Search Results - "Vedder, Lindsey C"

Cues, context, and long-term memory: the role of the retrosplenial cortex in spatial cognition by Miller, Adam M P, Vedder, Lindsey C, Law, L Matthew, Smith, David M

“…Spatial navigation requires memory representations of landmarks and other navigation cues. The retrosplenial cortex (RSC) is anatomically positioned between…”
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Estradiol and the relationship between dendritic spines, NR2B containing NMDA receptors, and the magnitude of long-term potentiation at hippocampal CA3–CA1 synapses by Smith, Caroline C, Vedder, Lindsey C, McMahon, Lori L

“…Summary When circulating estrogen levels decline as a natural consequence of menopause and aging in women, there is an increased incidence of deficits in…”
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Estradiol-induced increase in novel object recognition requires hippocampal NR2B-containing NMDA receptors by Vedder, Lindsey C., Smith, Caroline C., Flannigan, Alaina E., McMahon, Lori L.

“…17β‐estradiol (E2), at high circulating levels, enhances learning and memory in many women, making it a clinical treatment for hormone‐related cognitive…”
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Duration of estrogen deprivation, not chronological age, prevents estrogen’s ability to enhance hippocampal synaptic physiology by Smith, Caroline C., Vedder, Lindsey C., Nelson, Amy R., Bredemann, Teruko M., McMahon, Lori L., McEwen, Bruce S.

“…Whether estrogen replacement is beneficial to cognitive health is controversial. Some studies have shown that estrogen replacement therapy (ERT) relieves…”
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Chronic intermittent ethanol exposure leads to alterations in brain-derived neurotrophic factor within the frontal cortex and impaired behavioral flexibility in both adolescent and adult rats by Fernandez, Gina M, Lew, Brandon J, Vedder, Lindsey C, Savage, Lisa M

“…Highlights • Chronic intermittent exposure to ethanol transiently alter prefrontal cortical Brain Derived Neurotrophic Factor levels. • Adults exposed to…”
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Retrosplenial Cortical Neurons Encode Navigational Cues, Trajectories and Reward Locations During Goal Directed Navigation by Vedder, Lindsey C, Miller, Adam M P, Harrison, Marc B, Smith, David M

“…The retrosplenial cortex (RSC) plays an important role in memory and spatial navigation. It shares functional similarities with the hippocampus, including the…”
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A Pivotal Role for Thiamine Deficiency in the Expression of Neuroinflammation Markers in Models of Alcohol‐Related Brain Damage by Toledo Nunes, Polliana, Vedder, Lindsey C., Deak, Terrence, Savage, Lisa M.

“…Background Alcohol‐related brain damage (ARBD) is associated with neurotoxic effects of heavy alcohol use and nutritional deficiency, in particular thiamine…”
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Interactions Between Chronic Ethanol Consumption and Thiamine Deficiency on Neural Plasticity, Spatial Memory, and Cognitive Flexibility by Vedder, Lindsey C., Hall, Joseph M., Jabrouin, Kimberly R., Savage, Lisa M.

“…Background Many alcoholics display moderate to severe cognitive dysfunction accompanied by brain pathology. A factor confounded with prolonged heavy alcohol…”
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The Retrosplenial Cortical Role in Encoding Behaviorally Significant Cues by Smith, David M, Miller, Adam M. P, Vedder, Lindsey C

“…The retrosplenial cortex (RSC) has recently begun to gain widespread interest because of its anatomical connectivity with other well-known memory structures,…”
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BDNF Regains Function in Hippocampal Long-Term Potentiation Deficits Caused by Diencephalic Damage by Vedder, Lindsey C, Savage, Lisa M

“…Thiamine deficiency (TD), commonly associated with chronic alcoholism, leads to diencephalic damage, hippocampal dysfunction, and spatial learning and memory…”
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Estradiol replacement extends the window of opportunity for hippocampal function by Vedder, Lindsey C, Bredemann, Teruko M, McMahon, Lori L

“…Abstract We previously reported that treating aged female rats, ovariectomized (OVX) as young adults, with acute proestrous levels of 17β estradiol (E2)…”
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Estradiol-induced increase in novel object recognition requires hippocampal NR2B-containing NMDAR receptors by Vedder, Lindsey C., Smith, Caroline C., Flannigan, Alaina E., McMahon, Lori L.

“…17β-estradiol (E2), at high circulating levels, enhances learning and memory in many women, making it a clinical treatment for hormone-related cognitive…”
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Effects of estrogen on hippocampal function in young adult and aged female rats by Vedder, Lindsey C

“…In rodents, the ovarian estrogen 17β-estradiol (E2) is a potent modulator of hippocampal function and the hippocampus is critical for many types of learning…”
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