Search Results - "Vavalle, J. P."

A phase 1 ascending dose study of a subcutaneously administered factor IXa inhibitor and its active control agent by VAVALLE, J. P., RUSCONI, C. P., ZELENKOFSKE, S., WARGIN, W. A., ALEXANDER, J. H., BECKER, R. C.

“…Background:  The REG2 anticoagulation system consists of pegnivacogin, a subcutaneously administered aptamer factor IXa inhibitor, and its intravenous control…”
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Current Status of Percutaneous PFO Closure by Rohrhoff, N., Vavalle, J. P., Halim, S., Kiefer, T. L., Harrison, J. K.

“…The clinical significance of persistent patent foramen ovale (PFO) is not well defined. Empirically, PFO has been associated with many clinical conditions. In…”
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The effect of the REG2 Anticoagulation System on thrombin generation kinetics: a pharmacodynamic and pharmacokinetic first-in-human study by Vavalle, J. P., Rusconi, C. P., Zelenkofske, S., Wargin, W. A., Ortel, T. L., Alexander, J. H., Povsic, T. J., Becker, R. C.

“…The REG2 Anticoagulation System consists of pegnivacogin, a subcutaneously administered aptamer factor IXa inhibitor, and its intravenous active control agent,…”
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Plasma fibronectin levels and coronary artery disease by VAVALLE, J. P., WU, S. S., HUGHEY, R., MADAMANCHI, N. R., STOUFFER, G. A.

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SNIP, a Novel SNAP-25-interacting Protein Implicated in Regulated Exocytosis by Chin, Lih-Shen, Nugent, Russel D., Raynor, Mathew C., Vavalle, John P., Li, Lian

“…Synaptosome-associated protein of 25 kDa (SNAP-25) is a presynaptic membrane protein that has been clearly implicated in membrane fusion in both developing and…”
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Staring, a Novel E3 Ubiquitin-Protein Ligase That Targets Syntaxin 1 for Degradation by Chin, Lih-Shen, Vavalle, John P, Li, Lian

“…Syntaxin 1 is an essential component of the neurotransmitter release machinery, and regulation of syntaxin 1 expression levels is thought to contribute to the…”
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Sclerosing mesenteritis successfully treated with a TNF antagonist by Rothlein, Lisa R, Shaheen, Amy W, Vavalle, John P, Smith, Scott V, Renner, Jordan B, Shaheen, Nicholas J, Tarrant, Teresa K

“…A 29-year-old female presented with intermittent nausea, vomiting, fevers, abdominal pain and fatigue. CT scans of the abdomen revealed inflammatory changes…”
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