Search Results - "Vasta, R."

Galectins as pattern recognition receptors: structure, function, and evolution by Vasta, Gerardo R

“…Galectins constitute an evolutionary conserved family of ß-galactoside-binding proteins, ubiquitous in mammals and other vertebrate taxa, invertebrates, and…”
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Binding of a C-type lectin's coiled-coil domain to the Domeless receptor directly activates the JAK/STAT pathway in the shrimp immune response to bacterial infection by Sun, Jie-Jie, Lan, Jiang-Feng, Zhao, Xiao-Fan, Vasta, Gerardo R, Wang, Jin-Xing

“…C-type lectins (CTLs) are characterized by the presence of a C-type carbohydrate recognition domain (CTLD) that by recognizing microbial glycans, is…”
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A Galectin of Unique Domain Organization from Hemocytes of the Eastern Oyster (Crassostrea virginica) Is a Receptor for the Protistan Parasite Perkinsus marinus by Tasumi, Satoshi, Vasta, Gerardo R

“…Invertebrates display effective innate immune responses for defense against microbial infection. However, the protozoan parasite Perkinsus marinus causes Dermo…”
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When Galectins Recognize Glycans: From Biochemistry to Physiology and Back Again by Di Lella, Santiago, Sundblad, Victoria, Cerliani, Juan P, Guardia, Carlos M, Estrin, Dario A, Vasta, Gerardo R, Rabinovich, Gabriel A

“…In the past decade, increasing efforts have been devoted to the study of galectins, a family of evolutionarily conserved glycan-binding proteins with…”
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Galectins: matricellular glycan-binding proteins linking cell adhesion, migration, and survival by Elola, M. T, Wolfenstein-Todel, C, Troncoso, M. F, Vasta, G. R, Rabinovich, G. A

“…Galectins are a taxonomically widespread family of glycan-binding proteins, defined by at least one conserved carbohydrate-recognition domain with a canonical…”
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Scavenger receptor B2, a type III membrane pattern recognition receptor, senses LPS and activates the IMD pathway in crustaceans by Shi, Xiu-Zhen, Yang, Ming-Chong, Kang, Xin-Le, Li, Yan-Xue, Hong, Pan-Pan, Zhao, Xiao-Fan, Vasta, Gerardo R, Wang, Jin-Xing

“…The immune deficiency (IMD) pathway is critical for elevating host immunity in both insects and crustaceans. The IMD pathway activation in insects is mediated…”
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Pregnancy Galectinology: Insights Into a Complex Network of Glycan Binding Proteins by Blois, Sandra M, Dveksler, Gabriela, Vasta, Gerardo R, Freitag, Nancy, Blanchard, Véronique, Barrientos, Gabriela

“…Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins, consisting of 15 different types, each with a specific function…”
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Galectins regulate the inflammatory response in airway epithelial cells exposed to microbial neuraminidase by modulating the expression of SOCS1 and RIG1 by Nita-Lazar, Mihai, Banerjee, Aditi, Feng, Chiguang, Vasta, Gerardo R.

“…•Microbial neuraminidases unmask galectin ligands at the airway epithelial surface.•Galectin 1 and galectin 3 modulate the expression of SOCS1 and…”
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DYNAMITE: Integrating Archetypal Analysis and Process Mining for Interpretable Disease Progression Modelling by Trescato, I., Tavazzi, E., Vettoretti, M., Gatta, R., Vasta, R., Chio, A., Camillo, B. Di

“…DYNAMITE, an acronym for DYNamic Archetypal analysis for MIning disease TrajEctories, is a new methodology developed specifically to model disease progression…”
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Gender effect on non-motor symptoms in Parkinson's disease: A men more at risk? by Nicoletti, A, Vasta, R, Mostile, G, Nicoletti, G, Arabia, G, Iliceto, G, Lamberti, P, Marconi, R, Morgante, L, Barone, P, Quattrone, A, Zappia, M

“…Abstract Introduction Several gender differences have been reported in Parkinson's Disease (PD). We evaluated the burden of non-motor symptoms (NMS) in PD and…”
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Functions of galectins as ‘self/non-self’-recognition and effector factors by Vasta, Gerardo R., Feng, Chiguang, González-Montalbán, Nuria, Mancini, Justin, Yang, Lishi, Abernathy, Kelsey, Frost, Graeme, Palm, Cheyenne

“…Abstract Carbohydrate structures on the cell surface encode complex information that through specific recognition by carbohydrate-binding proteins (lectins)…”
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Cod glycopeptide with picomolar affinity to galectin-3 suppresses T-cell apoptosis and prostate cancer metastasis by Guha, Prasun, Kaptan, Engin, Bandyopadhyaya, Gargi, Kaczanowska, Sabina, Davila, Eduardo, Thompson, Keyata, Martin, Stuart S., Kalvakolanu, Dhananjaya V., Vasta, Gerardo R., Ahmed, Hafiz

“…Cancer metastasis and immune suppression are critical issues in cancer therapy. Here, we show that a β-galactoside–binding lectin [galectin-3 (gal3)] that…”
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Structural and functional diversity of the lectin repertoire in teleost fish: Relevance to innate and adaptive immunity by Vasta, Gerardo R., Nita-Lazar, Mihai, Giomarelli, Barbara, Ahmed, Hafiz, Du, Shaojun, Cammarata, Matteo, Parrinello, Nicolò, Bianchet, Mario A., Amzel, L. Mario

“…Protein–carbohydrate interactions mediated by lectins have been recognized as key components of innate immunity in vertebrates and invertebrates, not only for…”
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Desialylation of airway epithelial cells during influenza virus infection enhances pneumococcal adhesion via galectin binding by Nita-Lazar, Mihai, Banerjee, Aditi, Feng, Chiguang, Amin, Mohammed N., Frieman, Matthew B., Chen, Wilbur H., Cross, Alan S., Wang, Lai-Xi, Vasta, Gerardo R.

“…•We studied the role of galectins in pneumococcal adhesion in the lung upon influenza.•After influenza, galectin-1 and -3 levels are increased in the…”
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Editorial: The role of glycans in infectious disease, Volume II by Martínez-Duncker, Iván, Mora-Montes, Héctor M., Vasta, Gerardo R., Chiodo, Fabrizio

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Editorial: The Role of Glycans in Infectious Disease by Martínez-Duncker, Iván, Chiodo, Fabrizio, Mora-Montes, Héctor M, Vasta, Gerardo R

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F-Type Lectins: A Highly Diversified Family of Fucose-Binding Proteins with a Unique Sequence Motif and Structural Fold, Involved in Self/Non-Self-Recognition by Vasta, Gerardo R, Amzel, L Mario, Bianchet, Mario A, Cammarata, Matteo, Feng, Chiguang, Saito, Keiko

“…The F-type lectin (FTL) family is one of the most recent to be identified and structurally characterized. Members of the FTL family are characterized by a…”
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Structural and functional diversity of lectin repertoires in invertebrates, protochordates and ectothermic vertebrates by Vasta, Gerardo R, Ahmed, Hafiz, Odom, Eric W

“…During the past few years, substantial progress has been accomplished in the elucidation of the structural diversity of the lectin repertoires of…”
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Protozoan parasites of bivalve molluscs: literature follows culture by Fernández Robledo, José A, Vasta, Gerardo R, Record, Nicholas R

“…Bivalve molluscs are key components of the estuarine environments as contributors to the trophic chain, and as filter -feeders, for maintaining ecosystem…”
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Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3 by Wang, Helen, Huang, Wei, Orwenyo, Jared, Banerjee, Aditi, Vasta, Gerardo R., Wang, Lai-Xi

“…We report a facile synthesis of glycoprotein-based glyco-ligands and their binding with influenza hemagglutinin and human galectin-3. Human serum albumin (HSA)…”
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