Search Results - "Vataru Nakamura, Celso"
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Quinoxalines against Leishmania amazonensis: SAR study, proposition of a new derivative, QSAR prediction, synthesis, and biological evaluation
Published in Scientific reports (24-10-2023)“…Neglected tropical diseases, such as leishmaniasis, lead to serious limitations to the affected societies. In this work, a structure–activity relationship…”
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The Combination of Vitamin K3 and Vitamin C Has Synergic Activity against Forms of Trypanosoma cruzi through a Redox Imbalance Process
Published in PloS one (07-12-2015)“…Chagas' disease is an infection that is caused by the protozoan Trypanosoma cruzi, affecting millions of people worldwide. Because of severe side effects and…”
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Antileishmanial activity of diterpene acids in copaiba oil
Published in Memórias do Instituto Oswaldo Cruz (01-02-2013)“…Leishmaniasis is a neglected tropical disease. According to the World Health Organization, there are approximately 1.5-two million new cases of cutaneous…”
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Antileishmanial Activity of Parthenolide, a Sesquiterpene Lactone Isolated from Tanacetum parthenium
Published in Antimicrobial Agents and Chemotherapy (01-01-2005)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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In Vitro and In Vivo Trypanocidal Synergistic Activity of N-Butyl-1-(4-Dimethylamino)Phenyl-1,2,3,4-Tetrahydro-β-Carboline-3-Carboxamide Associated with Benznidazole
Published in Antimicrobial Agents and Chemotherapy (2012)“…American trypanosomiasis, or Chagas' disease, is caused by Trypanosoma cruzi and affects around 15 million people throughout the American continent. The…”
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Evaluation of antileishmanial activity of eupomatenoid-5, a compound isolated from leaves of Piper regnellii var. pallescens
Published in Parasitology international (01-06-2010)“…Abstract Infection with Leishmania spp. causes a disease with multifaceted clinical manifestations in humans. The treatment for leishmaniasis is dependent on a…”
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Activity of Neolignans Isolated from Piper regnellii (MIQ.) C. DC. var. pallescens (C. DC.) YUNCK against Trypanosoma cruzi
Published in Biological & Pharmaceutical Bulletin (2006)“…The in vitro antiproliferative effects of 4 neolignans purified from the ethyl-acetate extract from leaves of Piper regnellii (MIQ.) C. DC. var. pallescens (C…”
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Antileishmanial activity of Eugenol-rich essential oil from Ocimum gratissimum
Published in Parasitology international (01-06-2006)“…Leishmaniasis is a group of diseases with a large spectrum of clinical manifestations caused by protozoans of the genus Leishmania. Here we demonstrate the…”
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Comparison of the bacteriological quality of tap water and bottled mineral water
Published in International journal of hygiene and environmental health (01-10-2008)“…The bacteriological quality of tap water from municipal water supplies, 20-L bottles of mineral water from water dispensers and samples collected from new 20-L…”
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Additional evidence of the trypanocidal action of (-)-elatol on amastigote forms through the involvement of reactive oxygen species
Published in Marine drugs (25-09-2014)“…Chagas' disease, a vector-transmitted infectious disease, is caused by the protozoa parasite Trypanosoma cruzi. Drugs that are currently available for the…”
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Synthesis, Antitumor, Antitrypanosomal and Antileishmanial Activities of Benzo[4,5]canthin-6-ones Bearing the N′-(Substituted benzylidene)-carbohydrazide and N-Alkylcarboxamide Groups at C-2
Published in Chemical & pharmaceutical bulletin (01-11-2012)“…A series of novel benzo[4,5]canthin-6-ones, bearing the N′-(substituted benzylidene)-carbohydrazide (11a-e) and N-alkylcarboxamide (13a-g) moieties at…”
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Antileishmanial activity of a guaianolide from Tanacetum parthenium (L.) Schultz Bip
Published in Parasitology international (01-12-2010)“…Abstract Leishmaniasis is one of the major infectious diseases affecting the poorest regions of the world. The present study evaluated the antileishmanial…”
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Potent antifungal activity of extracts and pure compound isolated from pomegranate peels and synergism with fluconazole against Candida albicans
Published in Research in microbiology (01-09-2010)“…Activity-guided repeated fractionation of crude hydro alcoholic extract prepared from the fruit peel of Punica granatum on a silica-gel column yielded a…”
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Analysis of the antitumor activity of bioactive compounds of Cannabis flowers extracted by green solvents
Published in The Journal of supercritical fluids (01-07-2019)“…[Display omitted] •Supercritical extraction of cannabinoids in a simple and sequential step.•Research strategies to increase the content of Δ9-THC and CBD…”
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Ionized alkaline water reduces injury in BALB/c mice infected with Leishmania amazonensis
Published in PloS one (06-07-2023)“…Ionized water has been reported to contribute to the tissue repair process and wound healing. Water purifiers can generate ionized water by means of activated…”
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Inclusion Complexes of Litsea cubeba (Lour.) Pers Essential Oil into β-Cyclodextrin: Preparation, Physicochemical Characterization, Cytotoxicity and Antifungal Activity
Published in Molecules (Basel, Switzerland) (04-04-2024)“…The uses of natural compounds, such as essential oils (EOs), are limited due to their instability to light, oxygen and temperature, factors that affect their…”
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Natural products and Chagas' disease: a review of plant compounds studied for activity against Trypanosoma cruzi
Published in Natural product reports (01-01-2011)“…Here, we review studies that have investigated the activity of plant-derived compounds against Trypanosoma cruzi, the etiologic agent of Chagas’ disease. In…”
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Photophysical characterization of Hypericin-loaded in micellar, liposomal and copolymer-lipid nanostructures based F127 and DPPC liposomes
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-03-2021)“…[Display omitted] •Hy-formulations transient was studied.•Cytotoxicity showed potential for Copolymer-Lipid/Hy.•Copolymer-Lipid/Hy proved to be superior in…”
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β-Carboline-α-aminophosphonate Derivative: A Promising Antitumor Agent for Breast Cancer Treatment
Published in Molecules (Basel, Switzerland) (08-05-2023)“…Breast cancer is the most common type of cancer and the leading cause of cancer mortality among women worldwide. Considering the limitations of the current…”
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An evaluation of antibacterial activities of Psidium guajava (L.)
Published in Brazilian archives of biology and technology (01-05-2005)“…The present study was designated to evaluate the antibacterial activities of aqueous and ethanol:water extracts from leaves, roots and stem bark of Psidium…”
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