Search Results - "Vaughan, Sydney K."

Degeneration of proprioceptive sensory nerve endings in mice harboring amyotrophic lateral sclerosis-causing mutations by Vaughan, Sydney K., Kemp, Zachary, Hatzipetros, Theo, Vieira, Fernando, Valdez, Gregorio

“…ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that primarily targets the motor system. Although much is known about the effects…”
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Specific labeling of synaptic schwann cells reveals unique cellular and molecular features by Castro, Ryan, Taetzsch, Thomas, Vaughan, Sydney K, Godbe, Kerilyn, Chappell, John, Settlage, Robert E, Valdez, Gregorio

“…Perisynaptic Schwann cells (PSCs) are specialized, non-myelinating, synaptic glia of the neuromuscular junction (NMJ), that participate in synapse development,…”
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The ALS-inducing factors, TDP43A315T and SOD1G93A, directly affect and sensitize sensory neurons to stress by Vaughan, Sydney K., Sutherland, Natalia M., Zhang, Sihui, Hatzipetros, Theo, Vieira, Fernando, Valdez, Gregorio

“…There is increased recognition that sensory neurons located in dorsal root ganglia (DRG) are affected in amyotrophic lateral sclerosis (ALS). However, it…”
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Attenuating Cholinergic Transmission Increases the Number of Satellite Cells and Preserves Muscle Mass in Old Age by Vaughan, Sydney K, Sutherland, Natalia M, Valdez, Gregorio

“…In addition to driving contraction of skeletal muscles, acetylcholine (ACh) acts as an anti-synaptogenic agent at neuromuscular junctions (NMJs). Previous…”
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Impact of Aging on Proprioceptive Sensory Neurons and Intrafusal Muscle Fibers in Mice by Vaughan, Sydney K, Stanley, Olivia L, Valdez, Gregorio

“…The impact of aging on proprioceptive sensory neurons and intrafusal muscle fibers (IMFs) remains largely unexplored despite the central function these cells…”
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Degeneration of proprioceptive sensory nerve endings in mice harboring amyotrophic lateral sclerosis-causing mutations by Vaughan, Sydney K., Kemp, Zachary, Hatzipetros, Theo, Vieira, Fernando, Valdez, Gregorio

“…ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that primarily targets the motor system. Although much is known about the effects…”
Get full text

VAChT overexpression increases acetylcholine at the synaptic cleft and accelerates aging of neuromuscular junctions by Sugita, Satoshi, Fleming, Leland L, Wood, Caleb, Vaughan, Sydney K, Gomes, Matheus P S M, Camargo, Wallace, Naves, Ligia A, Prado, Vania F, Prado, Marco A M, Guatimosim, Cristina, Valdez, Gregorio

“…Cholinergic dysfunction occurs during aging and in a variety of diseases, including amyotrophic lateral sclerosis (ALS). However, it remains unknown whether…”
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Fast and slow-twitching muscles are differentially affected by reduced cholinergic transmission in mice deficient for VAChT: A mouse model for congenital myasthenia by Magalhães-Gomes, Matheus P.S., Motta-Santos, Daisy, Schetino, Luana P.L., Andrade, Jéssica N., Bastos, Cristiane P., Guimarães, Diogo A.S., Vaughan, Sydney K., Martinelli, Patrícia M., Guatimosim, Silvia, Pereira, Grace S., Coimbra, Candido C., Prado, Vânia F., Prado, Marco A.M., Valdez, Gregorio, Guatimosim, Cristina

“…Congenital myasthenic syndromes (CMS) result from reduced cholinergic transmission at neuromuscular junctions (NMJs). While the etiology of CMS varies, the…”
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The ALS-inducing factors, TDP43 A315T and SOD1 G93A , directly affect and sensitize sensory neurons to stress by Vaughan, Sydney K, Sutherland, Natalia M, Zhang, Sihui, Hatzipetros, Theo, Vieira, Fernando, Valdez, Gregorio

“…There is increased recognition that sensory neurons located in dorsal root ganglia (DRG) are affected in amyotrophic lateral sclerosis (ALS). However, it…”
Get full text