Search Results - "Vasyunina, Elena A."
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Age-dependent guanine oxidation in DNA of different brain regions of Wistar rats and prematurely aging OXYS rats
Published in Biochimica et biophysica acta (01-06-2013)“…Oxidative damage to the cell, including the formation of 8-oxoG, has been regarded as a significant factor in carcinogenesis and aging. An inbred prematurely…”
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Immunofluorescent detection of 8-oxoguanine DNA lesions in liver cells from aging OXYS rats, a strain prone to overproduction of free radicals
Published in Mutation research (25-07-2006)“…Production of free radicals in animals is accompanied with a number of pathologic conditions, some of which may be manifested through DNA damage. Studies of…”
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o-Aminoazotoluene does induce the enzymes of its own mutagenic activation in mouse liver
Published in Toxicology (Amsterdam) (01-07-2005)“…The objective of this study was to investigate the CYP1A1 and CYP1A2 mRNAs and enzyme activities in mouse liver during induction with o-aminoazotoluene (OAT)…”
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High frequency of somatic mutations in rat liver mitochondrial DNA
Published in Mutation research (01-03-2010)“…Somatic mutations in mitochondrial DNA (mtDNA) are thought to play an important role in both aging and neurodegenerative diseases although their specific…”
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Age-dependent increase of 8-oxoguanine-, hypoxanthine-, and uracil- DNA glycosylase activities in liver extracts from OXYS rats with inherited overgeneration of free radicals and Wistar rats
Published in Medical science monitor (01-01-2003)“…Oxygen free radicals have been hypothesized to play an important role in the process of aging. To investigate the correlation between oxidative stress and…”
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o-Aminoazotoluene does induce the enzymes of its own mutagenic activation in mouse liver
Published in Toxicology (Amsterdam) (2005)Get full text
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7
The molecular basis of the origin of complete and mosaic mutants
Published in Mutation research (01-01-1986)“…To study the molecular basis of the origin of complete and mosaic mutants, pBR322 plasmids with damage to one or both DNA strands were constructed by limited…”
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