Search Results - "Vassura, Marco"
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Blurring contact maps of thousands of proteins: what we can learn by reconstructing 3D structure
Published in BioData mining (13-01-2011)“…The present knowledge of protein structures at atomic level derives from some 60,000 molecules. Yet the exponential ever growing set of hypothetical protein…”
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On the Reconstruction of Three-dimensional Protein Structures from Contact Maps
Published in Algorithms (01-03-2009)“…The problem of protein structure prediction is one of the long-standing goals of Computational Biology. Although we are still not able to provide first…”
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Journal Article Book Review -
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Correlating disease-related mutations to their effect on protein stability: A large-scale analysis of the human proteome
Published in Human mutation (01-10-2011)“…Single residue mutations in proteins are known to affect protein stability and function. As a consequence, they can be disease associated. Available…”
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FT-COMAR: fault tolerant three-dimensional structure reconstruction from protein contact maps
Published in Bioinformatics (15-05-2008)“…Fault Tolerant Contact Map Reconstruction (FT-COMAR) is a heuristic algorithm for the reconstruction of the protein three-dimensional structure from (possibly)…”
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Fast overlapping of protein contact maps by alignment of eigenvectors
Published in Bioinformatics (15-09-2010)“…Motivation: Searching for structural similarity is a key issue of protein functional annotation. The maximum contact map overlap (CMO) is one of the possible…”
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Reconstruction of 3D Structures From Protein Contact Maps
Published in IEEE/ACM transactions on computational biology and bioinformatics (01-07-2008)“…The prediction of the protein tertiary structure from solely its residue sequence (the so called Protein Folding Problem) is one of the most challenging…”
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A graph theoretic approach to protein structure selection
Published in Artificial intelligence in medicine (01-02-2009)“…Summary Objective Protein structure prediction (PSP) aims to reconstruct the 3D structure of a given protein starting from its primary structure (chain of…”
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Is There an Optimal Substitution Matrix for Contact Prediction with Correlated Mutations?
Published in IEEE/ACM transactions on computational biology and bioinformatics (01-07-2011)“…Correlated mutations in proteins are believed to occur in order to preserve the protein functional folding through evolution. Their values can be deduced from…”
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