Search Results - "Veasey, SC"

Tumor necrosis factor alpha in sleep regulation by Rockstrom, Matthew D., Chen, Liangyu, Taishi, Ping, Nguyen, Joseph T., Gibbons, Cody M., Veasey, Sigrid C., Krueger, James M.

“…This review details tumor necrosis factor alpha (TNF) biology and its role in sleep, and describes how TNF medications influence sleep/wake activity…”
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Response of serotonergic caudal raphe neurons in relation to specific motor activities in freely moving cats by Veasey, SC, Fornal, CA, Metzler, CW, Jacobs, BL

“…Serotonergic neuronal responses during three specific motor activities were studied in nuclei raphe obscurus (NRO) and raphe pallidus (NRP) of freely moving…”
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NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea by Zhan, Guanxia, Serrano, Faridis, Fenik, Polina, Hsu, Ray, Kong, Linghao, Pratico, Domenico, Klann, Eric, Veasey, Sigrid C

“…Persons with obstructive sleep apnea may have significant residual hypersomnolence, despite therapy. Long-term hypoxia/reoxygenation events in adult mice,…”
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Long-term intermittent hypoxia in mice: protracted hypersomnolence with oxidative injury to sleep-wake brain regions by VEASEY, Sigrid C, DAVIS, Christine W, FENIK, Polina, GUANXIA ZHAN, HSU, Yeou-Jey, PRATICO, Domenico, GOW, Andrew

“…This study was designed to test the hypothesis that long-term intermittent hypoxia (LTIH), modeling the hypoxia-reoxygenation events of sleep apnea, results in…”
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Pharmacological Characterization of Serotonergic Receptor Activity in the Hypoglossal Nucleus by Fenik, Polina, Veasey, Sigrid C

“…State-dependent reductions in serotonin delivery to upper airway dilator motoneuron activity may contribute to sleep apnea. The functional significance of…”
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Long-Term Intermittent Hypoxia: Reduced Excitatory Hypoglossal Nerve Output by Veasey, Sigrid C, Zhan, Guanxia, Fenik, Polina, Pratico, Domenico

“…Humans with long-standing sleep apnea show mixed responses to serotonergic therapies for obstructive sleep apnea. We hypothesize that long-term intermittent…”
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Obstructive sleep apnea: re-evaluating our index of severity by Veasey, Sigrid Carlen

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Impaired Rapid Eye Movement Sleep in the Tg2576 APP Murine Model of Alzheimer's Disease with Injury to Pedunculopontine Cholinergic Neurons by Zhang, Bin, Veasey, Sigrid C., Wood, Marcelo A., Leng, Lewis Z., Kaminski, Christine, Leight, Susan, Abel, Ted, Lee, Virginia M.-Y., Trojanowski, John Q.

“…Impaired rapid eye movement sleep (REMS) is commonly observed in Alzheimer's disease, suggesting injury to mesopontine cholinergic neurons. We sought to…”
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Will we ever have an effective pharmacotherapy for obstructive sleep apnea? by Veasey, Sigrid Carlen

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Molecular and physiologic basis of obstructive sleep apnea by Veasey, Sigrid Carlen

“…Obstructive sleep apnea-hypopnea syndrome occurs because of various combinations of anatomic, mechanical, and neurologic anomalies that jeopardize ventilation…”
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Murine Multiple Sleep Latency Test: phenotyping sleep propensity in mice by Veasey, Sigrid C, Yeou-Jey, Hsu, Thayer, Peter, Fenik, Polina

“…Objectives were to (1) establish a measure of sleep propensity for a more comprehensive characterization of sleepiness in murine genetics and interventional…”
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Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse by Bu an, Maja, Kapfhamer, David, Valladares, Otto, Sun, Yi, Nolan, Patrick M, Rux, John J, Arnold, Steven E, Veasey, Sigrid C

“…Rab3a is the most abundant Rab (ras-associated binding) protein in the brain and has a regulatory role in synaptic vesicle trafficking. Mice with a targeted…”
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An automated system for recording and analysis of sleep in mice by VEASEY, Sigrid C, VALLADARES, Otto, FENIK, Polina, KAPFHAMER, David, SANFORD, Larry, BENINGTON, Joel, BUCAN, Maja

“…Significant differences in many aspects of sleep/wake activity among inbred strains of mice suggest genetic influences on the control of sleep. A number of…”
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Single cell laser dissection with molecular beacon polymerase chain reaction identifies 2A as the predominant serotonin receptor subtype in hypoglossal motoneurons by Zhan, G, Shaheen, F, Mackiewicz, M, Fenik, P, Veasey, S.C

“…We hypothesize that sleep state-dependent withdrawal of serotonin (5-hydroxytryptamine, 5-HT) at upper airway (UAW) dilator motoneurons contributes…”
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The effects of ondansetron on sleep-disordered breathing in the English bulldog by VEASEY, Sigrid C, CHACHKES, Jennifer, FENIK, Polina, HENDRICKS, Joan C

“…Serotonin and serotoninergic drugs have significant effects on respiration, at many sites throughout the nervous system, and serotonin has been implicated in…”
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The effects of trazodone with L-tryptophan on sleep-disordered breathing in the English bulldog by VEASEY, S. C, FENIK, P, PANCKERI, K, PACK, A. I, HENDRICKS, J. C

“…Obstructive sleep apnea hypopnea syndrome (OSAHS) is a prevalent disorder, for which there are no universally effective pharmacotherapeutics. We hypothesized…”
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The effects of serotonin antagonists in an animal model of sleep-disordered breathing by Veasey, S C, Panckeri, K A, Hoffman, E A, Pack, A I, Hendricks, J C

“…Recent studies have shown excitatory effects of serotonin on upper airway motoneurons. This excitatory effect is normally present and arises from cells in the…”
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Single-unit responses of serotonergic dorsal raphe neurons to specific motor challenges in freely moving cats by Veasey, S.C, Fornal, C.A, Metzler, C.W, Jacobs, B.L

“…Serotonin has been hypothesized to play an important role in the central control of motor function. Consistent with this hypothesis, virtually all serotonergic…”
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Hypoglossal nerve response to 5-HT3 drugs injected into the XII nucleus and vena cava in the rat by FENIK, Polina, OGAWA, Hiromasa, VEASEY, Sigrid C

“…Systemically administered ondansetron, a 5-HT3 receptor antagonist, reduces obstructive sleep-disordered breathing (OSDB) events in the English bulldog. The…”
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Serotonin : Culprit or promising therapy for obstructive sleep apnea? by VEASEY, Sigrid Carlen

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