Search Results - "Vayndorf, Elena"

Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models by Maulik, Malabika, Mitra, Swarup, Bult-Ito, Abel, Taylor, Barbara E, Vayndorf, Elena M

“…Parkinson's disease (PD) is a neurodegenerative disorder with symptoms that progressively worsen with age. Pathologically, PD is characterized by the…”
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Whole apple extracts increase lifespan, healthspan and resistance to stress in Caenorhabditis elegans by Vayndorf, Elena M, Lee, Siu Sylvia, Liu, Rui Hai

“…Regular consumption of fruits and vegetables is associated with reduced risk of age-related functional decline and chronic diseases such as cancer and…”
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Mechanosensory Neuron Aging: Differential Trajectories with Lifespan-Extending Alaskan Berry and Fungal Treatments in Caenorhabditis elegans by Scerbak, Courtney, Vayndorf, Elena M, Hernandez, Alicia, McGill, Colin, Taylor, Barbara E

“…Many nutritional interventions that increase lifespan are also proposed to postpone age-related declines in motor and cognitive function. Potential sources of…”
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WormBot, an open-source robotics platform for survival and behavior analysis in C. elegans by Pitt, Jason N., Strait, Nolan L., Vayndorf, Elena M., Blue, Benjamin W., Tran, Christina H., Davis, Brendon E. M., Huang, Karen, Johnson, Brock J., Lim, Keong Mu, Liu, Sophie, Nikjoo, Arash, Vaid, Anuj, Wu, Judy Z., Kaeberlein, Matt

“…Caenorhabditis elegans is a popular organism for aging research owing to its highly conserved molecular pathways, short lifespan, small size, and extensive…”
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Evidence that conserved essential genes are enriched for pro-longevity factors by Oz, Naci, Vayndorf, Elena M., Tsuchiya, Mitsuhiro, McLean, Samantha, Turcios-Hernandez, Lesly, Pitt, Jason N., Blue, Benjamin W., Muir, Michael, Kiflezghi, Michael G., Tyshkovskiy, Alexander, Mendenhall, Alexander, Kaeberlein, Matt, Kaya, Alaattin

“…At the cellular level, many aspects of aging are conserved across species. This has been demonstrated by numerous studies in simple model organisms like…”
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Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age by Molière, Adrian, Park, Ji Young Cecilia, Goyala, Anita, Vayndorf, Elena M., Zhang, Bruce, Hsiung, Kuei Ching, Jung, Yoonji, Kwon, Sujeong, Statzer, Cyril, Meyer, David, Nguyen, Richard, Chadwick, Joseph, Thompson, Maximilian A., Schumacher, Björn, Lee, Seung-Jae V., Essmann, Clara L., MacArthur, Michael R., Kaeberlein, Matt, David, Della, Gems, David, Ewald, Collin Y.

“…Little is known about the possibility of reversing age-related biological changes when they have already occurred. To explore this, we have characterized the…”
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Corrigendum: Mechanosensory Neuron Aging: Differential Trajectories with Lifespan-Extending Alaskan Berry and Fungal Treatments in Caenorhabditis elegans by Scerbak, Courtney, Vayndorf, Elena, Hernandez, Alicia, McGill, Colin, Taylor, Barbara

“…[This corrects the article on p. 173 in vol. 8, PMID: 27486399.]…”
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Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons by Scerbak, Courtney, Vayndorf, Elena M, Parker, J Alex, Neri, Christian, Driscoll, Monica, Taylor, Barbara E

“…Insulin signaling is central to cellular metabolism and organismal aging. However, the role of insulin signaling in natural and proteotoxically stressed aging…”
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Taurine deficiency as a driver of aging by Singh, Parminder, Gollapalli, Kishore, Mangiola, Stefano, Schranner, Daniela, Yusuf, Mohd Aslam, Chamoli, Manish, Shi, Sting L, Lopes Bastos, Bruno, Nair, Tripti, Riermeier, Annett, Vayndorf, Elena M, Wu, Judy Z, Nilakhe, Aishwarya, Nguyen, Christina Q, Muir, Michael, Kiflezghi, Michael G, Foulger, Anna, Junker, Alex, Devine, Jack, Sharan, Kunal, Chinta, Shankar J, Rajput, Swati, Rane, Anand, Baumert, Philipp, Schönfelder, Martin, Iavarone, Francescopaolo, di Lorenzo, Giorgia, Kumari, Swati, Gupta, Alka, Sarkar, Rajesh, Khyriem, Costerwell, Chawla, Amanpreet S, Sharma, Ankur, Sarper, Nazan, Chattopadhyay, Naibedya, Biswal, Bichitra K, Settembre, Carmine, Nagarajan, Perumal, Targoff, Kimara L, Picard, Martin, Gupta, Sarika, Velagapudi, Vidya, Papenfuss, Anthony T, Kaya, Alaattin, Ferreira, Miguel Godinho, Kennedy, Brian K, Andersen, Julie K, Lithgow, Gordon J, Ali, Abdullah Mahmood, Mukhopadhyay, Arnab, Palotie, Aarno, Kastenmüller, Gabi, Kaeberlein, Matt, Wackerhage, Henning, Pal, Bhupinder, Yadav, Vijay K

“…Aging is associated with changes in circulating levels of various molecules, some of which remain undefined. We find that concentrations of circulating taurine…”
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Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment by Chng, Kern Rei, Li, Chenhao, Bertrand, Denis, Ng, Amanda Hui Qi, Kwah, Junmei Samantha, Low, Hwee Meng, Tong, Chengxuan, Natrajan, Maanasa, Zhang, Michael Hongjie, Xu, Licheng, Ko, Karrie Kwan Ki, Ho, Eliza Xin Pei, Av-Shalom, Tamar V., Teo, Jeanette Woon Pei, Khor, Chiea Chuen, Chen, Swaine L., Mason, Christopher E., Ng, Oon Tek, Marimuthu, Kalisvar, Ang, Brenda, Nagarajan, Niranjan

“…Although disinfection is key to infection control, the colonization patterns and resistomes of hospital-environment microbes remain underexplored. We report…”
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Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis by Vayndorf, Elena M, Scerbak, Courtney, Hunter, Skyler, Neuswanger, Jason R, Toth, Marton, Parker, J Alex, Neri, Christian, Driscoll, Monica, Taylor, Barbara E

“…Understanding cellular outcomes, such as neuronal remodeling, that are common to both healthy and diseased aging brains is essential to the development of…”
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Pharyngeal Pumping in the Nematode C. elegans: Resolving Treatment Effects through Variability Assessment by Ortiz, Brianna, Hincks, Joshua, Vayndorf, Elena, Taylor, Barbara E., Harris, Michael B.

“…In C. elegans, feeding is achieved through a well characterized behavior, pharyngeal pumping. This pumping is controlled by two pairs of pharyngeal motor…”
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LONGEVITY OVER THE COUNTER: INVESTIGATING THE EFFECTS OF COMMON DIETARY SUPPLEMENTS ON AGING by Blue, Ben, Vayndorf, Elena, Kaeberlein, Matt

“…C. elegans has been a workhorse within the field of aging biology for several decades due to its short lifespan, easy culturing, and robust genetic tools…”
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Alaskan Botanicals Influence Neuronal Aging by Scerbak, Courtney, Vayndorf, Elena, McGill, Colin, Taylor, Barbara

“…Abstract only Aging is a risk factor for many life‐threatening disorders, including neurodegenerative diseases. Many genetic mutations and environmental…”
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Alaskan berry treatments maintain C. elegans motility and sarcomere integrity with age by Touray, Farimang, Maulik, Malabika, Scerbak, Courtney, Vayndorf, Elena, Ito, Abel Bult, Taylor, Barbara

“…Abstract only Maintaining health with age is a major health concern due to loss of muscle mass, locomotion and increased likelihood of developing…”
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Lowbush cranberry acts through DAF-16/FOXO signaling to promote increased lifespan and axon branching in aging posterior touch receptor neurons by Scerbak, Courtney, Vayndorf, Elena, Hernandez, Alicia, McGill, Colin, Taylor, Barbara

“…Medicinal berries are appreciated for their health benefits, in traditional ecological knowledge and nutrition science. Determining the cellular mechanisms…”
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Evidence of age‐related neuronal aberrations and dysfunction of sensory neurons in a polyglutamine model of Huntington's disease by Vayndorf, Elena, Driscoll, Monica, Taylor, Barbara

“…Abstract only Huntington's disease is a neurodegenerative disorder that impairs motor movements and cognitive ability. It is caused by expansion of the CAG…”
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Caenorhabditis Sieve: A Low-tech Instrument and Methodology for Sorting Small Multicellular Organisms by Hunter, Skyler, Maulik, Malabika, Scerbak, Courtney, Vayndorf, Elena, Taylor, Barbara E

“…Caenorhabditis elegans (C. elegans) is a well-established model organism used across a range of basic and biomedical research. Within the nematode research…”
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A ROBOTIC SYSTEM FOR HIGH-THROUGHPUT AUTOMATED LIFESPAN ANALYSIS IN C. ELEGANS by Blue, Ben, Vayndorf, Elena, Kaeberlein, Matt, Pitt, Jason

“…Over the past decade, the identification of potential genetic and pharmacological modifiers of lifespan and age-related pathologies in C. elegans and other…”
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Caenorhabditis Sieve: A Low-tech Instrument and Methodology for Sorting Small Multicellular Organisms by Hunter, Skyler, Maulik, Malabika, Scerbak, Courtney, Vayndorf, Elena, Taylor, Barbara E.

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