Search Results - "Vaucheret, Herve"
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Plant ARGONAUTES
Published in Trends in plant science (01-07-2008)“…ARGONAUTE (AGO) proteins are integral players in all known small RNA-directed regulatory pathways. Eukaryotes produce numerous types of small RNAs, such as…”
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Epigenetic management of self and non-self: lessons from 40 years of transgenic plants
Published in Comptes rendus. Biologies (16-02-2023)“…Plant varieties exhibiting unstable or variegated phenotypes, or showing virus recovery have long remained a mystery. It is only with the development of…”
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The plant siRNA landscape
Published in The Plant cell (30-01-2024)“…Abstract Whereas micro (mi)RNAs are considered the clean, noble side of the small RNA world, small interfering (si)RNAs are often seen as a noisy set of…”
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Respective contributions of Arabidopsis DCL2 and DCL4 to RNA silencing
Published in The Plant journal : for cell and molecular biology (01-01-2015)“…Dicer proteins are central to the different mechanisms involving RNA interference. Plants have evolved multiple DICER‐LIKE (DCL) copies, thus enabling…”
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An antagonistic function for Arabidopsis DCL2 in development and a new function for DCL4 in generating viral siRNAs
Published in The EMBO journal (26-07-2006)“…Plants contain more DICER‐LIKE (DCL) enzymes and double‐stranded RNA binding (DRB) proteins than other eukaryotes, resulting in increased small RNA network…”
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The viral F-box protein P0 induces an ER-derived autophagy degradation pathway for the clearance of membrane-bound AGO1
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2019)“…RNA silencing is a major antiviral defense mechanism in plants and invertebrates. Plant ARGONAUTE1 (AGO1) is pivotal in RNA silencing, and hence is a major…”
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AGO1 Homeostasis Entails Coexpression of MIR168 and AGO1 and Preferential Stabilization of miR168 by AGO1
Published in Molecular cell (07-04-2006)“…Arabidopsis ARGONAUTE1 ( AGO1) encodes the RNA slicer enzyme of the microRNA (miRNA) pathway and is regulated by miR168-programmed, AGO1-catalyzed mRNA…”
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Nuclear processing and export of microRNAs in Arabidopsis
Published in Proceedings of the National Academy of Sciences - PNAS (08-03-2005)“…In mammalian cells, the nuclear export receptor, Exportin 5 (Exp5), exports pre-microRNAs (pre-miRNAs) as well as tRNAs into the cytoplasm. In this study, we…”
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Arabidopsis FIERY1, XRN2, and XRN3 Are Endogenous RNA Silencing Suppressors
Published in The Plant cell (01-11-2007)“…The eukaryotic defense response posttranscriptional gene silencing (PTGS) is directed by short-interfering RNAs and thwarts invading nucleic acids via the RNA…”
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Plants Encode a General siRNA Suppressor That Is Induced and Suppressed by Viruses
Published in PLoS biology (01-12-2015)“…Small RNAs play essential regulatory roles in genome stability, development, and responses to biotic and abiotic stresses in most eukaryotes. In plants, the…”
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Cytoplasmic and nuclear quality control and turnover of single-stranded RNA modulate post-transcriptional gene silencing in plants
Published in Nucleic acids research (01-04-2013)“…Eukaryotic RNA quality control (RQC) uses both endonucleolytic and exonucleolytic degradation to eliminate dysfunctional RNAs. In addition, endogenous and…”
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RNA Silencing in Plants-Defense and Counterdefense
Published in Science (American Association for the Advancement of Science) (22-06-2001)“…RNA silencing is a remarkable type of gene regulation based on sequence-specific targeting and degradation of RNA. The term encompasses related pathways found…”
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Synergistic action of the Arabidopsis spliceosome components PRP39a and SmD1b in promoting posttranscriptional transgene silencing
Published in The Plant cell (29-05-2023)“…Abstract Besides regulating splicing, the conserved spliceosome component SmD1 (Small nuclear ribonucleoprotein D1)b promotes posttranscriptional silencing of…”
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Ingested plant miRNAs regulate gene expression in animals
Published in Cell research (01-01-2012)“…The incidence of genetic material or epigenetic information transferred from one organism to another is an important biological question. A recent study…”
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Biotechnological uses of RNAi in plants: risk assessment considerations
Published in Trends in biotechnology (Regular ed.) (01-03-2015)“…RNAi offers opportunities to generate new traits in genetically modified (GM) plants. Instead of expressing novel proteins, RNAi-based GM plants reduce target…”
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Cytoplasmic Arabidopsis AGO7 accumulates in membrane-associated siRNA bodies and is required for ta-siRNA biogenesis
Published in The EMBO journal (04-04-2012)“…Formation of trans‐acting small interfering RNAs (ta‐siRNAs) from the TAS3 precursor is triggered by the AGO7/miR390 complex, which primes TAS3 for conversion…”
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Gene silencing in plants: A diversity of pathways
Published in Biochimica et biophysica acta (01-12-2013)“…Eukaryotic organisms have evolved a variety of gene silencing pathways in which small RNAs, 20- to 30-nucleotides in length, repress the expression of sequence…”
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RST1 and RIPR connect the cytosolic RNA exosome to the Ski complex in Arabidopsis
Published in Nature communications (27-08-2019)“…The RNA exosome is a key 3’−5’ exoribonuclease with an evolutionarily conserved structure and function. Its cytosolic functions require the co-factors SKI7 and…”
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Arabidopsis RNASE THREE LIKE2 Modulates the Expression of Protein-Coding Genes via 24-Nucleotide Small Interfering RNA-Directed DNA Methylation
Published in The Plant cell (01-02-2016)“…RNaseIII enzymes catalyze the cleavage of double-stranded RNA (dsRNA) and have diverse functions in RNA maturation. Arabidopsis thaliana RNASE THREE LIKE2…”
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Post-transcriptional gene silencing triggered by sense transgenes involves uncapped antisense RNA and differs from silencing intentionally triggered by antisense transgenes
Published in Nucleic acids research (30-09-2015)“…Although post-transcriptional gene silencing (PTGS) has been studied for more than a decade, there is still a gap in our understanding of how de novo silencing…”
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