Search Results - "Vayndorf, Elena M"

Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models by Maulik, Malabika, Mitra, Swarup, Bult-Ito, Abel, Taylor, Barbara E, Vayndorf, Elena M

“…Parkinson's disease (PD) is a neurodegenerative disorder with symptoms that progressively worsen with age. Pathologically, PD is characterized by the…”
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Whole apple extracts increase lifespan, healthspan and resistance to stress in Caenorhabditis elegans by Vayndorf, Elena M, Lee, Siu Sylvia, Liu, Rui Hai

“…Regular consumption of fruits and vegetables is associated with reduced risk of age-related functional decline and chronic diseases such as cancer and…”
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Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons by Scerbak, Courtney, Vayndorf, Elena M, Parker, J Alex, Neri, Christian, Driscoll, Monica, Taylor, Barbara E

“…Insulin signaling is central to cellular metabolism and organismal aging. However, the role of insulin signaling in natural and proteotoxically stressed aging…”
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Mechanosensory Neuron Aging: Differential Trajectories with Lifespan-Extending Alaskan Berry and Fungal Treatments in Caenorhabditis elegans by Scerbak, Courtney, Vayndorf, Elena M, Hernandez, Alicia, McGill, Colin, Taylor, Barbara E

“…Many nutritional interventions that increase lifespan are also proposed to postpone age-related declines in motor and cognitive function. Potential sources of…”
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WormBot, an open-source robotics platform for survival and behavior analysis in C. elegans by Pitt, Jason N., Strait, Nolan L., Vayndorf, Elena M., Blue, Benjamin W., Tran, Christina H., Davis, Brendon E. M., Huang, Karen, Johnson, Brock J., Lim, Keong Mu, Liu, Sophie, Nikjoo, Arash, Vaid, Anuj, Wu, Judy Z., Kaeberlein, Matt

“…Caenorhabditis elegans is a popular organism for aging research owing to its highly conserved molecular pathways, short lifespan, small size, and extensive…”
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Evidence that conserved essential genes are enriched for pro-longevity factors by Oz, Naci, Vayndorf, Elena M., Tsuchiya, Mitsuhiro, McLean, Samantha, Turcios-Hernandez, Lesly, Pitt, Jason N., Blue, Benjamin W., Muir, Michael, Kiflezghi, Michael G., Tyshkovskiy, Alexander, Mendenhall, Alexander, Kaeberlein, Matt, Kaya, Alaattin

“…At the cellular level, many aspects of aging are conserved across species. This has been demonstrated by numerous studies in simple model organisms like…”
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Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age by Molière, Adrian, Park, Ji Young Cecilia, Goyala, Anita, Vayndorf, Elena M., Zhang, Bruce, Hsiung, Kuei Ching, Jung, Yoonji, Kwon, Sujeong, Statzer, Cyril, Meyer, David, Nguyen, Richard, Chadwick, Joseph, Thompson, Maximilian A., Schumacher, Björn, Lee, Seung-Jae V., Essmann, Clara L., MacArthur, Michael R., Kaeberlein, Matt, David, Della, Gems, David, Ewald, Collin Y.

“…Little is known about the possibility of reversing age-related biological changes when they have already occurred. To explore this, we have characterized the…”
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Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis by Vayndorf, Elena M, Scerbak, Courtney, Hunter, Skyler, Neuswanger, Jason R, Toth, Marton, Parker, J Alex, Neri, Christian, Driscoll, Monica, Taylor, Barbara E

“…Understanding cellular outcomes, such as neuronal remodeling, that are common to both healthy and diseased aging brains is essential to the development of…”
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