Search Results - "Vaz, Bruno"

Survey on Synthetic Data Generation, Evaluation Methods and GANs by Figueira, Alvaro, Vaz, Bruno

“…Synthetic data consists of artificially generated data. When data are scarce, or of poor quality, synthetic data can be used, for example, to improve the…”
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Strategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication by Ramadan, Kristijan, Halder, Swagata, Wiseman, Katherine, Vaz, Bruno

“…Genome amplification (DNA synthesis) is one of the most demanding cellular processes in all proliferative cells. The DNA replication machinery (also known as…”
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Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair by Vaz, Bruno, Popovic, Marta, Newman, Joseph A., Fielden, John, Aitkenhead, Hazel, Halder, Swagata, Singh, Abhay Narayan, Vendrell, Iolanda, Fischer, Roman, Torrecilla, Ignacio, Drobnitzky, Neele, Freire, Raimundo, Amor, David J., Lockhart, Paul J., Kessler, Benedikt M., McKenna, Gillies W., Gileadi, Opher, Ramadan, Kristijan

“…The cytotoxicity of DNA-protein crosslinks (DPCs) is largely ascribed to their ability to block the progression of DNA replication. DPCs frequently occur in…”
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SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication by Halder, Swagata, Torrecilla, Ignacio, Burkhalter, Martin D., Popović, Marta, Fielden, John, Vaz, Bruno, Oehler, Judith, Pilger, Domenic, Lessel, Davor, Wiseman, Katherine, Singh, Abhay Narayan, Vendrell, Iolanda, Fischer, Roman, Philipp, Melanie, Ramadan, Kristijan

“…The SPRTN metalloprotease is essential for DNA-protein crosslink (DPC) repair and DNA replication in vertebrate cells. Cells deficient in SPRTN protease…”
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An altered redox balance mediates the hypersensitivity of Cockayne syndrome primary fibroblasts to oxidative stress by Pascucci, Barbara, Lemma, Tiziana, Iorio, Egidio, Giovannini, Sara, Vaz, Bruno, Iavarone, Ivano, Calcagnile, Angelo, Narciso, Laura, Degan, Paolo, Podo, Franca, Roginskya, Vera, Janjic, Bratislav M., Van Houten, Bennett, Stefanini, Miria, Dogliotti, Eugenia, D’Errico, Mariarosaria

“…Summary Cockayne syndrome (CS) is a rare hereditary multisystem disease characterized by neurological and development impairment, and premature aging. Cockayne…”
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UV-sensitive syndrome patient with a specific CSA mutation reveals separable roles for CSA in response to UV and oxidative DNA damage by Nardo, Tiziana, Oneda, Roberta, Spivak, Graciela, Vaz, Bruno, Mortier, Laurent, Thomas, Pierre, Orioli, Donata, Laugel, Vincent, Stary, Anne, Hanawalt, Philip C, Sarasin, Alain, Stefanini, Miria

“…UV-sensitive syndrome (UVSS) is a recently-identified autosomal recessive disorder characterized by mild cutaneous symptoms and defective transcription-coupled…”
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Clinical, Laboratory, and Imaging Profile in Patients with Systemic Amyloidosis in a Brazilian Cardiology Referral Center by Fernandes, Fábio, Alencar Neto, Aristóteles Comte de, Bueno, Bruno Vaz Kerges, Cafezeiro, Caio Rebouças Fonseca, Rissato, João Henrique, Szor, Roberta Shcolnik, Carvalho, Mariana Lombardi Peres de, Mathias Júnior, Wilson, Lino, Angelina Maria Martins, Castelli, Jussara Bianchi, Souza, Evandro de Oliveira, Ramires, Félix José Alvarez, Hotta, Viviane Tiemi, Soares Júnior, José, Tavares, Caio de Assis Moura, Krieger, José Eduardo, Rochitte, Carlos Eduardo, Dabarian, André, Hajjar, Ludhmila Abrahão, Kalil Filho, Roberto, Mady, Charles

“…Systemic amyloidosis is a disease with heterogeneous clinical manifestations. Diagnosis depends on clinical suspicion combined with specific complementary…”
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Aplication of videothoracoscopy in trauma - experience of a service by Melo, Bruno Vaz de, Siqueira, Felipe Guedes, Tano, Thales Siqueira Di, Silveira, Paulo Oliveira, Lima, Mariama Barroso de

“…Objective: To evaluate patients with chest trauma submitted to videothoracoscopy during hospitalization. In 2007, the Trauma Surgery Group was created in the…”
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Role of p97/VCP (Cdc48) in genome stability by Vaz, Bruno, Halder, Swagata, Ramadan, Kristijan

“…Ubiquitin-dependent molecular chaperone p97, also known as valosin-containing protein (VCP) or Cdc48, is an AAA ATPase involved in protein turnover and…”
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DNA–Protein Crosslink Proteolysis Repair by Vaz, Bruno, Popovic, Marta, Ramadan, Kristijan

“…Proteins that are covalently bound to DNA constitute a specific type of DNA lesion known as DNA–protein crosslinks (DPCs). DPCs represent physical obstacles to…”
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Perfil Clínico, Laboratorial e de Métodos de Imagem na Amiloidose Sistêmica em um Centro de Referência Cardiológico Brasileiro by Fernandes, Fábio, Alencar, Aristóteles Comte de, Bueno, Bruno Vaz Kerges, Cafezeiro, Caio Rebouças Fonseca, Rissato, João Henrique, Szor, Roberta Shcolnik, Carvalho, Mariana Lombardi Peres de, Mathias, Wilson, Lino, Angelina Maria Martins, Castelli, Jussara Bianchi, Souza, Evandro de Oliveira, Ramires, Félix José Alvarez, Hotta, Viviane Tiemi, Soares, José, Tavares, Caio de Assis Moura, Krieger, José Eduardo, Rochitte, Carlos Eduardo, Dabarian, André, Hajjar, Ludhmila Abrahão, Kalil, Roberto, Mady, Charles

“…Resumo Fundamento Amiloidose sistêmica é uma doença com manifestações clínicas diversas. O diagnóstico envolve suspeita clínica, aliada a métodos…”
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TRANSPLANTE HEPÁTICO NA INSUFICIÊNCIA HEPÁTICA AGUDA GRAVE INDUZIDA POR IMATINIBE by Rezende, Danilo Nakaya Alvarenga de, Romano, Natalia Campregher Confuorto, Martinho, Gabriela Tomaz, Antunes, Pedro de Souza Lucarelli, Santi, Talita Di, Fantauzzi, Marcelo Callado, Bueno, Bruno Vaz Kerges, David, André Ibrahim

“…AMM, sexo feminino, 40 anos, portadora de leucemia mieloide crônica (LMC), em uso de Imanitibe 400 mg/dia desde o diagnóstico da doença, em 13/06/2016; foi…”
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An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory by Lanna, Alessio, Vaz, Bruno, D’Ambra, Clara, Valvo, Salvatore, Vuotto, Claudia, Chiurchiù, Valerio, Devine, Oliver, Sanchez, Massimo, Borsellino, Giovanna, Akbar, Arne N., De Bardi, Marco, Gilroy, Derek W., Dustin, Michael L., Blumer, Brendan, Karin, Michael

“…The common view is that T lymphocytes activate telomerase to delay senescence. Here we show that some T cells (primarily naïve and central memory cells)…”
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TRANSPLANTE HEPÁTICO NA POLIAMILOIDOSE FAMILIAR: RELATO DE CASO by Martinho, Gabriela Tomaz, Antunes, Pedro de Souza Lucarelli, Santi, Talita Di, Rezende, Danilo Nakaya Alvarenga de, Romano, Natalia Campregher Confuorto, Fantauzzi, Marcelo Callado, Bueno, Bruno Vaz Kerges, David, Andre Ibrahim

“…  Objetivo: Relatar um caso de transplante hepático em paciente portadora de Cardiopatia Amiloide Familiar (Transtirretina). O transplante de fígado é um…”
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CLINICAL, ECHOCARDIOGRAPHIC CHARACTERISTICS AND PROGNOSTIC IMPORTANCE OF THE WALKING TEST IN PATIENTS WITH ATTR CARDIAC AMYLOIDOSIS by Romero, Cristhian Espinoza, PEREIRA, NATALIA, DEL CISNE JADÁN LUZURIAGA, GEORGINA, Bueno, Bruno Vaz Kerges, Carvalhal, Suenia, Borges, Thais, Reis, Barbara, Fernandes, Fabio

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Wip1 downregulation conserves truncated DNA damage response (DDR) in mitosis by Vaz, Bruno, Ramadan, Kristijan

“…Comment on: Macurek L, et al. Cell Cycle 2012; 12:251-62…”
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The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability by Ruggiano, Annamaria, Vaz, Bruno, Kilgas, Susan, Popović, Marta, Rodriguez-Berriguete, Gonzalo, Singh, Abhay N., Higgins, Geoff S., Kiltie, Anne E., Ramadan, Kristijan

“…DNA-protein crosslinks (DPCs) are a specific type of DNA lesion in which proteins are covalently attached to DNA. Unrepaired DPCs lead to genomic instability,…”
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The CUBES Science Case by Evans, Chris, Cristiani, Stefano, Opitom, Cyrielle, Cescutti, Gabriele, D'Odorico, Valentina, Alcalá, Juan Manuel, Alencar, Silvia H. P, Balashev, Sergei, Barbuy, Beatriz, Bastian, Nate, Battino, Umberto, Cambianica, Pamela, Carini, Roberta, Carter, Brad, Cassisi, Santi, Castilho, Bruno Vaz, Christlieb, Norbert, Cooke, Ryan, Covino, Stefano, Cremonese, Gabriele, Cunha, Katia, da Silva, André R, D'Elia, Valerio, De Cia, Annalisa, De Silva, Gayandhi, Diaz, Marcos, Di Marcantonio, Paolo, Ernandes, Heitor, Fitzsimmons, Alan, Franchini, Mariagrazia, Gänsicke, Boris T, Genoni, Matteo, Giribaldi, Riano E, Grazian, Andrea, Hansen, Camilla Juul, La Forgia, Fiorangela, Lazzarin, Monica, Marcolino, Wagner, Marconi, Marcella, Migliorini, Alessandra, Noterdaeme, Pasquier, Pereira, Claudio, Pilecki, Bogumil, Quirrenbach, Andreas, Randich, Sofia, Rossi, Silvia, Smiljanic, Rodolfo, Snodgrass, Colin, Stürmer, Julian, Trost, Andrea, Vanzella, Eros, Ventura, Paolo, Wright, Duncan, Zafar, Tayyaba

“…We introduce the scientific motivations for the development of the Cassegrain U-Band Efficient Spectrograph (CUBES) that is now in construction for the Very…”
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Detailed Analysis of Nearby Bulgelike Dwarf Stars. II. Lithium Abundances by Pompéia, Luciana, Barbuy, Beatriz, Grenon, Michel, Castilho, Bruno Vaz

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Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation by Lanzafame, Manuela, Branca, Giulia, Landi, Claudia, Qiang, Mingyue, Vaz, Bruno, Nardo, Tiziana, Ferri, Debora, Mura, Manuela, Iben, Sebastian, Stefanini, Miria, Peverali, Fiorenzo A, Bini, Luca, Orioli, Donata

“…Abstract CSA and CSB proteins are key players in transcription-coupled nucleotide excision repair (TC-NER) pathway that removes UV-induced DNA lesions from the…”
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