Search Results - "Vaughan, J H"

Effect of Neuropeptides on Production of Inflammatory Cytokines by Human Monocytes by Lotz, Martin, Vaughan, John H., Carson, Dennis A.

“…Two groups of mediators, the neuropeptides substance P and K and the monocytederived cytokines, interact in the neural regulation of immunological and…”
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The Epstein-Barr virus and systemic lupus erythematosus by Vaughan, J H

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Detection of Epstein-Barr virus-associated antigens and DNA in salivary gland biopsies from patients with Sjogren's syndrome by Fox, RI, Pearson, G, Vaughan, JH

“…Sjogren's syndrome (SS) is an autoimmune disorder characterized by lymphocytic infiltration of salivary and lacrimal glands. To determine whether Epstein-Barr…”
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Synovium as a source of interleukin 6 in vitro: contribution to local and systemic manifestations of arthritis by GUERNE, P.-A, ZURAW, B. L, VAUGHAN, J. H, CARSON, D. A, LOTZ, M

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Evidence of activation of 2 herpesviruses, Epstein-Barr virus and cytomegalovirus, in systemic sclerosis and normal skins by Vaughan, J H, Shaw, P X, Nguyen, M D, Medsger, Jr, T A, Wright, T M, Metcalf, J S, Leroy, E C

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Substance P Activation of Rheumatoid Synoviocytes: Neural Pathway in Pathogenesis of Arthritis by Lotz, Martin, Carson, Dennis A., Vaughan, John H.

“…Several clinical features are consistent with nervous system involvement in the pathogenesis of rheumatoid arthritis. The neuropeptide substance P is one…”
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Viruses and autoimmune disease by Vaughan, J H

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Autoantibodies to human heat shock protein (hsp)60 may be induced by Escherichia coli groEL by HANDLEY, H. H., YU, J., YU, D. T. Y., SINGH, B., GUPTA, R. S., VAUGHAN, J. H.

“…SUMMARY The 65‐kD hsp from Mycobacterium tuberculosis has been reported to induce an autopathogenic subset of T cells in at least two animal models of…”
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The Epstein-Barr virus glycoprotein gp110, a molecular link between HLA DR4, HLA DR1, and rheumatoid arthritis by Roudier, J, Rhodes, G, Petersen, J, Vaughan, J H, Carson, D A

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Genetic influence on the levels of circulating CD5 B lymphocytes by Kipps, TJ, Vaughan, JH

“…By using sensitive two- and three-color immunofluorescence analyses, we readily detect CD5B cells (Leu 1 B cells) in the peripheral blood of normal adults…”
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Activation of resting T lymphocytes by anti-CD3 (T3) antibodies in the absence of monocytes by Tsoukas, CD, Landgraf, B, Bentin, J, Valentine, M, Lotz, M, Vaughan, JH, Carson, DA

“…The antigen receptor molecules on human T lymphocytes are noncovalently associated on the cell surface with the CD3 (T3) molecular complex. Perturbation of…”
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Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies by LOTZ, M, TSOUKAS, C. D, ROBINSON, C. A, DINARELLO, C. A, CARSON, D. A, VAUGHAN, J. H

“…Synovial fluid mononuclear cells (SFMC) from patients with active rheumatoid arthritis characteristically respond poorly to mitogens. In this study, mitogenic…”
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Autoantibodies in infectious mononucleosis have specificity for the glycine-alanine repeating region of the Epstein-Barr virus nuclear antigen by RHODES, G, RUMPOLD, H, KURKI, P, PATRICK, K. M, CARSON, D. A, VAUGHAN, J. H

“…Viruses have been postulated to be involved in the induction of autoantibodies by: autoimmunization with tissue proteins released by virally induced tissue…”
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The p542 Gene Encodes an Autoantigen that Cross-Reacts with EBNA-1 of the Epstein Barr Virus and which may be a Heterogeneous Nuclear Ribonucleoprotein by Rhodes, Gary H., Valbracht, Jean R., Nguyen, Minh-Duc, Vaughan, John H.

“…In infectious mononucleosis (IM), anti-EBNA-1 antibodies are produced which cross-react with multiple normal human proteins. The cross-reactions can be…”
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Human immune responses to synthetic peptides from the Epstein-Barr nuclear antigen by RHODES, G, CARSON, D. A, VALBRACHT, J, HOUGHTEN, R, VAUGHAN, J. H

“…Humans infected with Epstein-Barr virus (EBV), the causative agent of infectious mononucleosis, develop antibodies against a nuclear antigen (EBNA) that is…”
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The glycine-alanine repeating region is the major epitope of the Epstein-Barr nuclear antigen-1 (EBNA-1) by Rumpold, H, Rhodes, GH, Bloch, PL, Carson, DA, Vaughan, JH

“…The Epstein-Barr nuclear antigen-1 (EBNA-1) is a protein containing a large glycine-alanine repeat that has been shown to be antigenic. Antibodies to EBNA-1…”
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Antibodies to synthetic peptides from Epstein-Barr nuclear antigen-1 in sera of patients with early rheumatoid arthritis and in preillness sera by Kouri, T, Petersen, J, Rhodes, G, Aho, K, Palosuo, T, Heliövaara, M, Isomäki, H, von Essen, R, Vaughan, J H

“…We studied IgG antibody levels to synthetic peptides (p62, E11 and E3) from Epstein-Barr nuclear antigen-1 (EBNA-1) protein sequence in sera of patients with…”
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The majority of human monoclonal IgM rheumatoid factors express a "primary structure-dependent" cross-reactive idiotype by Chen, PP, Goni, F, Fong, S, Jirik, F, Vaughan, JH, Frangione, B, Carson, DA

“…Genetic studies of human immunoglobulin variable regions have been hampered by the lack of anti-idiotypic antibodies that recognize specific heavy and light…”
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Synovial fluid lymphocytes differ from peripheral blood lymphocytes in patients with rheumatoid arthritis by Fox, RI, Fong, S, Sabharwal, N, Carstens, SA, Kung, PC, Vaughan, JH

“…Peripheral blood (PBL) and synovial fluid lymphocytes (SFL) from 12 patients with rheumatoid arthritis (RA) were analyzed using monoclonal antibodies that…”
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Release of lymphokines after Epstein Barr virus infection in vitro. I. Sources of and kinetics of production of interferons and interleukins in normal humans by Lotz, M, Tsoukas, CD, Fong, S, Dinarello, CA, Carson, DA, Vaughan, JH

“…Infection of human lymphocytes with Epstein Barr virus (EBV) activates the release of lymphokines. Previous experiments have emphasized the ability of…”
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