Search Results - "Vazir, Mukta"

The Panitumumab EGFR Complex Reveals a Binding Mechanism That Overcomes Cetuximab Induced Resistance by Sickmier, E Allen, Kurzeja, Robert J M, Michelsen, Klaus, Vazir, Mukta, Yang, Evelyn, Tasker, Andrew S

“…Panitumumab and cetuximab target the epidermal growth factor receptor for the treatment of metastatic colorectal cancer. These therapies provide a significant…”
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Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors by Lloyd, David J., St Jean, David J., Kurzeja, Robert J. M., Wahl, Robert C., Michelsen, Klaus, Cupples, Rod, Chen, Michelle, Wu, John, Sivits, Glenn, Helmering, Joan, Komorowski, Renée, Ashton, Kate S., Pennington, Lewis D., Fotsch, Christopher, Vazir, Mukta, Chen, Kui, Chmait, Samer, Zhang, Jiandong, Liu, Longbin, Norman, Mark H., Andrews, Kristin L., Bartberger, Michael D., Van, Gwyneth, Galbreath, Elizabeth J., Vonderfecht, Steven L., Wang, Minghan, Jordan, Steven R., Véniant, Murielle M., Hale, Clarence

“…Two small-molecule disruptors of the glucokinase–glucokinase-regulatory-protein complex, AMG-1694 and AMG-3969, are identified that decrease blood glucose…”
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Multiple transcription factors in 5'-flanking region of human polymeric Ig receptor control its basal expression by Solorzano-Vargas, R Sergio, Wang, Jiafang, Jiang, Lingling, Tsai, Hugh V, Ontiveros, Luis O, Vazir, Mukta A, Aguilera, Renato J, Martín, Martín G

“…The polymeric Ig receptor (pIgR) is a critical component of the mucosal immune system and is expressed in largest amounts in the small intestine. In this…”
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Generation of membrane proteins in polymer-based lipoparticles as flow cytometry antigens by Luna, V. Mitch, Vazir, Mukta, Vaish, Amit, Chong, Su, Chen, Irwin, Yamane, Harvey K.

“…[Display omitted] A major obstacle in the study of membrane proteins is the challenge in generating purified targets in a stable and native conformation…”
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Discovery of Small-Molecule Glucokinase Regulatory Protein Modulators That Restore Glucokinase Activity by Chen, Kui, Michelsen, Klaus, Kurzeja, Robert J M, Han, Joon, Vazir, Mukta, St Jean, Jr, David J, Hale, Clarence, Wahl, Robert C

“…In the nuclei of hepatocytes, glucokinase regulatory protein (GKRP) modulates the activity of glucokinase (GK), a key regulator of glucose homeostasis…”
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Role of passive and adaptive immunity in influencing enterocyte-specific gene expression by Jenkins, Shannon L, Wang, Jiafang, Vazir, Mukta, Vela, Jose, Sahagun, Omar, Gabbay, Peter, Hoang, Lisa, Diaz, Rosa L, Aranda, Richard, Martín, Martín G

“…Numerous genes expressed by intestinal epithelial cells are developmentally regulated, and the influence that adaptive (AI) and passive (PI) immunity have in…”
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Multiple transcription factors in the 5-flanking region of the human polymeric IgA receptor (pigR) controls its basal expression by Solorzano-Vargas, Sergio R., Wang, Jiafang, Jiang, Lingling, Hugh, Tsai V., Luis, Ontiveros O., Mukta, Vazir A., Renalto, Aguilera J., Martin, Martin G.

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