Search Results - "Veatch, Olivia"

Pleiotropic genetic effects influencing sleep and neurological disorders by Veatch, Olivia J, Dr, Keenan, Brendan T, MS, Gehrman, Philip R, PhD, Malow, Beth A, Prof, Pack, Allan I, Prof

“…Summary Research evidence increasingly points to the large impact of sleep disturbances on public health. Many aspects of sleep are heritable and genes…”
Get full text

Shorter sleep duration is associated with social impairment and comorbidities in ASD by Veatch, Olivia J., Sutcliffe, James S., Warren, Zachary E., Keenan, Brendan T., Potter, Melissa H., Malow, Beth A.

“…Sleep disturbance, particularly insomnia, is common in children with autism spectrum disorders (ASD). Furthermore, disturbed sleep affects core symptoms and…”
Get full text

PHIP gene variants with protein modeling, interactions, and clinical phenotypes by Dietrich, Jordan, Lovell, Scott, Veatch, Olivia J., Butler, Merlin G.

“…Variants in the pleckstrin homology domain‐interacting protein (PHIP) gene are implicated in the clinical phenotype of Chung–Jansen syndrome, which includes…”
Get full text

Etiologic heterogeneity, pleiotropy, and polygenicity in behaviorally defined intellectual and developmental disabilities by Girault, Jessica B, Veatch, Olivia J, Won, Hyejung

Get full text

Potential Pathophysiological Pathways in the Complex Relationships between OSA and Cancer by Sánchez-de-la-Torre, Manuel, Cubillos, Carolina, Veatch, Olivia J, Garcia-Rio, Francisco, Gozal, David, Martinez-Garcia, Miguel Angel

“…Several epidemiological and clinical studies have suggested a relationship between obstructive sleep apnea (OSA) and a higher incidence or severity of cancer…”
Get full text

Next‐generation sequencing and analysis of consecutive patients referred for connective tissue disorders by Steinle, Jacob, Hossain, Waheeda A., Veatch, Olivia J., Strom, Samuel P., Butler, Merlin G.

“…Heritable connective tissue disorders (HCTDs) consist of a wide array of genetic disorders such as Ehlers–Danlos syndrome, Marfan syndrome, and osteogenesis…”
Get full text

Screening effects of HCN channel blockers on sleep/wake behavior in zebrafish by Doldur-Balli, Fusun, Smieszek, Sandra P, Keenan, Brendan T, Zimmerman, Amber J, Veatch, Olivia J, Polymeropoulos, Christos M, Birznieks, Gunther, Polymeropoulos, Mihael H

“…Hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channels generate electrical rhythmicity in various tissues although primarily heart, retina and…”
Get full text

Genetic Variation in Melatonin Pathway Enzymes in Children with Autism Spectrum Disorder and Comorbid Sleep Onset Delay by Veatch, Olivia J., Pendergast, Julie S., Allen, Melissa J., Leu, Roberta M., Johnson, Carl Hirschie, Elsea, Sarah H., Malow, Beth A.

“…Sleep disruption is common in individuals with autism spectrum disorder (ASD). Genes whose products regulate endogenous melatonin modify sleep patterns and…”
Get full text

Genomic, Clinical, and Behavioral Characterization of 15q11.2 BP1-BP2 Deletion (Burnside-Butler) Syndrome in Five Families by Baldwin, Isaac, Shafer, Robin L, Hossain, Waheeda A, Gunewardena, Sumedha, Veatch, Olivia J, Mosconi, Matthew W, Butler, Merlin G

“…The 15q11.2 BP1-BP2 deletion (Burnside-Butler) syndrome is emerging as the most common cytogenetic finding in patients with neurodevelopmental or autism…”
Get full text

ADAMTSL2 gene variant in patients with features of autosomal dominant connective tissue disorders by Steinle, Jacob, Hossain, Waheeda A., Lovell, Scott, Veatch, Olivia J., Butler, Merlin G.

“…Ehlers‐Danlos syndrome (EDS) consists of a heterogeneous group of genetically inherited connective tissue disorders. A family with three affected members over…”
Get full text

Identifying clusters of patient comorbidities associated with obstructive sleep apnea using electronic health records by Te, Tue T, Keenan, Brendan T, Veatch, Olivia J, Boland, Mary Regina, Hubbard, Rebecca A, Pack, Allan I

“…The objectives of this study were to understand the relative comorbidity burden of obstructive sleep apnea (OSA), determine whether these relationships were…”
Get full text

Connective Tissue Disorders and Fragile X Molecular Status in Females: A Case Series and Review by Butler, Merlin G, Hossain, Waheeda A, Steinle, Jacob, Gao, Harry, Cox, Eleina, Niu, Yuxin, Quach, May, Veatch, Olivia J

“…Fragile X syndrome (FXS) is the most common inherited cause of intellectual disabilities and the second most common cause after Down syndrome. FXS is an…”
Get full text

Synaptic dysfunction connects autism spectrum disorder and sleep disturbances: A perspective from studies in model organisms by Doldur-Balli, Fusun, Imamura, Toshihiro, Veatch, Olivia J., Gong, Naihua N., Lim, Diane C., Hart, Michael P., Abel, Ted, Kayser, Matthew S., Brodkin, Edward S., Pack, Allan I.

“…Sleep disturbances (SD) accompany many neurodevelopmental disorders, suggesting SD is a transdiagnostic process that can account for behavioral deficits and…”
Get full text

Clinical genetics evaluation and testing of connective tissue disorders: a cross-sectional study by Veatch, Olivia J, Steinle, Jacob, Hossain, Waheeda A, Butler, Merlin G

“…Abstract Background Heritable connective tissue disorders (HCTDs) consist of heterogeneous syndromes. The diagnosis of HCTDs is aided by genomic…”
Get full text

The dihydropyrimidine dehydrogenase gene contributes to heritable differences in sleep in mice by Keenan, Brendan T., Galante, Raymond J., Lian, Jie, Zhang, Lin, Guo, Xiaofeng, Veatch, Olivia J., Chesler, Elissa J., O’Brien, W. Timothy, Svenson, Karen L., Churchill, Gary A., Pack, Allan I.

“…Many aspects of sleep are heritable, but only a few sleep-regulating genes have been reported. Here, we leverage mouse models to identify and confirm a…”
Get full text

The Relationship Between Genetic Risk for Insomnia and Psychiatric Disorders by Chakravorty, Subhajit, Veatch, Olivia J., Mazzotti, Diego R., Gehrman, Philip R.

“…Purpose of Review Insomnia has a bi-directional relationship with both psychiatric and addictive disorders, and recent twin studies have shown an overlap in…”
Get full text

An Automated Functional Annotation Pipeline That Rapidly Prioritizes Clinically Relevant Genes for Autism Spectrum Disorder by Veatch, Olivia J, Butler, Merlin G, Elsea, Sarah H, Malow, Beth A, Sutcliffe, James S, Moore, Jason H

“…Human genetic studies have implicated more than a hundred genes in Autism Spectrum Disorder (ASD). Understanding how variation in implicated genes influence…”
Get full text

A practical approach to identifying autistic adults within the electronic health record by Malow, Beth A., Veatch, Olivia J., Niu, Xinnan, Fitzpatrick, Kasey A., Hucks, Donald, Maxwell‐Horn, Angie, Davis, Lea K.

“…The electronic health record (EHR) provides valuable data for understanding physical and mental health conditions in autism. We developed an approach to…”
Get full text

Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults by Wells, Quinn S, Veatch, Olivia J, Fessel, Joshua P, Joon, Aron Y, Levinson, Rebecca T, Mosley, Jonathan D, Held, Elizabeth P, Lindsay, Chase S, Shaffer, Christian M, Weeke, Peter E, Glazer, Andrew M, Bersell, Kevin R, Van Driest, Sara L, Karnes, Jason H, Blair, Marcia A, Lagrone, Lore W, Su, Yan R, Bowton, Erica A, Feng, Ziding, Ky, Bonnie, Lenihan, Daniel J, Fisch, Michael J, Denny, Joshua C, Roden, Dan M

“…Anthracyclines are important chemotherapeutic agents, but their use is limited by cardiotoxicity. Candidate gene and genome-wide studies have identified…”
Get full text

Evaluating Sleep Disturbances in Children With Rare Genetic Neurodevelopmental Syndromes by Veatch, Olivia J., Malow, Beth A., Lee, Hye-Seung, Knight, Aryn, Barrish, Judy O., Neul, Jeffrey L., Lane, Jane B., Skinner, Steven A., Kaufmann, Walter E., Miller, Jennifer L., Driscoll, Daniel J., Bird, Lynne M., Butler, Merlin G., Dykens, Elisabeth M., Gold, June-Anne, Kimonis, Virginia, Bacino, Carlos A., Tan, Wen-Hann, Kothare, Sanjeev V., Peters, Sarika U., Percy, Alan K., Glaze, Daniel G.

“…Adequate sleep is important for proper neurodevelopment and positive health outcomes. Sleep disturbances are more prevalent in children with genetically…”
Get full text