Search Results - "Vawter, MP"

Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry by Bigdeli, Tim B., Genovese, Giulio, Georgakopoulos, Penelope, Meyers, Jacquelyn L., Peterson, Roseann E., Iyegbe, Conrad O., Medeiros, Helena, Valderrama, Jorge, Achtyes, Eric D., Kotov, Roman, Stahl, Eli A., Abbott, Colony, Azevedo, Maria Helena, Belliveau, Richard A., Bevilacqua, Elizabeth, Bromet, Evelyn J., Byerley, William, Carvalho, Celia Barreto, Chapman, Sinéad B., DeLisi, Lynn E., Dumont, Ashley L., O’Dushlaine, Colm, Evgrafov, Oleg V., Fochtmann, Laura J., Gage, Diane, Kennedy, James L., Kinkead, Becky, Macedo, Antonio, Moran, Jennifer L., Morley, Christopher P., Dewan, Mantosh J., Nemesh, James, Perkins, Diana O., Purcell, Shaun M., Rakofsky, Jeffrey J., Scolnick, Edward M., Sklar, Brooke M., Sklar, Pamela, Smoller, Jordan W., Sullivan, Patrick F., Macciardi, Fabio, Marder, Stephen R., Gur, Ruben C., Gur, Raquel E., Braff, David L., Nicolini, Humberto, Escamilla, Michael A., Vawter, Marquis P., Sobell, Janet L., Malaspina, Dolores, Lehrer, Douglas S., Buckley, Peter F., Rapaport, Mark H., Knowles, James A., Fanous, Ayman H., Pato, Michele T., McCarroll, Steven A., Pato, Carlos N.

“…Schizophrenia is a common, chronic and debilitating neuropsychiatric syndrome affecting tens of millions of individuals worldwide. While rare genetic variants…”
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Identification of pathways for bipolar disorder: a meta-analysis by Nurnberger, Jr, John I, Koller, Daniel L, Jung, Jeesun, Edenberg, Howard J, Foroud, Tatiana, Guella, Ilaria, Vawter, Marquis P, Kelsoe, John R

“…Genome-wide investigations provide systematic information regarding the neurobiology of psychiatric disorders. To identify biological pathways that contribute…”
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Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder by Bunney, B G, Li, J Z, Walsh, D M, Stein, R, Vawter, M P, Cartagena, P, Barchas, J D, Schatzberg, A F, Myers, R M, Watson, S J, Akil, H, Bunney, W E

“…Conventional antidepressants require 2–8 weeks for a full clinical response. In contrast, two rapidly acting antidepressant interventions, low-dose ketamine…”
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The KMO allele encoding Arg 452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression by Lavebratt, C, Olsson, S, Backlund, L, Frisen, L, Sellgren, C, Priebe, L, Nikamo, P, Traskman-Bendz, L, Cichon, S, Vawter, MP

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The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression by Lavebratt, C, Olsson, S, Backlund, L, Frisén, L, Sellgren, C, Priebe, L, Nikamo, P, Träskman-Bendz, L, Cichon, S, Vawter, M P, Ösby, U, Engberg, G, Landén, M, Erhardt, S, Schalling, M

“…The kynurenine pathway metabolite kynurenic acid (KYNA), modulating glutamatergic and cholinergic neurotransmission, is increased in cerebrospinal fluid (CSF)…”
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A Comprehensive Analysis of Nuclear-Encoded Mitochondrial Genes in Schizophrenia by Gonçalves, Vanessa F., Cappi, Carolina, Hagen, Christian M., Sequeira, Adolfo, Vawter, Marquis P., Derkach, Andriy, Zai, Clement C., Hedley, Paula L., Bybjerg-Grauholm, Jonas, Pouget, Jennie G., Cuperfain, Ari B., Sullivan, Patrick F., Christiansen, Michael, Kennedy, James L., Sun, Lei

“…The genetic risk factors of schizophrenia (SCZ), a severe psychiatric disorder, are not yet fully understood. Multiple lines of evidence suggest that…”
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A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder by Sellgren, C M, Kegel, M E, Bergen, S E, Ekman, C J, Olsson, S, Larsson, M, Vawter, M P, Backlund, L, Sullivan, P F, Sklar, P, Smoller, J W, Magnusson, P K E, Hultman, C M, Walther-Jallow, L, Svensson, C I, Lichtenstein, P, Schalling, M, Engberg, G, Erhardt, S, Landén, M

“…Elevated cerebrospinal fluid (CSF) levels of the glia-derived N -methyl- D -aspartic acid receptor antagonist kynurenic acid (KYNA) have consistently been…”
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Altered Cortical Glutamatergic and GABAergic Signal Transmission with Glial Involvement in Depression by Choudary, P. V., Molnar, M., Evans, S. J., Tomita, H., Li, J. Z., Vawter, M. P., Myers, R. M., W. E. Bunney, Jr, Akil, H., Watson, S. J., Jones, E. G.

“…Abnormalities in L-glutamic acid (glutamate) and GABA signal transmission have been postulated to play a role in depression, but little is known about the…”
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GRK3 deficiency elicits brain immune activation and psychosis by Sellgren, Carl M., Imbeault, Sophie, Larsson, Markus K., Oliveros, Alfredo, Nilsson, Ida A. K., Codeluppi, Simone, Orhan, Funda, Bhat, Maria, Tufvesson-Alm, Maximilian, Gracias, Jessica, Kegel, Magdalena E., Zheng, Yiran, Faka, Anthi, Svedberg, Marie, Powell, Susan B., Caldwell, Sorana, Kamenski, Mary E., Vawter, Marquis P., Schulmann, Anton, Goiny, Michel, Svensson, Camilla I., Hökfelt, Tomas, Schalling, Martin, Schwieler, Lilly, Cervenka, Simon, Choi, Doo-Sup, Landén, Mikael, Engberg, Göran, Erhardt, Sophie

“…The G protein-coupled receptor kinase (GRK) family member protein GRK3 has been linked to the pathophysiology of schizophrenia and bipolar disorder…”
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Analysis of Microarray Data Using Z Score Transformation by Cheadle, Chris, Vawter, Marquis P., Freed, William J., Becker, Kevin G.

“…High-throughput cDNA microarray technology allows for the simultaneous analysis of gene expression levels for thousands of genes and as such, rapid, relatively…”
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Correction: GRK3 deficiency elicits brain immune activation and psychosis by Sellgren, Carl M., Imbeault, Sophie, Larsson, Markus K., Oliveros, Alfredo, Nilsson, Ida A. K., Codeluppi, Simone, Orhan, Funda, Bhat, Maria, Tufvesson-Alm, Maximilian, Gracias, Jessica, Kegel, Magdalena E., Zheng, Yiran, Faka, Anthi, Svedberg, Marie, Powell, Susan B., Caldwell, Sorana, Kamenski, Mary E., Vawter, Marquis P., Schulmann, Anton, Goiny, Michel, Svensson, Camilla I., Hökfelt, Tomas, Schalling, Martin, Schwieler, Lilly, Cervenka, Simon, Choi, Doo-Sup, Landén, Mikael, Engberg, Göran, Erhardt, Sophie

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Examining the role of common and rare mitochondrial variants in schizophrenia by Gonçalves, Vanessa F, Giamberardino, Stephanie N, Crowley, James J, Vawter, Marquis P, Saxena, Richa, Bulik, Cynthia M, Yilmaz, Zeynep, Hultman, Christina M, Sklar, Pamela, Kennedy, James L, Sullivan, Patrick F, Knight, Jo

“…Oxidative phosphorylation within mitochondria is the main source of aerobic energy for neuronal functioning, and the key genes are located in mitochondrial…”
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CRY2 is associated with depression by Lavebratt, Catharina, Sjöholm, Louise K, Soronen, Pia, Paunio, Tiina, Vawter, Marquis P, Bunney, William E, Adolfsson, Rolf, Forsell, Yvonne, Wu, Joseph C, Kelsoe, John R, Partonen, Timo, Schalling, Martin

“…Abnormalities in the circadian clockwork often characterize patients with major depressive and bipolar disorders. Circadian clock genes are targets of interest…”
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Dysregulation of the Fibroblast Growth Factor System in Major Depression by Evans, S. J., Choudary, P. V., Neal, C. R., Li, J. Z., Vawter, M. P., Tomita, H., Lopez, J. F., Thompson, R. C., Meng, F., Stead, J. D., Walsh, D. M., Myers, R. M., Bunney, W. E., Watson, S. J., Jones, E. G., Akil, H.

“…In this report we describe findings that imply dysregulation of several fibroblast growth factor (FGF) system transcripts in frontal cortical regions of brains…”
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Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain by Tomita, Hiroaki, Vawter, Marquis P, Walsh, David M, Evans, Simon J, Choudary, Prabhakara V, Li, Jun, Overman, Kevin M, Atz, Mary E, Myers, Richard M, Jones, Edward G, Watson, Stanley J, Akil, Huda, Bunney, William E

“…There are major concerns that specific agonal conditions, including coma and hypoxia, might affect ribonucleic acid (RNA) integrity in postmortem brain…”
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Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders by VAWTER, M. P, TOMITA, H, WALSH, D. M, BURMEISTER, M, SPEED, T, MYERS, R, JONES, E. G, WATSON, S. J, AKIL, H, BUNNEY, W. E, MENG, F, BOLSTAD, B, LI, J, EVANS, S, CHOUDARY, P, ATZ, M, SHAO, L, NEAL, C

“…Mitochondrial defects in gene expression have been implicated in the pathophysiology of bipolar disorder and schizophrenia. We have now contrasted control…”
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Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study by Vawter, Marquis P, Crook, Jeremy M, Hyde, Thomas M, Kleinman, Joel E, Weinberger, Daniel R, Becker, Kevin G, Freed, William J

“…Microarray studies can be used to examine expression levels for large numbers of genes simultaneously and may be applied to identify genes involved in…”
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Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions by Li, Jun Z., Vawter, Marquis P., Walsh, David M., Tomita, Hiroaki, Evans, Simon J., Choudary, Prabhakara V., Lopez, Juan F., Avelar, Abigail, Shokoohi, Vida, Chung, Tisha, Mesarwi, Omar, Jones, Edward G., Watson, Stanley J., Akil, Huda, Bunney, William E., Myers, Richard M.

“…Studies of gene expression abnormalities in psychiatric or neurological disorders often involve the use of postmortem brain tissue. Compared with single-cell…”
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Microarray screening of lymphocyte gene expression differences in a multiplex schizophrenia pedigree by Vawter, Marquis P, Ferran, Erick, Galke, Brandi, Cooper, Kathleen, Bunney, William E, Byerley, William

“…In order to help prioritize the selection of candidate genes and to study possible trait and not state related changes in gene expression, we compared…”
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P2RX7: expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1 by Backlund, Lena, Lavebratt, Catharina, Frisén, Louise, Nikamo, Pernilla, Hukic Sudic, Dzana, Träskman-Bendz, Lil, Landén, Mikael, Edman, Gunnar, Vawter, Marquis P, Ösby, Urban, Schalling, Martin

“…Rapid cycling is a severe form of bipolar disorder with an increased rate of episodes that is particularly treatment-responsive to chronotherapy and stable…”
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