Search Results - "Vavilin, Valentin A"

Design, Synthesis and Assay of Novel Methylxanthine-Alkynylmethylamine Derivatives as Acetylcholinesterase Inhibitors by Reshetnikov, Danila V, Ivanov, Igor D, Baev, Dmitry S, Rybalova, Tatyana V, Mozhaitsev, Evgenii S, Patrushev, Sergey S, Vavilin, Valentin A, Tolstikova, Tatyana G, Shults, Elvira E

“…Xanthine derivatives have been a great area of interest for the development of potent bioactive agents. Thirty-eight methylxanthine derivatives as…”
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Hybrides of Alkaloid Lappaconitine with Pyrimidine Motif on the Anthranilic Acid Moiety: Design, Synthesis, and Investigation of Antinociceptive Potency by Cheremnykh, Kirill P, Savelyev, Victor A, Borisov, Sergey A, Ivanov, Igor D, Baev, Dmitry S, Tolstikova, Tatyana G, Vavilin, Valentin A, Shults, Elvira E

“…Convenient and efficient routes to construct hybrid molecules containing diterpene alkaloid lappaconitine and pyrimidine fragments are reported. One route…”
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Functional Analysis of the Unique Cytochrome P450 of the Liver Fluke Opisthorchis felineus by Pakharukova, Mariya Y, Vavilin, Valentin A, Sripa, Banchob, Laha, Thewarach, Brindley, Paul J, Mordvinov, Viatcheslav A

“…The basic metabolic cytochrome P450 (CYP) system is essential for biotransformation of sterols and xenobiotics including drugs, for synthesis and degradation…”
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The gene expression profile of a drug metabolism system and signal transduction pathways in the liver of mice treated with tert-butylhydroquinone or 3-(3'-tert-butyl-4'-hydroxyphenyl)propylthiosulfonate of sodium by Shintyapina, Alexandra B, Vavilin, Valentin A, Safronova, Olga G, Lyakhovich, Vyacheslav V

“…Tert-butylhydroquinone (tBHQ) is a highly effective phenolic antioxidant used in edible oils and fats in foods as well as in medicines and cosmetics. TBHQ has…”
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Trehalose Activates Hepatic and Myocardial Autophagy and Has Anti-Inflammatory Effects in db / db Diabetic Mice by Korolenko, Tatiana A, Ovsyukova, Marina V, Bgatova, Nataliya P, Ivanov, Igor D, Makarova, Svetlana I, Vavilin, Valentin A, Popov, Alexey V, Yuzhik, Ekaterina I, Koldysheva, Elena V, Korolenko, Erik C, Zavjalov, Evgeny L, Amstislavskaya, Tamara G

“…mice (carrying a mutation in the gene encoding leptin receptor) show autophagy suppression. Our aim was to evaluate the effect of autophagy inducer trehalose…”
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Mitochondrial Dysfunction as a Predictor and Driver of Alzheimer's Disease-Like Pathology in OXYS Rats by Tyumentsev, Mikhail A, Stefanova, Natalia A, Muraleva, Natalia A, Rumyantseva, Yulia V, Kiseleva, Elena, Vavilin, Valentin A, Kolosova, Nataliya G

“…Growing evidence suggests that mitochondrial dysfunction is an early event in sporadic Alzheimer's disease (AD), but the impact of mitochondrial dysfunction on…”
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Blessed are the meek for they shall inherit the earth: quietness component of introversion is associated with single nucleotide polymorphisms in two circadian clock genes by Putilov, Arcady A., Ivanov, Igor D., Nechunaev, Victor V., Vavilin, Valentin A.

“…Individual differences studied by chronobiologists and personality psychologists are usually shaped by polygenic selection occurring by small allele frequency…”
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Introversion and a single nucleotide polymorphism in PER3 gene: demure female students prevail among carriers of the rare allele by Putilov, Arcady A., Nechunaev, Victor V., Ivanov, Igor D., Popov, Alexey V., Vavilin, Valentin A.

“…Genetic basis and evolutionary mechanisms responsible for maintaining variation in broad personality traits remain the mysteries. Recently, Extraversion that…”
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A pilot replication study of two PER3 single nucleotide polymorphisms as potential genetic markers for morning and evening earliness-lateness by Dorokhov, Vladimir B., Puchkova, Alexandra N, Taranov, Anton O., Slominsky, Petr A., Vavilin, Valentin A., Ivanov, Igor D., Popov, Alexey V., Nechunaev, Victor V., Aǐzman, Roman I., Budkevich, Elena V., Budkevich, Roman O., Donskaya, Olga G., Putilov, Arcady A.

“…Polymorphisms in genes of circadian system family seem to be of most importance for understanding of mechanisms underlying self-assessed individual variation…”
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An hour in the morning is worth two in the evening: association of morning component of morningness–eveningness with single nucleotide polymorphisms in circadian clock genes by Dorokhov, Vladimir B., Puchkova, Alexandra N., Taranov, Anton O., Slominsky, Petr A., Tupitsina, Tatiana V., Ivanov, Igor D., Vavilin, Valentin A., Nechunaev, Victor V., Kolomeichuk, Sergey N., Morozov, Artem V., Budkevich, Elena V., Budkevich, Roman O., Dementienko, Valeriy V., Sveshnikov, Dmitry S., Donskaya, Olga G., Putilov, Arcady A.

“…Sub-constructs of morning-evening preference might be differentially related to polymorphisms in circadian clock genes. We previously reported significant…”
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Filaggrin mutations in a Western siberian population and their association with atopic dermatitis in children by Komova, Elena G, Shintyapina, Alexandra B, Makarova, Svetlana I, Ivanov, Mikhail K, Chekryga, Elena A, Kaznacheeva, Larisa F, Vavilin, Valentin A

“…We determined the frequencies of null mutations of the FLG gene--2282del4, R501X, R2447X, 3702delG, S3247X, and the 12-repeat allele (rs12730241)--among 460…”
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Synthesis of a new class of bisheterocycles via the Heck reaction of eudesmane type methylene lactones with 8-bromoxanthines by Patrushev, Sergey S., Rybalova, Tatyana V., Ivanov, Igor D., Vavilin, Valentin A., Shults, Elvira E.

“…The eudesmane-type methylene lactones (isoalantolactone, alantolactone, 4,15-epoxyisoalantolactone,…”
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The gene expression profile of a drug metabolism system and signal transduction pathways in the liver of mice treated with tert-butylhydroquinone or 3 by Shintyapina, Alexandra B, Vavilin, Valentin A, Safronova, Olga G, Lyakhovich, Vyacheslav V

“…Tert-butylhydroquinone (tBHQ) is a highly effective phenolic antioxidant used in edible oils and fats in foods as well as in medicines and cosmetics. TBHQ has…”
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Functional Analysis of the Unique Cytochrome P450 of the Liver Fluke Opisthorchis felineus: e0004258 by Pakharukova, Mariya Y, Vavilin, Valentin A, Sripa, Banchob, Laha, Thewarach, Brindley, Paul J, Mordvinov, Viatcheslav A

“…The basic metabolic cytochrome P450 (CYP) system is essential for biotransformation of sterols and xenobiotics including drugs, for synthesis and degradation…”
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The role of filaggrin mutations leading to a decrease in the amount of protein in the development of atopic dermatitis and bronchial asthma in children by Makarova, S. I., Mitrofanov, D. V., Komova, E. G., Kaloshkin, I. V., Shintyapina, A. B., Kaznacheeva, L. F., Zelenskaya, V. V., Kondyurina, Е. G., Batychko, О. A., Vavilin, V. A.

“…Atopic diseases remain one of the most common childhood diseases. At the beginning of life, atopic dermatitis (AD) occurs, and only then bronchial asthma (BA)…”
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