Search Results - "Vaughn, David"

Development and evaluation of AS03, an Adjuvant System containing α-tocopherol and squalene in an oil-in-water emulsion by Garçon, Nathalie, Vaughn, David W, Didierlaurent, Arnaud M

“…AS03 is an Adjuvant System composed of α-tocopherol, squalene and polysorbate 80 in an oil-in-water emulsion. In various nonclinical and clinical studies, high…”
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Evaluation of post-introduction COVID-19 vaccine effectiveness: Summary of interim guidance of the World Health Organization by Patel, Minal K., Bergeri, Isabel, Bresee, Joseph S., Cowling, Benjamin J., Crowcroft, Natasha S., Fahmy, Kamal, Hirve, Siddhivinayak, Kang, Gagandeep, Katz, Mark A., Lanata, Claudio F., L'Azou Jackson, Maïna, Joshi, Sudhir, Lipsitch, Marc, Mwenda, Jason M., Nogareda, Francisco, Orenstein, Walter A., Ortiz, Justin R., Pebody, Richard, Schrag, Stephanie J., Smith, Peter G., Srikantiah, Padmini, Subissi, Lorenzo, Valenciano, Marta, Vaughn, David W., Verani, Jennifer R., Wilder-Smith, Annelies, Feikin, Daniel R.

“…Phase 3 randomized-controlled trials have provided promising results of COVID-19 vaccine efficacy, ranging from 50 to 95% against symptomatic disease as the…”
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Combined MTOR and autophagy inhibition: Phase I trial of hydroxychloroquine and temsirolimus in patients with advanced solid tumors and melanoma by Rangwala, Reshma, Chang, Yunyoung C, Hu, Janice, Algazy, Kenneth M, Evans, Tracey L, Fecher, Leslie A, Schuchter, Lynn M, Torigian, Drew A, Panosian, Jeffrey T, Troxel, Andrea B, Tan, Kay-See, Heitjan, Daniel F, DeMichele, Angela M, Vaughn, David J, Redlinger, Maryann, Alavi, Abass, Kaiser, Jonathon, Pontiggia, Laura, Davis, Lisa E, O'Dwyer, Peter J, Amaravadi, Ravi K

“…The combination of temsirolimus (TEM), an MTOR inhibitor, and hydroxychloroquine (HCQ), an autophagy inhibitor, augments cell death in preclinical models. This…”
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Primum non nocere: active surveillance for clinical stage I testicular cancer by Vaughn, David J

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Comprehensive Audiometric Analysis of Hearing Impairment and Tinnitus After Cisplatin-Based Chemotherapy in Survivors of Adult-Onset Cancer by Frisina, Robert D, Wheeler, Heather E, Fossa, Sophie D, Kerns, Sarah L, Fung, Chunkit, Sesso, Howard D, Monahan, Patrick O, Feldman, Darren R, Hamilton, Robert, Vaughn, David J, Beard, Clair J, Budnick, Amy, Johnson, Eileen M, Ardeshir-Rouhani-Fard, Shirin, Einhorn, Lawrence H, Lipshultz, Steven E, Dolan, M Eileen, Travis, Lois B

“…Cisplatin is widely used but highly ototoxic. Effects of cumulative cisplatin dose on hearing loss have not been comprehensively evaluated in survivors of…”
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Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma by Bellmunt, Joaquim, de Wit, Ronald, Vaughn, David J, Fradet, Yves, Lee, Jae-Lyun, Fong, Lawrence, Vogelzang, Nicholas J, Climent, Miguel A, Petrylak, Daniel P, Choueiri, Toni K, Necchi, Andrea, Gerritsen, Winald, Gurney, Howard, Quinn, David I, Culine, Stéphane, Sternberg, Cora N, Mai, Yabing, Poehlein, Christian H, Perini, Rodolfo F, Bajorin, Dean F

“…In a randomized trial involving 542 patients with relapsed urothelial cancer, treatment with pembrolizumab resulted in overall survival of more than 10 months,…”
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Pioglitazone Use and Risk of Bladder Cancer and Other Common Cancers in Persons With Diabetes by Lewis, James D, Habel, Laurel A, Quesenberry, Charles P, Strom, Brian L, Peng, Tiffany, Hedderson, Monique M, Ehrlich, Samantha F, Mamtani, Ronac, Bilker, Warren, Vaughn, David J, Nessel, Lisa, Van Den Eeden, Stephen K, Ferrara, Assiamira

“…IMPORTANCE: Studies suggest pioglitazone use may increase risk of cancers. OBJECTIVE: To examine whether pioglitazone use for diabetes is associated with risk…”
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Predicting Outcomes in Men With Metastatic Nonseminomatous Germ Cell Tumors (NSGCT): Results From the IGCCCG Update Consortium by Gillessen, Silke, Sauvé, Nicolas, Collette, Laurence, Daugaard, Gedske, de Wit, Ronald, Albany, Costantine, Tryakin, Alexey, Fizazi, Karim, Stahl, Olof, Gietema, Jourik A, De Giorgi, Ugo, Cafferty, Fay H, Hansen, Aaron R, Tandstad, Torgrim, Huddart, Robert A, Necchi, Andrea, Sweeney, Christopher J, Garcia-Del-Muro, Xavier, Heng, Daniel Y C, Lorch, Anja, Chovanec, Michal, Winquist, Eric, Grimison, Peter, Feldman, Darren R, Terbuch, Angelika, Hentrich, Marcus, Bokemeyer, Carsten, Negaard, Helene, Fankhauser, Christian, Shamash, Jonathan, Vaughn, David J, Sternberg, Cora N, Heidenreich, Axel, Beyer, Jörg

“…The classification of the International Germ Cell Cancer Collaborative Group (IGCCCG) plays a pivotal role in the management of metastatic germ cell tumors but…”
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Protein secondary-shell interactions enhance the photoinduced hydrogen production of cobalt protoporphyrin IX by Sommer, Dayn Joseph, Vaughn, Michael David, Ghirlanda, Giovanna

“…Hydrogen is an attractive fuel with potential for production scalability, provided that inexpensive, efficient molecular catalysts utilizing base metals can be…”
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Detection of post-vaccination enhanced dengue virus infection in macaques: An improved model for early assessment of dengue vaccines by Borges, Maria Beatriz, Marchevsky, Renato Sergio, Carvalho Pereira, Renata, da Silva Mendes, Ygara, Almeida Mendes, Luiz Gustavo, Diniz-Mendes, Leonardo, Cruz, Michael A, Tahmaoui, Ouafaâ, Baudart, Sébastien, Freire, Marcos, Homma, Akira, Schneider-Ohrum, Kirsten, Vaughn, David W, Vanloubbeeck, Yannick, Lorin, Clarisse, Malice, Marie-Pierre, Caride, Elena, Warter, Lucile

“…The need for improved dengue vaccines remains since the only licensed vaccine, Dengvaxia, shows variable efficacy depending on the infecting dengue virus…”
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Scientific rationale for developing potent RBD-based vaccines targeting COVID-19 by Kleanthous, Harry, Silverman, Judith Maxwell, Makar, Karen W., Yoon, In-Kyu, Jackson, Nicholas, Vaughn, David W.

“…Vaccination of the global population against COVID-19 is a great scientific, logistical, and moral challenge. Despite the rapid development and authorization…”
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Health-Related Quality-of-Life Analysis From KEYNOTE-045: A Phase III Study of Pembrolizumab Versus Chemotherapy for Previously Treated Advanced Urothelial Cancer by Vaughn, David J, Bellmunt, Joaquim, Fradet, Yves, Lee, Jae Lyun, Fong, Lawrence, Vogelzang, Nicholas J, Climent, Miguel A, Petrylak, Daniel P, Choueiri, Toni K, Necchi, Andrea, Gerritsen, Winald, Gurney, Howard, Quinn, David I, Culine, Stephane, Sternberg, Cora N, Mai, Yabing, Li, Haojie, Perini, Rodolfo F, Bajorin, Dean F, de Wit, Ronald

“…Purpose In the phase III KEYNOTE-045 study ( ClinicalTrials.gov identifier: NCT02256436), pembrolizumab significantly prolonged overall survival compared with…”
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Risk of Bladder Cancer Among Diabetic Patients Treated With Pioglitazone: Interim report of a longitudinal cohort study by Lewis, James D, Ferrara, Assiamira, Peng, Tiffany, Hedderson, Monique, Bilker, Warren B, Quesenberry, Charles P. Jr, Vaughn, David J, Nessel, Lisa, Selby, Joseph, Strom, Brian L

“…OBJECTIVE: Some preclinical in vivo studies and limited human data suggest a possible increased risk of bladder cancer with pioglitazone therapy. This is an…”
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Prognostic Factors in Patients With Advanced Transitional Cell Carcinoma of the Urothelial Tract Experiencing Treatment Failure With Platinum-Containing Regimens by BELLMUNT, Joaquim, CHOUEIRI, Toni K, FOUGERAY, Ronan, SCHUTZ, Fabio A. B, SALHI, Yacine, WINQUIST, Eric, CULINE, Stéphane, VON DER MAASE, Hans, VAUGHN, David J, ROSENBERG, Jonathan E

“…PURPOSE The present study sought to identify pretreatment prognostic factors for overall survival (OS) in patients with metastatic transitional cell carcinoma…”
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Lower abdominal and pelvic radiation and testicular germ cell tumor risk by Nead, Kevin T, Mitra, Nandita, Weathers, Benita, Pyle, Louisa, Emechebe, Nnadozie, Pucci, Donna A, Jacobs, Linda A, Vaughn, David J, Nathanson, Katherine L, Kanetsky, Peter A

“…Testicular germ cell tumor (TGCT) incidence has increased in recent decades along with the use and dose of diagnostic radiation. Here we examine the…”
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Survival and New Prognosticators in Metastatic Seminoma: Results From the IGCCCG-Update Consortium by Beyer, Jörg, Collette, Laurence, Sauvé, Nicolas, Daugaard, Gedske, Feldman, Darren R, Tandstad, Torgrim, Tryakin, Alexey, Stahl, Olof, Gonzalez-Billalabeitia, Enrique, De Giorgi, Ugo, Culine, Stéphane, de Wit, Ronald, Hansen, Aaron R, Bebek, Marko, Terbuch, Angelika, Albany, Costantine, Hentrich, Marcus, Gietema, Jourik A, Negaard, Helene, Huddart, Robert A, Lorch, Anja, Cafferty, Fay H, Heng, Daniel Y C, Sweeney, Christopher J, Winquist, Eric, Chovanec, Michal, Fankhauser, Christian, Stark, Daniel, Grimison, Peter, Necchi, Andrea, Tran, Ben, Heidenreich, Axel, Shamash, Jonathan, Sternberg, Cora N, Vaughn, David J, Duran, Ignacio, Bokemeyer, Carsten, Patrikidou, Anna, Cathomas, Richard, Assele, Samson, Gillessen, Silke

“…The classification of the International Germ-Cell Cancer Collaborative Group (IGCCCG) has been a major advance in the management of germ-cell tumors, but…”
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American Society of Clinical Oncology Clinical Evidence Review on the Ongoing Care of Adult Cancer Survivors: Cardiac and Pulmonary Late Effects by CARVER, Joseph R, SHAPIRO, Charles L, NG, Andrea, JACOBS, Linda, SCHWARTZ, Cindy, VIRGO, Katherine S, HAGERTY, Karen L, SOMERFIELD, Mark R, VAUGHN, David J

“…To review the evidence on the incidence of long-term cardiac or pulmonary toxicity secondary to chemotherapy, radiotherapy, or trastuzumab in symptomatic and…”
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Efficacy of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Inhibitor, in Patients with Previously Treated Advanced Urothelial Carcinoma with FGFR3 Alterations by Pal, Sumanta K, Rosenberg, Jonathan E, Hoffman-Censits, Jean H, Berger, Raanan, Quinn, David I, Galsky, Matthew D, Wolf, Juergen, Dittrich, Christian, Keam, Bhumsuk, Delord, Jean-Pierre, Schellens, Jan H M, Gravis, Gwenaelle, Medioni, Jacques, Maroto, Pablo, Sriuranpong, Virote, Charoentum, Chaiyut, Burris, Howard A, Grünwald, Viktor, Petrylak, Daniel, Vaishampayan, Ulka, Gez, Eliahu, De Giorgi, Ugo, Lee, Jae-Lyun, Voortman, Jens, Gupta, Sumati, Sharma, Sunil, Mortazavi, Amir, Vaughn, David J, Isaacs, Randi, Parker, Katie, Chen, Xueying, Yu, Kun, Porter, Dale, Graus Porta, Diana, Bajorin, Dean F

“…BGJ398, a potent and selective pan-FGFR antagonist, was prospectively evaluated in patients with metastatic urothelial carcinoma bearing a diverse array of…”
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Insufficient Clarity of Statement 6 in the Consensus Opinions to Prevent Neurologic Complications after Epidural Steroid Injections by Vaughn, David R

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Reply to J. Beyer, T. Tandstad et al, S. Gillessen et al, J. Oldenburg et al, and L.C. Pagliaro et al by Vaughn, David J

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