuyuki, Carter, Lauren, Bhatia, Ajay, Howard, Randall F, Carter, Darrick, Coler, Rhea N, Vedvick, Thomas S, Reed, Steven G

“…Abstract Development of a protective subunit vaccine against Leishmania spp. depends on antigens and adjuvants that induce appropriate immune responses. We…”
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In vitro evaluation of TLR4 agonist activity: Formulation effects by Misquith, Ayesha, Fung, H.W. Millie, Dowling, Quinton M., Guderian, Jeffrey A., Vedvick, Thomas S., Fox, Christopher B.

“…•TLR4 ligands are promising vaccine adjuvant candidates.•In vitro assays (e.g. macrophage cytokine production) evaluate adjuvant activity.•Different…”
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Development of a thermostable nanoemulsion adjuvanted vaccine against tuberculosis using a design-of-experiments approach by Kramer, Ryan M, Archer, Michelle C, Orr, Mark T, Dubois Cauwelaert, Natasha, Beebe, Elyse A, Huang, Po-Wei D, Dowling, Quinton M, Schwartz, Alicia M, Fedor, Dawn M, Vedvick, Thomas S, Fox, Christopher B

“…Adjuvants have the potential to increase the efficacy of protein-based vaccines but need to be maintained within specific temperature and storage conditions…”
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Elimination of the cold-chain dependence of a nanoemulsion adjuvanted vaccine against tuberculosis by lyophilization by Orr, Mark T., Kramer, Ryan M., Barnes, Lucien, Dowling, Quinton M., Desbien, Anthony L., Beebe, Elyse A., Laurance, John D., Fox, Christopher B., Reed, Steven G., Coler, Rhea N., Vedvick, Thomas S.

“…Next-generation rationally-designed vaccine adjuvants represent a significant breakthrough to enable development of vaccines against challenging diseases…”
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Intradermal immunization improves protective efficacy of a novel TB vaccine candidate by Baldwin, Susan L, Bertholet, Sylvie, Kahn, Maria, Zharkikh, Irina, Ireton, Gregory C, Vedvick, Thomas S, Reed, Steven G, Coler, Rhea N

“…Abstract We have developed the Mycobacterium tuberculosis (Mtb) fusion protein (ID83), which contains the three Mtb proteins Rv1813, Rv3620 and Rv2608. We…”
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Physicochemical characterization and biological activity of synthetic TLR4 agonist formulations by Anderson, Ryan C., Fox, Christopher B., Dutill, Timothy S., Shaverdian, Narek, Evers, Tara L., Poshusta, Garrett R., Chesko, James, Coler, Rhea N., Friede, Martin, Reed, Steven G., Vedvick, Thomas S.

“…Immunostimulatory molecules such as monophosphoryl lipid A (MPL), a Toll-like receptor 4 (TLR4) agonist, can be formulated to enhance vaccine adjuvant effects…”
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