Search Results - "Vecchia, Luigi"
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Improving Nonspecific Binding and Solubility: Bicycloalkyl Groups and Cubanes as para‐Phenyl Bioisosteres
Published in ChemMedChem (20-04-2017)“…Bicycloalkyl groups have been previously described as phenyl group bioisosteres. This article describes the synthesis of new building blocks allowing their…”
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Laboratory assessment of sudden sensorineural hearing loss: A case‐control study
Published in The Laryngoscope (01-10-2017)“…Objectives/Hypothesis Sudden sensorineural hearing loss (SSHL) is an otologic emergency that affects five to 30 subjects per 100,000/year. The cause of SSHL…”
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Clinical Comparison With Short-Term Follow-Up of Bioresorbable Vascular Scaffold Versus Everolimus-Eluting Stent in Primary Percutaneous Coronary Interventions
Published in The American journal of cardiology (01-09-2015)“…Objective of this study was to assess the clinical performance of bioresorbable vascular scaffold (BVS) compared to everolimus-eluting stent (EES) in subjects…”
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Cyclosporine A in Reperfused Myocardial Infarction
Published in Journal of the American College of Cardiology (02-02-2016)“…Abstract Background Whether cyclosporine A (CsA) has beneficial effects in reperfused myocardial infarction (MI) is debated. Objectives This study investigated…”
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Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: A Potent, Orally Bioavailable Human CB1/CB2 Dual Agonist with Antihyperalgesic Properties and Restricted Central Nervous System Penetration
Published in Journal of medicinal chemistry (09-08-2007)“…Selective activation of peripheral cannabinoid CB1 receptors has the potential to become a valuable therapy for chronic pain conditions as long as central…”
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Comparison by Meta-Analysis of Eptifibatide and Tirofiban to Abciximab in Patients With ST-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention
Published in The American journal of cardiology (15-07-2010)“…Adjunctive therapy with abciximab during primary percutaneous coronary intervention (PPCI) in patients with ST-elevation myocardial infarction (STEMI)…”
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Periprocedural management and in-hospital outcome of patients with indication for oral anticoagulation undergoing coronary artery stenting
Published in Journal of interventional cardiology (01-08-2009)“…In patients on oral anticoagulation (OAC) undergoing coronary stenting (PCI-S), procedural management and in-hospital outcome have never been specifically and…”
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Intraoperative coronary angiography: With or without ischemia?
Published in The Journal of thoracic and cardiovascular surgery (01-06-2009)Get full text
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A Clinical and Angiographic Study of the XIENCE V Everolimus-Eluting Coronary Stent System in the Treatment of Patients With Multivessel Coronary Artery Disease
Published in JACC. Cardiovascular interventions (01-10-2013)“…Objectives This study sought to investigate the efficacy and performance of the XIENCE V everolimus-eluting stent (EES) (Abbott Vascular, Santa Clara,…”
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Detectable serum troponin I in patients with heart failure of nonmyocardial ischemic origin
Published in The American journal of cardiology (01-07-1997)“…In conclusion detectable cTn-I in HF identifies a subgroup of patients with a particularly severe clinical and functional status, at risk for subsequent…”
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Optimized Synthesis of l-m-Tyrosine Suitable for Chemical Scale-Up
Published in Organic process research & development (01-11-2007)“…This paper demonstrates how l-m-tyrosine 1 can be synthesized on larger-scale via enzyme-catalyzed kinetic resolution of N-acyl m-tyrosine methyl ester 4…”
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Cyclosporine A in Reperfused Myocardial Infarction: The Multicenter, Controlled, Open-Label CYCLE Trial
Published in Journal of the American College of Cardiology (02-02-2016)“…Whether cyclosporine A (CsA) has beneficial effects in reperfused myocardial infarction (MI) is debated. This study investigated whether CsA improved…”
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Right ventricular function predicts transplant-free survival in idiopathic dilated cardiomyopathy
Published in Journal of cardiovascular medicine (Hagerstown, Md.) (01-09-2006)“…BACKGROUNDRight ventricular function may be reduced in patients with idiopathic dilated cardiomyopathy (IDC). The prognostic implications of right ventricular…”
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A New Practical Route for the Manufacture of (4aR,10aR)-9-Methoxy-1-methyl-6-trimethylsilanyl- 1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinoline
Published in Organic process research & development (01-11-2003)“…Different synthetic routes to the enantiomerically pure octahydrobenzo[g]quinoline derivative JNZ092 were evaluated for their suitability to rapidly prepare a…”
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Dual neurokinin NK1/NK2 antagonists : N-[(R, R)-(E)-1-arylmethyl-3-(2-oxo-azepan-3-yl)carbamoyl]allyl-N-methyl-3,5-bis( trifluoromethyl)benzamides and 3-[N'-3,5-bis(trifluoromethyl)benzoyl-N-arylmethyl-N'-methylhydrazino]-N-[(R)-2- oxo-azepan-3-yl]propionamides
Published in Bioorganic & medicinal chemistry letters (03-12-2001)Get full text
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Nitration Chemistry in Continuous Flow using Fuming Nitric Acid in a Commercially Available Flow Reactor
Published in Organic process research & development (18-11-2011)“…The paper will describe the use of flow chemistry for scaling up exothermic or hazardous nitration reactions. Such reactions often cause time delays to the…”
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Preparation of perfluoroalkane-tagged chiral auxiliaries and their application to stereoselective synthesis of a β2-amino acid building block
Published in ARKIVOC (21-09-2008)Get full text
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New information flows for cancer registries: testing the use of laboratory data in the province of Reggio Emilia, Italy
Published in European journal of cancer prevention (01-11-2020)“…Haematological malignancies often escape the standard information flows of cancer registries because diagnosis is not always based on bone marrow histology…”
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Torsade de Pointes Ventricular Tachycardia During Low Dose Intermittent Dobutamine Treatment in a Patient with Dilated Cardiomyopathy and Congestive Heart Failure
Published in Pacing and clinical electrophysiology (01-02-1999)“…The authors describe the case of a 56‐year‐old woman with chronic, severe heart failure secondary to dilated cardiomyopathy and absence of significant…”
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