Search Results - "Vasudeva, Raghavendra"

Interim results of a prospective, randomized, open-label, Phase 3 study of the long-term safety and efficacy of lasmiditan for acute treatment of migraine (the GLADIATOR study) by Brandes, Jan Lewis, Klise, Suzanne, Krege, John H, Case, Michael, Khanna, Rashna, Vasudeva, Raghavendra, Raskin, Joel, Pearlman, Eric M, Kudrow, David

“…To address the need for long-term lasmiditan data, the GLADIATOR study evaluated the safety (primary) and efficacy (secondary) of lasmiditan for the…”
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Mapping the Glyco-Gold Nanoparticles of Different Shapes Toxicity, Biodistribution and Sequestration in Adult Zebrafish by Sangabathuni, Sivakoti, Murthy, Raghavendra Vasudeva, Chaudhary, Preeti Madhukar, Subramani, Balamurugan, Toraskar, Suraj, Kikkeri, Raghavendra

“…Glyconanotechnology offers a broad range of applications across basic and translation research. Despite the tremendous progress in glyco-nanomaterials, there…”
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Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy by Raghavendra, Vasudeva, Tanga, Flobert, DeLeo, Joyce A

“…Microglia, the intrinsic macrophages of the central nervous system, have previously been shown to be activated in the spinal cord in several rat mononeuropathy…”
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A rationally designed peptidomimetic biosensor for sialic acid on cell surfaces by Chaudhary, Preeti Madhukar, Murthy, Raghavendra Vasudeva, Yadav, Rohan, Kikkeri, Raghavendra

“…We have developed peptidomimetic sialic acid (Sia) biosensors using boronic acid and arginine groups on the peptide backbone. The designed peptides were…”
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Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS by Raghavendra, Vasudeva, Tanga, Flobert Y., DeLeo, Joyce A.

“…Peripheral inflammation induces central sensitization characterized by the development of allodynia and hyperalgesia to mechanical and thermal stimuli. Recent…”
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A close association of freedom from pain, migraine-related functional disability, and other outcomes: results of a post hoc analysis of randomized lasmiditan studies SAMURAI and SPARTAN by Lipton, Richard B., Baygani, Simin K., Tepper, Stewart J., Krege, John H., Vasudeva, Raghavendra, Pearlman, Eric M., Hauck, Paula M., Loo, Li Shen

“…Background While pain freedom at 2 h is a key primary outcome for current trials for acute treatment of migraine, the relationship between the degree of head…”
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The Role of Spinal Neuroimmune Activation in Morphine Tolerance/Hyperalgesia in Neuropathic and Sham-Operated Rats by Raghavendra, Vasudeva, Rutkowski, Maria D, DeLeo, Joyce A

“…Hypersensitivity resulting from nerve injury or morphine tolerance/hyperalgesia is predicted to involve similar cellular and molecular mechanisms. One expected…”
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Attenuation of Morphine Tolerance, Withdrawal-Induced Hyperalgesia, and Associated Spinal Inflammatory Immune Responses by Propentofylline in Rats by RAGHAVENDRA, Vasudeva, TANGA, Flobert Y, DELEO, Joyce A

“…The activation of glial cells and enhanced proinflammatory cytokine expression at the spinal cord has been implicated in the development of morphine tolerance,…”
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Immobilization of multivalent glycoprobes on gold surfaces for sensing proteins and macrophages by Gade, Madhuri, Khandelwal, Puneet, Sangabathuni, Sivakoti, Bavireddi, Harikrishna, Murthy, Raghavendra Vasudeva, Poddar, Pankaj, Kikkeri, Raghavendra

“…The multivalent display of carbohydrates on the cell surface provides cooperative binding to improve the specific biological events. In addition to…”
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Perfluoroalkylchain conjugation as a new tactic for enhancing cell permeability of peptide nucleic acids (PNAs) via reducing the nanoparticle size by Ellipilli, Satheesh, vasudeva Murthy, Raghavendra, Ganesh, Krishna N

“…Perfluoro undecanoyl chain conjugated peptide nucleic acids (PNAs) show 2.5 to 3 fold higher cellular uptake efficiency in NIH 3T3 and HeLa cells compared to…”
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Glyco-gold nanoparticle shapes enhance carbohydrate-protein interactions in mammalian cells by Sangabathuni, Sivakoti, Vasudeva Murthy, Raghavendra, Chaudhary, Preeti Madhukar, Surve, Manalee, Banerjee, Anirban, Kikkeri, Raghavendra

“…Advances in shape-dependent nanoparticle (NP) research have prompted a close scrutiny of the behaviour of nanostructures in vitro and in vivo. Data pertaining…”
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Long-term safety and efficacy of lasmiditan for acute treatment of migraine: Final results of the GLADIATOR study by Brandes, Jan Lewis, Klise, Suzanne, Krege, John H, Case, Michael, Khanna, Rashna, Vasudeva, Raghavendra, Raskin, Joel, Kudrow, David

“…GLADIATOR was a prospective, randomized, open-label, phase 3 study of lasmiditan 100 mg or 200 mg dosed intermittently for up to 1 year in patients with…”
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Exploiting the Lactose-GM3 Interaction for Drug Delivery by Murthy, Raghavendra Vasudeva, Bavireddi, Harikrishna, Gade, Madhuri, Kikkeri, Raghavendra

“…Protein–protein and protein–carbohydrate interactions as a means to target the cell surface for therapeutic applications have been extensively investigated…”
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Anti-hyperalgesic and morphine-sparing actions of propentofylline following peripheral nerve injury in rats: mechanistic implications of spinal glia and proinflammatory cytokines by Raghavendra, Vasudeva, Tanga, Flobert, Rutkowski, Maria D, DeLeo, Joyce A

“…Injury to peripheral nerves often produces non-physiological, long-lasting spontaneous pain, hyperalgesia and allodynia that are refractory to standard…”
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Legumain Expression in Relation to Clinicopathologic and Biological Variables in Colorectal Cancer by RAGHAVENDRA VASUDEVA MURTHY, ARBMAN, Gunnar, JINGFANG GAO, ROODMAN, G. David, SUN, Xiao-Feng

“…Purpose: Legumain, a novel asparaginyl endopeptidase, has been observed to be highly expressed in several types of tumors including colorectal cancer. However,…”
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Supramolecular metalloglycodendrimers selectively modulate lectin binding and delivery of Ru(ii) complexes into mammalian cells by Bavireddi, Harikrishna, Vasudeva Murthy, Raghavendra, Gade, Madhuri, Sangabathuni, Sivakoti, Kikkeri, Raghavendra

“…A host-guest interaction between Ru(ii)-complexes and sugar-capped β-cyclodextrin was employed to synthesize metalloglycodendrimers. These glycodendrimers…”
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Possible antioxidant mechanism in melatonin reversal of aging and chronic ethanol-induced amnesia in plus-maze and passive avoidance memory tasks by Raghavendra, Vasudeva, Kulkarni, Shrinivas K

“…Cognitive dysfunction is one of the most striking age-related impairments seen in human beings and animals. This impairment probably is due to the…”
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Recent advances in the metallo-glycodendrimers and its potential applications by Khan, Shadab Ali, Adak, Anindita, Vasudeva Murthy, Raghavendra, Kikkeri, Raghavendra

“…Development of a facile synthesis of optical, electrochemical and radioactive glycodendrimers promises to greatly impact the investigation of weak…”
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Lasmiditan Efficacy in Mild Versus Moderate or Severe Migraine Headaches (1811) by Vincent, Maurice, Peres, Mario, Vasudeva, Raghavendra, Baygani, Simin, Dennehy, Ellen, Friedman, Deborah

“…Abstract only…”
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Sialic Acid Hydroxamate: A Potential Antioxidant and Inhibitor of Metal-Induced [beta]-Amyloid Aggregates by Yadav, Rohan, Murthy, Raghavendra Vasudeva, Kikkeri, Raghavendra

“…Current methods for Alzheimer's treatment require a three-component system: metal chelators, antioxidants, and amyloid [beta] (A[beta])-peptide-binding…”
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