Search Results - "Vaughan, K."
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Degeneration of proprioceptive sensory nerve endings in mice harboring amyotrophic lateral sclerosis-causing mutations
Published in Journal of comparative neurology (1911) (01-12-2015)“…ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that primarily targets the motor system. Although much is known about the effects…”
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Evaluating the Single Service Point Using the Person-Environment-Occupation Model
Published in Portal (Baltimore, Md.) (01-04-2020)“…An academic library's single service point, where users can get answers and help with their library needs in one place, is often the first and most popular…”
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Use of a capillary specimen in the laboratory to verify a point‐of‐care international normalized ratio: Avoidance of a venipuncture in a pediatric setting
Published in International journal of laboratory hematology (01-02-2019)“…Introduction Point‐of‐care (POC) international normalized ratio (INR) values above an institutional cutoff are confirmed in the laboratory using a gold…”
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A simple kaolin clotting time confirm ratio for the presence of a lupus anticoagulant
Published in Pathology (01-06-2018)Get full text
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Specific labeling of synaptic schwann cells reveals unique cellular and molecular features
Published in eLife (25-06-2020)“…Perisynaptic Schwann cells (PSCs) are specialized, non-myelinating, synaptic glia of the neuromuscular junction (NMJ), that participate in synapse development,…”
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Threonine 22 Phosphorylation Attenuates Hsp90 Interaction with Cochaperones and Affects Its Chaperone Activity
Published in Molecular cell (18-03-2011)“…Heat shock protein 90 (Hsp90) is an essential molecular chaperone whose activity is regulated not only by cochaperones but also by distinct posttranslational…”
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Hsp90 Picks PIKKs via R2TP and Tel2
Published in Structure (London) (10-06-2014)“…Phosphatidylinositol-3 kinase-like kinases (PIKKs) are dependent on Hsp90 for their activation via the R2TP complex and Tel2. In this issue of Structure, Pal…”
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The ALS-inducing factors, TDP43A315T and SOD1G93A, directly affect and sensitize sensory neurons to stress
Published in Scientific reports (08-11-2018)“…There is increased recognition that sensory neurons located in dorsal root ganglia (DRG) are affected in amyotrophic lateral sclerosis (ALS). However, it…”
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Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10
Published in Cell reports (Cambridge) (17-07-2018)“…The centromere binding factor 3 (CBF3) complex binds the third centromere DNA element in organisms with point centromeres, such as S. cerevisiae. It is an…”
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Food addiction in children: Associations with obesity, parental food addiction and feeding practices
Published in Eating behaviors : an international journal (01-08-2017)“…Food addiction research in children is limited, and to date addictive-like eating behaviors within families have not been investigated. The aim of this study…”
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Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer
Published in Cell reports (Cambridge) (14-11-2017)“…The serine/threonine protein phosphatase 5 (PP5) regulates multiple cellular signaling networks. A number of cellular factors, including heat shock protein 90…”
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Hsp90-Dependent Activation of Protein Kinases Is Regulated by Chaperone-Targeted Dephosphorylation of Cdc37
Published in Molecular cell (26-09-2008)“…Activation of protein kinase clients by the Hsp90 system is mediated by the cochaperone protein Cdc37. Cdc37 requires phosphorylation at Ser13, but little is…”
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The Incremental Association of Implementation Leadership and School Personnel Burnout Beyond Transformational Leadership
Published in School psychology (01-05-2024)“…Successful implementation of school-wide interventions (i.e., delivered to all students by a wide array of school personnel) is key to promoting students'…”
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Attenuating Cholinergic Transmission Increases the Number of Satellite Cells and Preserves Muscle Mass in Old Age
Published in Frontiers in aging neuroscience (24-09-2019)“…In addition to driving contraction of skeletal muscles, acetylcholine (ACh) acts as an anti-synaptogenic agent at neuromuscular junctions (NMJs). Previous…”
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Helping Educational Leaders Mobilize Evidence (HELM): The iterative redesign of the Leadership and Organizational Change for Implementation (LOCI) intervention for use in schools
Published in Implementation research and practice (01-01-2024)“…Few "intervention agnostic" strategies have been developed that can be applied to the broad array of evidence-based practices (EBPs) in schools. This paper…”
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Maternal vaccination as a Salmonella Typhimurium reduction strategy on pig farms
Published in Journal of applied microbiology (01-01-2018)“…Aims The control of Salmonella in pig production is necessary for public and animal health, and vaccination was evaluated as a strategy to decrease pig…”
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Parents' perception of quality of life in their sons with haemophilia
Published in Journal of paediatrics and child health (01-12-2016)“…Aim Quality of life (QOL) in haemophilia involves both physical and psychological issues. This study was performed to determine parents’ perceptions of the QOL…”
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Centering School Leaders’ Expertise: Usability Evaluation of a Leadership-Focused Implementation Strategy to Support Tier 1 Programs in Schools
Published in School mental health (01-09-2024)“…Although there are a growing number of implementation strategies to increase the adoption, fidelity, and sustainment of evidence-based practices (EBP), they…”
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Connecting the Libraries and Athletics through Instruction and Outreach
Published in Medical reference services quarterly (03-04-2017)“…This column describes the approaches taken by librarians and staff at James Madison University (JMU) Libraries & Educational Technologies (LET) to extend…”
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Crystal structure of an Hsp90–nucleotide–p23/Sba1 closed chaperone complex
Published in Nature (20-04-2006)“…Hsp90 (heat shock protein of 90 kDa) is a ubiquitous molecular chaperone responsible for the assembly and regulation of many eukaryotic signalling systems and…”
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