Search Results - "Vecchio, G."

A nontoxic pain killer designed by modeling of pathological receptor conformations by Spahn, V., Del Vecchio, G., Labuz, D., Rodriguez-Gaztelumendi, A., Massaly, N., Temp, J., Durmaz, V., Sabri, P., Reidelbach, M., Machelska, H., Weber, M., Stein, C.

“…Indiscriminate activation of opioid receptors provides pain relief but also severe central and intestinal side effects. We hypothesized that exploiting…”
Get full text

Metabolic syndrome in the era of COVID-19 outbreak: impact of lockdown on cardiometabolic health by Auriemma, R. S., Pirchio, R., Liccardi, A., Scairati, R., Del Vecchio, G., Pivonello, R., Colao, A.

“…Purpose COVID-19 pandemics and cardiometabolic health are mutually interconnected. Chronic metabolic diseases are known risk factors for increased mortality…”
Get full text

Survival and Complications in Thalassemia by BORGNA-PIGNATTI, C., CAPPELLINI, M. D., DE STEFANO, P., DEL VECCHIO, G. C., FORNI, G. L., GAMBERINI, M. R., GHILARDI, R., ORIGA, R., PIGA, A., ROMEO, M. A., ZHAO, H., CNAAN, A.

“…: The life expectancy of patients with thalassemia major has significantly increased in recent years, as reported by several groups in different countries…”
Get full text

Short-Term Memory Deficit Associates with miR-153-3p Upregulation in the Hippocampus of Middle-Aged Mice by Stabile, Francesca, Torromino, G., Rajendran, S., Del Vecchio, G., Presutti, C., Mannironi, C., De Leonibus, E., Mele, A., Rinaldi, A.

“…The early stages of ageing are a critical time window in which the ability to detect and identify precocious molecular and cognitive markers can make the…”
Get full text

In vivo assessment of CdSe-ZnS quantum dots: coating dependent bioaccumulation and genotoxicity by Galeone, A, Vecchio, G, Malvindi, M A, Brunetti, V, Cingolani, R, Pompa, P P

“…Semiconductor nanocrystals, or Quantum Dots (QDs), have gained considerable attention due to their unique size-dependent optical and electronic properties that…”
Get more information

Transcriptomic response in thermally challenged seahorses Hippocampus erectus: The effect of magnitude and rate of temperature change by Del Vecchio, G., Galindo-Sánchez, C.E., Tripp-Valdez, M.A., López-Landavery, E.A., Rosas, C., Mascaró, M.

“…Hippocampus erectus inhabiting the shallow coastal waters of the southern Gulf of Mexico are naturally exposed to marked temperature variations occurring in…”
Get full text

Interleukin 21 contributes to the mucosal T helper cell type 1 response in coeliac disease by Fina, D, Sarra, M, Caruso, R, Del Vecchio Blanco, G, Pallone, F, MacDonald, T T, Monteleone, G

“…In coeliac disease (CD), the upper bowel lesion is associated with a marked infiltration of the mucosa with Th1 cells secreting interferon gamma (IFNgamma) and…”
Get more information

MicroRNA-335-5p modulates spatial memory and hippocampal synaptic plasticity by Capitano, F, Camon, J, Licursi, V, Ferretti, V, Maggi, L, Scianni, M, Del Vecchio, G, Rinaldi, A, Mannironi, C, Limatola, C, Presutti, C, Mele, A

“…MicroRNAs are endogenous, noncoding RNAs crucial for the post-transcriptional regulation of gene expression. In this study, we investigated the role of…”
Get full text

Epigenetically silenced miR-34b c as a novel faecal-based screening marker for colorectal cancer by Kalimutho, M, Di Cecilia, S, Del Vecchio Blanco, G, Roviello, F, Sileri, P, Cretella, M, Formosa, A, Corso, G, Marrelli, D, Pallone, F, Federici, G, Bernardini, S

“…Background: MicroRNAs are tiny non-coding small endogenous RNAs that regulate gene expression by translational repression, mRNA cleavage and mRNA inhibition…”
Get full text

Sodium Caprate Transiently Opens Claudin-5-Containing Barriers at Tight Junctions of Epithelial and Endothelial Cells by Del Vecchio, G, Tscheik, C, Tenz, K, Helms, H. C, Winkler, L, Blasig, R, Blasig, I. E

“…Claudin-5 is a tight junction (TJ) protein which limits the diffusion of small hydrophilic molecules. Thus, it represents a potential pharmacological target to…”
Get full text

Practical approach to diagnosis of bland-looking spindle cell lesions of the breast by Magro, G, Salvatorelli, L, Puzzo, L, Piombino, E, Bartoloni, G, Broggi, G, Vecchio, G M

“…The diagnosis of bland-looking spindle cell lesions of the breast is often challenging because there is a close morphological and immunohistochemical overlap…”
Get full text

Retraction for Fusco et al., "One- and Two-Step Transformations of Rat Thyroid Epithelial Cells by Retroviral Oncogenes" by Fusco, A, Berlingieri, M. T, Di Fiore, P. P, Portella, G, Grieco, M, Vecchio, G

Get full text

Physical assessment of toxicology at nanoscale: nano dose-metrics and toxicity factor by Pompa, P P, Vecchio, G, Galeone, A, Brunetti, V, Maiorano, G, Sabella, S, Cingolani, R

“…In this work, we propose a systematic and reproducible evaluation of nanoparticles (NPs) toxicology in living systems, based on a physical assessment and…”
Get more information

IL-15 positively regulates IL-21 production in celiac disease mucosa by Sarra, M, Cupi, M L, Monteleone, I, Franzè, E, Ronchetti, G, Di Sabatino, A, Gentileschi, P, Franceschilli, L, Sileri, P, Sica, G, Del Vecchio Blanco, G, Cretella, M, Paoluzi, O A, Corazza, G R, Pallone, F, Monteleone, G

“…Celiac disease (CD)-associated inflammation is characterized by high interleukin- 21 (IL-21), but the mechanisms that control IL-21 production are not fully…”
Get full text

Dermatofibrosarcoma protuberans: a tumor in the wide spectrum of the bland-looking spindle cell lesions of the breast by Vecchio, G M, Broggi, G, Mulè, A, Piombino, E, Magro, G

“…Dermatofibrosarcoma protuberans (DFSP) is a soft tissue tumor, usually occurring as a cutaneous lesion localized to the trunk or extremities; although it has a…”
Get full text

Influence of COVID-19 Pandemic on Colorectal Cancer Presentation, Management and Outcome during the COVID-19 Pandemic by Pirozzi, B M, Siragusa, L, Baldini, G, Pellicciaro, M, Grande, M, Efrati, C, Finizio, R, Formica, V, Del Vecchio Blanco, G, Sica, G S

“…The aim of the study was to investigate whether the COVID-19 pandemic and related measures had an influence on colorectal cancer (CRC) presentation,…”
Get full text

single prenatal exposure to the endocrine disruptor 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin alters developmental myelination and remyelination potential in the rat brain by Fernández, M, Paradisi, M, D'Intino, G, Del Vecchio, G, Sivilia, S, Giardino, L, Calzà, L

“…J. Neurochem. (2010) 115, 897-909. ABSTRACT: Polychlorinated dibenzo‐dioxins, furans and dioxin‐like polychlorinated biphenyls are ubiquitous in foodstuffs of…”
Get full text

Human colonization and volcanic activity in the eastern Campania Plain (Italy) between the Eneolithic and Late Roman periods by Di Vito, M.A., Castaldo, N., de Vita, S., Bishop, J., Vecchio, G.

“…Archaeological and volcanological studies conducted in the Naples area have revealed that numerous high-intensity explosive eruptions that occurred in the past…”
Get full text

Triiodothyronine Administration Ameliorates the Demyelination/Remyelination Ratio in a Non-Human Primate Model of Multiple Sclerosis by Correcting Tissue Hypothyroidism by D'Intino, G., Lorenzini, L., Fernandez, M., Taglioni, A., Perretta, G., Del Vecchio, G., Villoslada, P., Giardino, L., Calzà, L.

“…Remyelination failure is a key landmark in chronic progression of multiple sclerosis (MS), the most diffuse demyelinating disease in human, but the reasons for…”
Get full text

Ambulatory Surgery for Perianal Crohn’s Disease: Study of Feasibility by Biancone, L., Sica, G., Del Vecchio Blanco, G., Scaramuzzo, R., Fiorani, C., Divizia, A., Di Carlo, S., Campanelli, M., Di Giorgio, A., Sibio, Simone, Arcudi, C.

“…Background. One-third of Crohn’s disease (CD) patients present perianal fistula. The gold standard in the diagnosis and treatment of symptomatic perianal…”
Get full text