Search Results - "Vazquez, Naiara"
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1
Synthesis of mesoporous silica nanoparticles by sol–gel as nanocontainer for future drug delivery applications
Published in Boletín de la Sociedad Española de Cerámica y Vidrio (1983) (01-05-2017)“…Development of mesoporous silica nanoparticles as carriers for drug delivery systems has increased exponentially during the last decade. The present work is…”
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Journal Article -
2
Synthesis of novel pyrazole derivatives incorporating one dicarba-closo-dodecaborane unit
Published in Tetrahedron letters (29-08-2012)“…Analogs of the CB1 receptor ligand Rimonabant incorporating one carborane cage in substitution of the piperidinyl group have been synthesized by condensation…”
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Journal Article -
3
Synthesis of D2 receptor ligand analogs incorporating one dicarba-closo-dodecaborane unit
Published in Tetrahedron letters (02-02-2011)“…Analogs of D2 receptor antagonists incorporating one carborane cage (1,2- or 1,7-dicarba-closo-dodecaborane) have been synthesized. The stability of the new…”
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Journal Article -
4
A new linker for solid-phase synthesis of heparan sulfate precursors by sequential assembly of monosaccharide building blocks
Published in Chemical communications (Cambridge, England) (01-01-2011)“…A novel ester type linker which upon cleavage releases the glycans as carbamate protected aminoglycosides was successfully employed in the sequential assembly…”
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Journal Article -
5
Strain rate jump tests on an austenitic stainless steel with a modified tensile Hopkinson split bar
Published in EPJ Web of Conferences (01-01-2018)“…This paper presents an improved experimental setup for high strain rate testing based on the modified Tensile Hopkinson Split Bar device developed previously…”
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Journal Article Conference Proceeding -
6
Synthesis and in vivo evaluation of 11C-labeled (1,7-dicarba-closo-dodecaboran-1-yl)-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}amide
Published in Journal of labelled compounds & radiopharmaceuticals (01-04-2014)“…Boron clusters, and especially dicarba‐closo‐dodecaboranes, can be used as hydrophobic pharmacophores in the design of new drugs and radiotracers because of…”
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Journal Article -
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Syntheses of Isoxazoline-Carbocyclic Nucleosides and Their Antiviral Evaluation: A Standard Protocol
Published in TheScientificWorld (2014)“…The current synthesis of racemic purine and pyrimidine isoxazoline-carbocyclic nucleosides is reported, detailing the key-steps for standard and reliable…”
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Journal Article -
8
Neural ECM and epilepsy
Published in Progress in brain research (2014)“…Currently, there are about 20 antiepileptic drugs on market. Still, seizures in about 30% of patients with epilepsy are not adequately controlled, or the drugs…”
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Journal Article -
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Evaluation of [18F]BR420 and [18F]BR351 as radiotracers for MMP‐9 imaging in colorectal cancer
Published in Journal of labelled compounds & radiopharmaceuticals (01-01-2017)“…MMP‐9 is a zinc‐dependent endopeptidase that is involved in the proteolytic degradation of the extracellular matrix and plays an important role in cancer…”
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Journal Article -
10
Synthesis and preclinical evaluation of an 18F labeled PDE7 inhibitor for PET neuroimaging
Published in Nuclear medicine and biology (01-12-2015)“…Phosphodiesterase 7 (PDE7) hydrolyzes selectively cyclic adenosine monophosphate (cAMP) which is an intracellular second messenger. PDE7 is expressed by 2…”
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Journal Article -
11
Synthesis and preclinical evaluation of an 18 F labeled PDE7 inhibitor for PET neuroimaging
Published in Nuclear medicine and biology (01-12-2015)Get full text
Journal Article -
12
Synthesis and preclinical evaluation of an super(18)F labeled PDE7 inhibitor for PET neuroimaging
Published in Nuclear medicine and biology (01-12-2015)“…Phosphodiesterase 7 (PDE7) hydrolyzes selectively cyclic adenosine mono-phosphate (cAMP) which is an intracellular second messenger. PDE7 is expressed by 2…”
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Journal Article -
13
Synthesis and preclinical evaluation of an18 F labeled PDE7 inhibitor for PET neuroimaging
Published in Nuclear medicine and biology (2015)“…Abstract Introduction Phosphodiesterase 7 (PDE7) hydrolyzes selectively cyclic adenosine monophosphate (cAMP) which is an intracellular second messenger. PDE7…”
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Journal Article -
14
Isoxazoline-carbocyclic aminols for nucleoside synthesis through aza-Diels–Alder reactions
Published in Tetrahedron (31-07-2006)“…A novel approach to useful aminols for the synthesis of carbocyclic nucleosides is reported starting from a convenient source, the 2-azanorborn-5-enes. These…”
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15
Palladium(0)-catalyzed syntheses of cyclopentenyl-nucleoside analogues
Published in ARKIVOC free online journal of organic chemistry (22-02-2009)Get full text
Journal Article -
16
Synthesis and in vivo evaluation of (11) C-labeled (1,7-dicarba-closo-dodecaboran-1-yl)-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}amide
Published in Journal of labelled compounds & radiopharmaceuticals (01-04-2014)“…Boron clusters, and especially dicarba-closo-dodecaboranes, can be used as hydrophobic pharmacophores in the design of new drugs and radiotracers because of…”
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Journal Article -
17
Synthesis and in vivo evaluation of 11 C‐labeled (1,7‐dicarba‐ closo ‐dodecaboran‐1‐yl)‐ N ‐{[(2 S )‐1‐ethylpyrrolidin‐2‐yl]methyl}amide
Published in Journal of labelled compounds & radiopharmaceuticals (01-04-2014)“…Boron clusters, and especially dicarba‐ closo ‐dodecaboranes, can be used as hydrophobic pharmacophores in the design of new drugs and radiotracers because of…”
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Journal Article -
18
Palladium(0)-catalyzed syntheses of cyclopentenyl-nucleoside analogues
Published in ARKIVOC (22-02-2009)Get full text
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