Search Results - "Vauterin, S"

ADAMTS‐13 plasma level determination uncovers antigen absence in acquired thrombotic thrombocytopenic purpura and ethnic differences by FEYS, H. B., LIU, F., DONG, N., PAREYN, I., VAUTERIN, S., VANDEPUTTE, N., NOPPE, W., RUAN, C., DECKMYN, H., VANHOORELBEKE, K.

“…Background: The recently discovered plasma enzyme ADAMTS‐13 cleaves the A2‐domain of von Willebrand factor (VWF). A defective cleaving protease results in…”
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The von Willebrand factor self‐association is modulated by a multiple domain interaction by ULRICHTS, H., VANHOORELBEKE, K., GIRMA, J. P., LENTING, P. J., VAUTERIN, S., DECKMYN, H.

“…Background: Platelet adhesion and aggregation at sites of vascular injury exposed to rapid blood flow require von Willebrand factor (VWF). VWF becomes…”
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ADAMTS‐13 plasma level determination uncovers antigen absence in acquired thrombotic thrombocytopenic purpura and ethnic differences by FEYS, H.B., LIU, F., DONG, N., PAREYN, I., VAUTERIN, S., VANDEPUTTE, N., NOPPE, W., RUAN, C., DECKMYN, H., VANHOORELBEKE, K.

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Identification of Peptides, Selected by Phage Display Technology, That Inhibit von Willebrand Factor Binding to Collagen by Depraetere, H., Viaene, A., Deroo, S., Vauterin, S., Deckmyn, H.

“…A repeated selection of phages from a cyclic hexapeptide phage display library resulted in an enrichment of phages that bound to the monoclonal antibody (MoAb)…”
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Structural determinants within platelet glycoprotein Ibα involved in its binding to von Willebrand factor by Cauwenberghs, K. Vanhoorelbeke, S. Vauterin, H. Deckmyn, N.

“…Platelet adhesion to subendothelial structures upon injury to a vessel wall is one of the first steps in a sequence of reactions critical for the formation of…”
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Sequence alignment between vWF and peptides inhibiting the vWF-collagen interaction does not result in the identification of a collagen-binding site in vWF by Vanhoorelbeke, K, van der Plas, R M, Vandecasteele, G, Vauterin, S, Huizinga, E G, Sixma, J J, Deckmyn, H

“…We previously found that two peptides (N- and Q-peptide) selected by phage display for binding to an anti-vWF antibody, were able to inhibit vWF-binding to…”
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Fc-receptor dependent platelet aggregation induced by monoclonal antibodies against platelet glycoprotein Ib or von Willebrand factor by Cauwenberghs, N, Schlammadinger, A, Vauterin, S, Cooper, S, Descheemaeker, G, Tornai, I, Deckmyn, H

“…In this paper we describe two pathways leading to platelet activation by crosslinking glycoprotein (GP) Ibalpha to the platelet Fc-receptor (FcgammaRII). First…”
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Occurrence of the Asn45Ser mutation in the GPIX gene in a Belgian patient with Bernard Soulier syndrome by Vanhoorelbeke, A. Schlammadinger, J.-P. Delville, J. Handsaeme, G. Vandecasteele, S. Vauterin, O. Pradier, W. Wijns, H. Deckmyn, K.

“…Bernard Soulier Syndrome (BSS) is a rare inherited bleeding disorder caused by a defect in the glycoprotein (GP)Ib/IX/V complex. A patient with a bleeding…”
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Identification of peptides, selected by phage display technology, that inhibit von Willebrand factor binding to collagen by DEPRAETERE, H, VIAENE, A, DEROO, S, VAUTERIN, S, DECKMYN, H

“…A repeated selection of phages from a cyclic hexapeptide phage display library resulted in an enrichment of phages that bound to the monoclonal antibody (MoAb)…”
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Characterization of murine anti-glycoprotein Ib monoclonal antibodies that differentiate between shear-induced and ristocetin/botrocetin-induced glycoprotein Ib-von Willebrand factor interaction by Cauwenberghs, N, Ajzenberg, N, Vauterin, S, Hoylaerts, M F, Declerck, P J, Baruch, D, Deckmyn, H

“…Platelet adhesion to vascular subendothelium under conditions of high shear stress is mediated by the platelet glycoprotein (GP) Ib-von Willebrand Factor (vWF)…”
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A reliable and reproducible ELISA method to measure ristocetin cofactor activity of von Willebrand factor by Vanhoorelbeke, K, Cauwenberghs, N, Vauterin, S, Schlammadinger, A, Mazurier, C, Deckmyn, H

“…The ristocetin induced binding of vWF to GPIb, which is routinely tested in a platelet agglutination assay, can be reproducibly studied in an ELISA where…”
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Von Willebrand Factor But Not α-Thrombin Binding to Platelet Glycoprotein Ibα Is Influenced by the HPA-2 Polymorphism by Ulrichts, Hans, Vanhoorelbeke, Karen, Cauwenberghs, Sandra, Vauterin, Stephan, Kroll, Hartmut, Santoso, Sentot, Deckmyn, Hans

“…OBJECTIVE—Glycoprotein (GP) Ibα is the functionally dominant subunit of the platelet GPIb-IX-V receptor complex. The N-terminal domain of the GPIbα chain…”
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THE DISTURBED MULTIMER PATTERN OF VWF R1374C IS NOT DUE TO INCREASED ADAMTS13 MEDIATED PROTEOLYSIS by Staelens, S., Pareyn, I., Feys, H.B., Vauterin, S., Wijns, W., Deckmyn, H., Vanhoorelbeke, K.

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Antithrombotic Effect of Platelet Glycoprotein Ib–Blocking Monoclonal Antibody Fab Fragments in Nonhuman Primates by Cauwenberghs, Nancy, Meiring, Muriel, Vauterin, Stephan, van Wyk, Veronika, Lamprecht, Seb, Roodt, Jan P, Novák, Levente, Harsfalvi, Jolan, Deckmyn, Hans, Kotzé, Harry F

“…Platelet adhesion in arterial blood flow is mainly supported by the platelet receptor glycoprotein (GP) Ib, which interacts with von Willebrand factor (vWF)…”
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Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibα reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibα by Cauwenberghs, Nancy, Vanhoorelbeke, Karen, Vauterin, Stephan, Westra, Douwe F., Romo, Gabriel, Huizinga, Eric G., Lopez, José A., Berndt, Michael C., Harsfalvi, Jolàn, Deckmyn, Hans

“…The interaction of von Willebrand factor (vWF) with the platelet receptor glycoprotein Ibα (GPIbα) is important for platelet adhesion at high shear stress. Two…”
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Paratope Determination of the Antithrombotic Antibody 82D6A3 Based on the Crystal Structure of Its Complex with the von Willebrand Factor A3-Domain by Staelens, Stephanie, Hadders, Michael A., Vauterin, Stephan, Platteau, Céline, De Maeyer, Marc, Vanhoorelbeke, Karen, Huizinga, Eric G., Deckmyn, Hans

“…The antithrombotic monoclonal antibody 82D6A3 is directed against amino acids Arg-963, Pro-981, Asp-1009, Arg-1016, Ser-1020, Met-1022, and His-1023 of the von…”
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How does agkicetin-C bind on platelet glycoprotein Ibα and achieve its platelet effects? by Xu, Gufeng, Ulrichts, Hans, Vauterin, Stephan, De Meyer, Simon F., Deckmyn, Hans, Teng, Maikun, Niu, Liwen

“…The platelet glycoprotein (GP) Ib-IX-V receptor complex has a central role in primary haemostasis and possesses binding sites for the plasmatic adhesive…”
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A Reliable von Willebrand factor: ristocetin cofactor enzyme-linked immunosorbent assay to differentiate between type 1 and type 2 von Willebrand disease by Vanhoorelbeke, Karen, Cauwenberghs, Nancy, Vandecasteele, Griet, Vauterin, Stephan, Deckmyn, Hans

“…von Willebrand disease (vWD) is the most common hereditary bleeding disorder due to either a qualitative or a quantitative defect in von Willebrand factor…”
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von Willebrand factor but not alpha-thrombin binding to platelet glycoprotein Ibalpha is influenced by the HPA-2 polymorphism by Ulrichts, Hans, Vanhoorelbeke, Karen, Cauwenberghs, Sandra, Vauterin, Stephan, Kroll, Hartmut, Santoso, Sentot, Deckmyn, Hans

“…Glycoprotein (GP) Ibalpha is the functionally dominant subunit of the platelet GPIb-IX-V receptor complex. The N-terminal domain of the GPIbalpha chain…”
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Structural determinants within platelet glycoprotein Ibalpha involved in its binding to von Willebrand factor by Cauwenberghs, N, Vanhoorelbeke, K, Vauterin, S, Deckmyn, H

“…Platelet adhesion to subendothelial structures upon injury to a vessel wall is one of the first steps in a sequence of reactions critical for the formation of…”
Get full text