Search Results - "Vazquez Nunez, Roberto"
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Transient DNA Occupancy of the SMC Interarm Space in Prokaryotic Condensin
Published in Molecular cell (25-07-2019)“…Multi-subunit SMC ATPases control chromosome superstructure and DNA topology, presumably by DNA translocation and loop extrusion. Chromosomal DNA is entrapped…”
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2
Docking and Molecular Dynamics Predictions of Pesticide Binding to the Calyx of Bovine β-Lactoglobulin
Published in International journal of molecular sciences (14-03-2020)“…Pesticides are used extensively in agriculture, and their residues in food must be monitored to prevent toxicity. The most abundant protein in cow's milk,…”
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Tuned SMC Arms Drive Chromosomal Loading of Prokaryotic Condensin
Published in Molecular cell (02-03-2017)“…SMC proteins support vital cellular processes in all domains of life by organizing chromosomal DNA. They are composed of ATPase “head” and “hinge“ dimerization…”
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4
Bottom‐up reconstitution of focal adhesion complexes
Published in The FEBS journal (01-06-2022)“…Focal adhesions (FA) are large macromolecular assemblies relevant for various cellular and pathological events such as migration, polarization, and metastatic…”
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Structural advances in transcription elongation
Published in Current opinion in structural biology (01-08-2022)“…Transcription is the first step of gene expression and involves RNA polymerases. After transcription initiation, RNA polymerase enters elongation followed by…”
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Gradual opening of Smc arms in prokaryotic condensin
Published in Cell reports (Cambridge) (27-04-2021)“…Multi-subunit SMC ATPases control chromosome superstructure apparently by catalyzing a DNA-loop-extrusion reaction. SMC proteins harbor an ABC-type ATPase…”
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Structural insights into integrin α5β1 opening by fibronectin ligand
Published in Science advances (01-05-2021)“…Integrin α 5 β 1 structures in resting and active states with ligand fibronectin reveal key interactions for integrin opening. Integrin α 5 β 1 is a major…”
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The tertiary origin of the allosteric activation of E. coli glucosamine-6-phosphate deaminase studied by sol-gel nanoencapsulation of its T conformer
Published in PloS one (02-05-2014)“…The role of tertiary conformational changes associated to ligand binding was explored using the allosteric enzyme glucosamine-6-phosphate (GlcN6P) deaminase…”
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Structural insights into integrin α 5 β 1 opening by fibronectin ligand
Published in Science advances (07-05-2021)“…Integrin α β is a major fibronectin receptor critical for cell migration. Upon complex formation, fibronectin and α β undergo conformational changes. While…”
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