Search Results - "Vedi, Satish"
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Future Path Toward TB Vaccine Development: Boosting BCG or Re-educating by a New Subunit Vaccine
Published in Frontiers in immunology (16-10-2018)“…Tuberculosis (TB), an infectious disease caused by ( ), kills 5,000 people per day globally. Rapid development and spread of various multi drug-resistant…”
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Heterologous Immunity between Adenoviruses and Hepatitis C Virus: A New Paradigm in HCV Immunity and Vaccines
Published in PloS one (11-01-2016)“…Adenoviruses (Ad) are commonly used as vectors for gene therapy and/or vaccine delivery. Recombinant Ad vectors are being tested as vaccines for many…”
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3
Unsolved Puzzles Surrounding HCV Immunity: Heterologous Immunity Adds Another Dimension
Published in International journal of molecular sciences (27-07-2017)“…Chronic infection with hepatitis C virus (HCV) afflicts 3% of the world's population and can lead to serious and late-stage liver diseases. Developing a…”
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Harnessing Innate Immunity to Treat Mycobacterium tuberculosis Infections: Heat-Killed Caulobacter crescentus as a Novel Biotherapeutic
Published in Cells (Basel, Switzerland) (09-02-2023)“…Tuberculosis, caused by ( ), is a serious and devastating infectious disease worldwide. Approximately a quarter of the world population harbors latent…”
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5
Immunization with Recombinant Adenoviral Vectors Expressing HCV Core or F Proteins Leads to T Cells with Reduced Effector Molecules Granzyme B and IFN-γ: A Potential New Strategy for Immune Evasion in HCV Infection
Published in Viral immunology (01-07-2015)“…Multispecific, broad, and potent T cell responses have been correlated with viral clearance in hepatitis C virus (HCV) infection. However, the majority of…”
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Heterologous Immunity between Adenoviruses and Hepatitis C Virus (HCV): Recombinant Adenovirus Vaccine Vectors Containing Antigens from Unrelated Pathogens Induce Cross-Reactive Immunity Against HCV Antigens
Published in Cells (Basel, Switzerland) (26-05-2019)“…Host immune responses play an important role in the outcome of infection with hepatitis C virus (HCV). They can lead to viral clearance and a positive outcome,…”
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Bacterially expressed recombinant envelope protein domain III of Japanese encephalitis virus (rJEV-DIII) elicits Th1 type of immune response in BALB/c mice
Published in Vaccine (16-11-2009)“…Abstract Japanese encephalitis is a major cause of encephalitis in Asia. Cases occur largely in rural areas of the South and East Asian region resulting in…”
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Novel lipopeptides of ESAT-6 induce strong protective immunity against Mycobacterium tuberculosis : Routes of immunization and TLR agonists critically impact vaccine’s efficacy
Published in Vaccine (04-11-2016)“…Highlights • Novel subunit vaccine for Mtb by using simple lipid (palmitic acid) modified peptides from ESAT-6 protein. • Lipopeptides induce significant…”
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Vaccination with 73 kDa recombinant heavy chain myosin generates high level of protection against Brugia malayi challenge in jird and mastomys models
Published in Vaccine (05-11-2008)“…Abstract We have earlier reported identification, expression and purification of a 2.0 kb cDNA clone coding for Brugia malayi heavy chain myosin which…”
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Harnessing Innate Immunity to Treat IMycobacterium tuberculosis/I Infections: Heat-Killed ICaulobacter crescentus/I as a Novel Biotherapeutic
Published in Cells (Basel, Switzerland) (01-02-2023)“…Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is a serious and devastating infectious disease worldwide. Approximately a quarter of the world…”
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11
4'-Substituted pyrimidine nucleosides lacking 5'-hydroxyl function as potential anti-HCV agents
Published in Bioorganic & medicinal chemistry letters (01-03-2014)“…Hepatitis C virus (HCV) infection is one of the major health problems worldwide. If left untreated, it leads to liver cirrhosis, liver cancer and death…”
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Recombinant adenoviral vector expressing HCV NS4 induces protective immune responses in a mouse model of Vaccinia-HCV virus infection: A dose and route conundrum
Published in Vaccine (13-05-2014)“…Highlights • Recombinant adenoviral vector containing HCV NS4 antigen can induce both cellular and humoral immune responses. • The dose and route of…”
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Heterologous Immunity and Hepatitis C Virus: Impact on Natural Infection, Pathogenesis and Vaccine Design
Published in Proceedings (01-06-2020)“…Chronic infection with the hepatitis C virus (HCV) afflicts 1%–3% of the world’s population and can lead to serious and late-stage liver diseases. Developing a…”
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Improvement in the antifilarial efficacy of doxycycline and rifampicin by combination therapy and drug delivery approach
Published in Journal of drug targeting (01-06-2010)“…The present investigation deals with the evaluation of antifilarial efficacy of liposome entrapped antiwolbachial antibiotics doxycycline and rifampicin (5…”
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A new class of pyrimidine nucleosides: inhibitors of hepatitis B and C viruses
Published in Bioorganic & medicinal chemistry letters (15-10-2012)“…Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are major health threats worldwide leading to liver cirrhosis, liver cancer and mortality…”
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Vaccination with 73kDa recombinant heavy chain myosin generates high level of protection againstBrugia malayichallenge in jird and mastomys models
Published in Vaccine (05-11-2008)“…We have earlier reported identification, expression and purification of a 2.0kb cDNA clone coding forBrugia malayiheavy chain myosin which exhibited strong…”
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17
Vaccination with 73kDa recombinant heavy chain myosin generates high level of protection against Brugia malayi challenge in jird and mastomys models
Published in Vaccine (05-11-2008)“…We have earlier reported identification, expression and purification of a 2.0kb cDNA clone coding for Brugia malayi heavy chain myosin which exhibited strong…”
Get full text
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18
Heterologous Immunity between Adenoviruses and Hepatitis C Virus: A New Paradigm in HCV Immunity and Vaccines: e0146404
Published in PloS one (01-01-2016)“…Adenoviruses (Ad) are commonly used as vectors for gene therapy and/or vaccine delivery. Recombinant Ad vectors are being tested as vaccines for many…”
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Adjuvanticity and protective immunity of Plasmodium yoelii nigeriensis blood-stage soluble antigens encapsulated in fusogenic liposome
Published in Vaccine (14-01-2009)“…Abstract In our previous studies we established fusogenic properties of lipids isolated from edible yeast Saccharomyces cerevisiae ( S. cerevisiae ). We…”
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Tetracycline treatment targeting Wolbachia affects expression of an array of proteins in Brugia malayi parasite
Published in Proteomics (Weinheim) (01-09-2009)“…Wolbachia is an intracellular endosymbiont of Brugia malayi parasite whose presence is essential for the survival of the parasite. Treatment of B…”
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