Search Results - "Vaz, Sara"
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FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence
Published in Nature communications (19-07-2018)“…Aneuploidy, an abnormal chromosome number, has been linked to aging and age-associated diseases, but the underlying molecular mechanisms remain unknown. Here…”
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Candidate Alzheimer's Disease Biomarker miR-483-5p Lowers TAU Phosphorylation by Direct ERK1/2 Repression
Published in International journal of molecular sciences (01-04-2021)“…MicroRNAs have been demonstrated as key regulators of gene expression in the etiology of a range of diseases including Alzheimer's disease (AD). Recently, we…”
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FOXM1 repression increases mitotic death upon antimitotic chemotherapy through BMF upregulation
Published in Cell death & disease (25-05-2021)“…Inhibition of spindle microtubule (MT) dynamics has been effectively used in cancer treatment. Although the mechanisms by which MT poisons elicit mitotic…”
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Sensitivity and Specificity of Spectral-Domain Optical Coherence Tomography in Detecting Idiopathic Polypoidal Choroidal Vasculopathy
Published in American journal of ophthalmology (01-12-2014)“…Purpose To evaluate the efficacy of spectral-domain optical coherence tomography (SD OCT) compared to indocyanine green angiography (ICGA) in detecting…”
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A Simplified Sanger Sequencing Method for Detection of Relevant SARS-CoV-2 Variants
Published in Diagnostics (Basel) (27-10-2022)“…Molecular surveillance of the new coronavirus through new genomic sequencing technologies revealed the circulation of important variants of SARS-CoV-2. Sanger…”
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Prevalence of severe acute respiratory syndrome coronavirus 2 in the saliva of individuals with coronavirus disease 2019: A cross-sectional study
Published in Journal of orofacial sciences (01-07-2023)“…Introduction: Saliva is involved in the transmission and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, there are conflicting…”
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Saliva is a reliable, non-invasive specimen for SARS-CoV-2 detection
Published in The Brazilian journal of infectious diseases (01-09-2020)“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of Coronavirus Disease 2019 (COVID-19). Although Real Time Reverse Transcription…”
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High Zika Virus Seroprevalence in Salvador, Northeastern Brazil Limits the Potential for Further Outbreaks
Published in mBio (14-11-2017)“…During 2015 to 2016, Brazil reported more Zika virus (ZIKV) cases than any other country, yet population exposure remains unknown. Serological studies of ZIKV…”
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Self-prescribed Ivermectin use is associated with a lower rate of seroconversion in health care workers diagnosed with COVID, in a dose-dependent response
Published in The Brazilian journal of infectious diseases (01-07-2021)“…Over-the-counter use of ivermectin amongst other drugs as SARS-CoV-2 treatment has been increasingly common, despite the lack of evidence on its clinical…”
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Chlorhexidine mouthwash reduces the salivary viral load of SARS‐CoV‐2: A randomized clinical trial
Published in Oral diseases (01-11-2022)“…Objectives This study aimed to evaluate the effect of 0.12% chlorhexidine gluconate on the salivary load of SARS‐CoV‐2. Materials and Methods A randomized,…”
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Skin and coeliac disease, a lot to think about: a case series
Published in BMJ case reports (04-01-2018)“…Coeliac disease (CD) is an autoimmune disease, characterised by a permanent sensitivity to gluten. It is being progressively recognised as a multisystemic…”
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Vascular endothelial growth factors and placenta growth factor in retinal vasculopathies: Current research and future perspectives
Published in Cytokine & growth factor reviews (01-02-2018)“…•A review of the function of growth factors VEGF-A, VEGF-B and PlGF in normal development and disease.•The implication of VEGF-A, VEGF-B and PlGF in the…”
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Challenges, facilitators and barriers to the adoption and use of a web-based national IRD registry: lessons learned from the IRD-PT registry
Published in Orphanet journal of rare diseases (26-08-2022)“…© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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Candida albicans commensalism in the oral mucosa is favoured by limited virulence and metabolic adaptation
Published in PLoS pathogens (11-04-2022)“…As part of the human microbiota, the fungus Candida albicans colonizes the oral cavity and other mucosal surfaces of the human body. Commensalism is tightly…”
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Optical coherence tomography angiography as a diagnostic tool to detect non-exudative neovascular membranes upon retinal pigmented epithelium irregularities and the shallow irregular retinal pigmented epithelium elevation sign
Published in Journal of Clinical Ophthalmology and Research (01-01-2024)“…Abstract Purpose: To highlight the high positive predictive value of the retinal pigmentary epithelium (RPE) irregularity and the shallow irregular retinal…”
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Optical coherence tomography features of neovascularization in proliferative diabetic retinopathy: a systematic review
Published in International journal of retina and vitreous (29-06-2020)“…Diabetic retinopathy (DR) is a leading cause of blindness due to diabetic macular edema (DME) or complications of proliferative diabetic retinopathy (PDR)…”
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Update on Optical Coherence Tomography and Optical Coherence Tomography Angiography Imaging in Proliferative Diabetic Retinopathy
Published in Diagnostics (Basel) (11-10-2021)“…Proliferative diabetic retinopathy (PDR) is a major cause of blindness in diabetic individuals. Optical coherence tomography (OCT) and OCT-angiography (OCTA)…”
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A unique phenotype in a patient with a rare triplication of the 22q11.2 region and new clinical insights of the 22q11.2 microduplication syndrome: a report of two cases
Published in BMC pediatrics (22-08-2015)“…The rearrangements of the 22q11.2 chromosomal region, most frequently deletions and duplications, have been known to be responsible for multiple congenital…”
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Validade e fiabilidade da versão portuguesa do Lymphoedema Quality of Life (LYMQOL) Leg
Published in Angiologia e cirurgia vascular (Sociedade Portuguesa de Angiologia e Cirurgia Vascular) (01-09-2022)“…Resumo Introdução: Os edemas crónicos dos membros inferiores são condições incuráveis, debilitantes e progressivas que causam problemas físicos, psicológicos e…”
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