Search Results - "Vedantham, Vasanth"

New Approaches to Biological Pacemakers: Links to Sinoatrial Node Development by Vedantham, Vasanth

“…Irreversible degeneration of the cardiac conduction system is a common disease that can cause activity intolerance, fainting, and death. While electronic…”
Get full text

RNA Sequencing of Mouse Sinoatrial Node Reveals an Upstream Regulatory Role for Islet-1 in Cardiac Pacemaker Cells by Vedantham, Vasanth, Galang, Giselle, Evangelista, Melissa, Deo, Rahul C, Srivastava, Deepak

“…RATIONALE:Treatment of sinus node disease with regenerative or cell-based therapies will require a detailed understanding of gene regulatory networks in…”
Get full text

Transcriptional and Epigenetic Landscape of Cardiac Pacemaker Cells: Insights Into Cellular Specialization in the Sinoatrial Node by Mandla, Ravi, Jung, Catherine, Vedantham, Vasanth

“…Cardiac pacemaker cells differentiate and functionally specialize early in embryonic development through activation of critical gene regulatory networks. In…”
Get full text

Effect of acute and chronic ethanol on atrial fibrillation vulnerability in rats by Zhang, Hao, Ruan, Hongmei, Rahmutula, Dolkun, Wilson, Emily, Marcus, Gregory M., Vedantham, Vasanth, Olgin, Jeffrey E.

“…Even though ethanol consumption has been associated with risk of atrial fibrillation (AF), little is known about how ethanol affects atrial electrophysiology…”
Get full text

Dysregulation of Cardiogenesis, Cardiac Conduction, and Cell Cycle in Mice Lacking miRNA-1-2 by Zhao, Yong, Ransom, Joshua F., Li, Ankang, Vedantham, Vasanth, von Drehle, Morgan, Muth, Alecia N., Tsuchihashi, Takatoshi, McManus, Michael T., Schwartz, Robert J., Srivastava, Deepak

“…MicroRNAs (miRNAs) are genomically encoded small RNAs used by organisms to regulate the expression of proteins generated from messenger RNA transcripts. The in…”
Get full text

Trends in Hospitalizations for Cardiac Sarcoidosis in the United States, 2005–2011 by Guo, Xiaofan, Vittinghoff, Eric, Vedantham, Vasanth, Pletcher, Mark J., Lee, Byron K.

“…Background:Cardiac sarcoidosis (CS) is a life-threatening disease that is frequently under-diagnosed.Methods and Results:We used a nationwide inpatient sample…”
Get full text

Long-Term Corticosteroid-Sparing Immunosuppression for Cardiac Sarcoidosis by Rosenthal, David G, Parwani, Purvi, Murray, Tyler O, Petek, Bradley J, Benn, Bryan S, De Marco, Teresa, Gerstenfeld, Edward P, Janmohamed, Munir, Klein, Liviu, Lee, Byron K, Moss, Joshua D, Scheinman, Melvin M, Hsia, Henry H, Selby, Van, Koth, Laura L, Pampaloni, Miguel H, Zikherman, Julie, Vedantham, Vasanth

“…Background Long-term corticosteroid therapy is the standard of care for treatment of cardiac sarcoidosis (CS). The efficacy of long-term corticosteroid-sparing…”
Get full text

Spatiotemporal regulation of an Hcn4 enhancer defines a role for Mef2c and HDACs in cardiac electrical patterning by Vedantham, Vasanth, Evangelista, Melissa, Huang, Yu, Srivastava, Deepak

“…Regional differences in cardiomyocyte automaticity permit the sinoatrial node (SAN) to function as the leading cardiac pacemaker and the atrioventricular (AV)…”
Get full text

Cholecystokinin-A signaling regulates automaticity of pacemaker cardiomyocytes by Ruan, Hongmei, Mandla, Ravi, Ravi, Namita, Galang, Giselle, Soe, Amanda W, Olgin, Jeffrey E, Lang, Di, Vedantham, Vasanth

“…The behavior of pacemaker cardiomyocytes (PCs) in the sinoatrial node (SAN) is modulated by neurohormonal and paracrine factors, many of which signal through…”
Get full text

Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System by Samal, Eva, Evangelista, Melissa, Galang, Giselle, Srivastava, Deepak, Zhao, Yong, Vedantham, Vasanth

“…Mammalian cardiac Purkinje fibers (PFs) are specified from ventricular trabecular myocardium during mid-gestation and undergo limited proliferation before…”
Get full text

The many faces of early repolarization syndrome: A single-center case series by Voskoboinik, Aleksandr, Hsia, Henry, Moss, Joshua, Vedantham, Vasanth, Tanel, Ronn E., Patel, Akash, Wojciak, Julianne, Downs, Natalie, Scheinman, Melvin M.

“…Early repolarization syndrome (ERS) is a rare but increasingly recognized cause of malignant ventricular arrhythmias. The purpose of this study was to…”
Get full text

Coupling Interval Dispersion and Body Mass Index Are Independent Predictors of Idiopathic Premature Ventricular Complex-Induced Cardiomyopathy by KAWAMURA, MITSUHARU, BADHWAR, NITISH, VEDANTHAM, VASANTH, TSENG, ZIAN H., LEE, BYRON K., LEE, RANDALL J., MARCUS, GREGORY M., OLGIN, JEFFREY E., GERSTENFELD, EDWARD P., SCHEINMAN, MELVIN M.

“…Predictors of LV Dysfunction with Idiopathic PVC Introduction Patients with frequent premature ventricular complexes (PVCs) might be at risk for the developing…”
Get full text

Heart Failure, Atrioventricular Block, and Ventricular Tachycardia in Sarcoidosis by Rosenthal, David G, Fang, Christina D, Groh, Christopher A, Nah, Gregory, Vittinghoff, Eric, Dewland, Thomas A, Vedantham, Vasanth, Marcus, Gregory M

“…Background Sarcoidosis is a granulomatous disease usually affecting the lungs, although cardiac morbidity may be common. The risk of these outcomes and the…”
Get full text

Alcohol and Vagal Tone as Triggers for Paroxysmal Atrial Fibrillation by Mandyam, Mala C., BS, Vedantham, Vasanth, MD, PhD, Scheinman, Melvin M., MD, Tseng, Zian H., MD, MAS, Badhwar, Nitish, MBBS, Lee, Byron K., MD, MAS, Lee, Randall J., MD, PhD, Gerstenfeld, Edward P., MD, Olgin, Jeffrey E., MD, Marcus, Gregory M., MD, MAS

“…Alcohol and vagal activity may be important triggers for paroxysmal atrial fibrillation (PAF), but it remains unknown if these associations occur more often…”
Get full text

Arrhythmia Monitoring and Outcomes in Patients With Cardiac Sarcoidosis: Insights From the Cardiac Sarcoidosis Consortium by Bressi, Edoardo, Crawford, Thomas C., Bogun, Frank M., Gu, Xiaokui, Ellenbogen, Kenneth A., Chicos, Alexandra B., Roukoz, Henri, Zimetbaum, Peter J., Kalbfleisch, Steven J., Murgatroyd, Francis D., Steckman, David A., Rosenfeld, Lynda E., Garlitski, Ann C., Soejima, Kyoko, Bhan, Adarsh K., Vedantham, Vasanth, Dickfeld, Timm M., De Lurgio, David B., Platonov, Pyotr G., Zipse, Matthew M., Nishiuchi, Suguru, Ortman, Matthew L., Narasimhan, Calambur, Patton, Kris K., Rosenthal, David G., Mukerji, Siddharth S., Hoogendoorn, Jarieke C., Zeppenfeld, Katja, Sauer, William H., Kron, Jordana, Bressi, Edoardo, Crawford, Thomas C., Bogun, Frank, Gu, Xiaokui, Ellenbogen, Kenneth, Chicos, Alexandra, Roukoz, Henri, Zimetbaum, Peter, Kalbfleisch, Steven, Murgatroyd, Francis, Steckman, David, Rosenfeld, Lynda, Garlitski, Ann, Soejima, Kyoko, Bhan, Adarsh, Vedantham, Vasanth, Dickfeld, Timm‐Michael, De Lurgio, David, Platonov, Pyotr, Zipse, Matthew, Nishiuchi, Suguru, Ortman, Matthew, Narasimhan, Calambur, Patton, Kris, Rosenthal, David, Mukerji, Siddharth, Hoogendoorn, Jarieke, Zeppenfeld, Katja, Sauer, William, Kron, Jordana

Get full text

Variable Clinical Features and Ablation of Manifest Nodofascicular/Ventricular Pathways by Hoffmayer, Kurt S, Lee, Byron K, Vedantham, Vasanth, Bhimani, Ashish A, Cakulev, Ivan T, Mackall, Judith A, Sahadevan, Jayakumar, Rho, Robert W, Scheinman, Melvin M

“…BACKGROUND—Manifest nodofascicular/ventricular (NFV) pathways are rare. METHODS AND RESULTS—From 2008 to 2013, 4 cases were identified with manifest NFV…”
Get full text

Clinical and electrocardiographic characteristics of idiopathic ventricular arrhythmias with right bundle branch block and superior axis: Comparison of apical crux area and posterior septal left ventricle by Kawamura, Mitsuharu, MD, Hsu, Jonathan C., MD, MAS, Vedantham, Vasanth, MD, PhD, Marcus, Gregory M., MD, MAS, Hsia, Henry H., MD, Gerstenfeld, Edward P., MD, Scheinman, Melvin M., MD, Badhwar, Nitish, MD

“…Background Right bundle branch block (RBBB) with superior axis electrocardiographic (ECG) morphology is common in patients with idiopathic ventricular…”
Get full text

Randomized trial of conventional transseptal needle versus radiofrequency energy needle puncture for left atrial access (the TRAVERSE-LA study) by Hsu, Jonathan C, Badhwar, Nitish, Gerstenfeld, Edward P, Lee, Randall J, Mandyam, Mala C, Dewland, Thomas A, Imburgia, Kourtney E, Hoffmayer, Kurt S, Vedantham, Vasanth, Lee, Byron K, Tseng, Zian H, Scheinman, Melvin M, Olgin, Jeffrey E, Marcus, Gregory M

“…Transseptal puncture is a critical step in achieving left atrial (LA) access for a variety of cardiac procedures. Although the mechanical Brockenbrough needle…”
Get full text

Ivabradine by Scheinman, Melvin M., MD, Vedantham, Vasanth, MD, PhD

“…According to a contemporary but hotly debated model (8), cellular rhythmicity in the SAN results from mutual entrainment of a membrane clock, driven by…”
Get full text

Incessant long RP tachycardia: What is the mechanism? by Kawamura, Mitsuharu, MD, Vedantham, Vasanth, MD, PhD, Dewland, Thomas A., MD, Scheinman, Melvin M., MD

Get full text