Search Results - "Vasudevan, Aparna"

Alternatively activated macrophages; a double-edged sword in allergic asthma by Abdelaziz, Mohamed Hamed, Abdelwahab, Sayed F, Wan, Jie, Cai, Wei, Huixuan, Wang, Jianjun, Cheng, Kumar, Kesavan Dinesh, Vasudevan, Aparna, Sadek, Ahmed, Su, Zhaoliang, Wang, Shengjun, Xu, Huaxi

“…Macrophages are heterogenous phagocytic cells with an important role in the innate immunity. They are, also, significant contributors in the adaptive immune…”
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Identification of natural compound inhibitors for multidrug efflux pumps of Escherichia coli and Pseudomonas aeruginosa using in silico high-throughput virtual screening and in vitro validation by Aparna, Vasudevan, Dineshkumar, Kesavan, Mohanalakshmi, Narasumani, Velmurugan, Devadasan, Hopper, Waheeta

“…Pseudomonas aeruginosa and Escherichia coli are resistant to wide range of antibiotics rendering the treatment of infections very difficult. A main mechanism…”
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Integrative analysis of outer membrane vesicles proteomics and whole-cell transcriptome analysis of eravacycline induced Acinetobacter baumannii strains by Kesavan, DineshKumar, Vasudevan, Aparna, Wu, Liang, Chen, Jianguo, Su, Zhaoliang, Wang, Shengjun, Xu, Huaxi

“…Acinetobacter baumannii is a multidrug-resistant (MDR) hazardous bacterium with very high antimicrobial resistance profiles. Outer membrane vesicles (OMVs)…”
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Bacterial bug-out bags: outer membrane vesicles and their proteins and functions by Dineshkumar, Kesavan, Aparna, Vasudevan, Wu, Liang, Wan, Jie, Abdelaziz, Mohamod Hamed, Su, Zhaoliang, Wang, Shengjun, Xu, Huaxi

“…Among the major bacterial secretions, outer membrane vesicles (OMVs) are significant and highly functional. The proteins and other biomolecules identified…”
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The innate resistome of “recalcitrant” Acinetobacter baumannii and the role of nanoparticles in combating these MDR pathogens by Aparna, Vasudevan, Dineshkumar, Kesavan, Su, Zhaoliang, Wang, Shengjun, Xu, Huaxi

“…Acinetobacter baumannii , a nosocomial pathogen, and member of ESKAPE bacteria are currently a global threat. A. baumannii is equipped naturally laden with…”
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Ligand Based-Pharmacophore Modeling and Extended Bi oactivity Prediction for Salinosporamide A, B and C from Marine Actino mycetes Salinispora tropica by Dineshkumar, Kesavan, Vasudevan, Aparna, Hopper, Waheeta

“…Actinomycetes produce structurally unique secondary metabolites with pharmaceutically essential bioactivities. Salinispora, an obligate marine actinomycete,…”
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Vesicle-Mediated Dendritic Cell Activation in Acinetobacter baumannii Clinical Isolate, which Contributes to Th2 Response by Xu, Huaxi, Wang, Shengjun, Abdelaziz, Mohamed Hamed, Wan, Jie, Wang, Huixuan, Vasudevan, Aparna, Cheng, Jianjun, Kesavan, Dinesh Kumar, Cai, Wei, Su, Zhaoliang

“…Acinetobacter baumannii, as a nonfermentation Gram-negative bacterium, mainly cause nosocomial infections in critically ill patients. With the widespread of…”
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Genome and Transcriptome Analysis of A. baumannii's “Transient” Increase in Drug Resistance under Tigecycline Pressure by Cheng, Jianjun, Kesavan, Dinesh Kumar, Vasudevan, Aparna, Cai, Wei, Wang, Huixuan, Su, Zhaoliang, Wang, Shengjun, Xu, Huaxi

“…•Completed the process of drug resistance enhancement and recovery of Acinetobacter baumannii in vitro, further understanding the phenomenon of drug…”
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Proteomic Network of Antibiotic-Induced Outer Membrane Vesicles Released by Extensively Drug-Resistant Elizabethkingia anophelis by Chiang, Ming-Hsien, Chang, Fang-Ju, Kesavan, Dinesh Kumar, Vasudevan, Aparna, Xu, Huaxi, Lan, Kuo-Lun, Huang, Shu-Wei, Shang, Hung-Sheng, Chuang, Yi-Ping, Yang, Ya-Sung, Chen, Te-Li

“…Elizabethkingia anophelis, a nonfermenting Gram-negative bacterium, causes life-threatening health care-associated infections. E. anophelis harbors multidrug…”
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Anti-Inflammatory Property of n-Hexadecanoic Acid: Structural Evidence and Kinetic Assessment by Aparna, Vasudevan, Dileep, Kalarickal V., Mandal, Pradeep K., Karthe, Ponnuraj, Sadasivan, Chittalakkottu, Haridas, Madathilkovilakathu

“…Ester bond hydrolysis of membrane phospholipids by Phospholipase A2 and consequent release of fatty acids are the initiating steps of inflammation. It is…”
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In Silico and In Vitro Screening of Natural Compounds as Broad-Spectrum β-Lactamase Inhibitors against Acinetobacter baumannii New Delhi Metallo-β-lactamase-1 (NDM-1) by Vasudevan, Aparna, Kesavan, Dinesh Kumar, Wu, Liang, Su, Zhaoliang, Wang, Shengjun, Ramasamy, Mohan Kumar, Hopper, Waheeta, Xu, Huaxi

“…Antibiotic resistance is one of the significant problems globally; there is an increase in resistance with introducing every new class of antibiotics. Further,…”
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HMGB1-induced ILC2s activate dendritic cells by producing IL-9 in asthmatic mouse model by Wan, Jie, Huang, Lan, Ji, Xiaoyun, Yao, Shun, Hamed Abdelaziz, Mohamed, Cai, Wei, Wang, Huixuan, Cheng, Jianjun, Dineshkumar, Kesavan, Aparna, Vasudevan, Su, Zhaoliang, Wang, Shengjun, Xu, Huaxi

“…•HMGB1 is increased in asthma mice.•HMGB1 can promote ILC2 to secrete IL-9.•Up-regulated ILC2s-derived IL-9 can activate dendritic cells in asthma. Asthma is a…”
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Biological Activity of Sporolides A and B from Salinispora tropica: in silico Target Prediction Using Ligand-Based Pharmacophore Mapping and in vitro activity Validation on HIV-1 Reverse Transcriptase by Dineshkumar, Kesavan, Aparna, Vasudevan, Madhuri, Kantilal Z., Hopper, Waheeta

“…Sporolides A and B are novel polycyclic macrolides from the obligate marine actinomycetes, Salinispora tropica. The unique and novel structure of sporolides…”
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Characterization and distribution of drug resistance associated β-lactamase, membrane porin and efflux pump genes in MDR A. baumannii isolated from Zhenjiang, China by Yang, Huijian, Huang, Lan, Barnie, Prince Amoah, Su, Zhaoliang, Mi, Zuhuang, Chen, Jianguo, Aparna, Vasudevan, Kumar, Dinesh, Xu, Huaxi

“…Acinetobacter baumannii (A. baumannii), especially the multidrug resistant A. baumannii (MDR-AB) is becoming a common opportunistic pathogen in hospital, and…”
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