Search Results - "Vasko, Vasyl V."

Metformin targets Mitochondrial Glycerophosphate Dehydrogenase (mGPDH) to control Rate of Oxidative Phosphorylation and growth of thyroid cancer in vitro and in vivo by Thakur, Shilpa, Daley, Brianna, Gaskins, Kelli, Vasko, Vasyl V, Boufraqech, Myriem, Patel, Dhaval, Sourbier, Carole, Reece, Jeff M, Cheng, Sheue-Yann, Kebebew, Electron, Agarwal, Sunita K, Klubo-Gwiezdzinska, Joanna

“…Mitochondrial glycerophosphate dehydrogenase (mGPDH) is the key enzyme connecting oxidative phosphorylation (OXPHOS) and glycolysis as well as a target of the…”
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Phase II Trial of Sorafenib in Metastatic Thyroid Cancer by KLOOS, Richard T, RINGEL, Matthew D, RITTENBERRY, Jennifer, LAI WEI, ARBOGAST, Daria, COLLAMORE, Minden, WRIGHT, John J, GREVER, Michael, SHAH, Manisha H, KNOPP, Michael V, HALL, Nathan C, KING, Mark, STEVENS, Robert, JIACHAO LIANG, WAKELY, Paul E, VASKO, Vasyl V, SAJI, Motoyasu

“…Based on the pivotal role of Ras-Raf-MAP-ERK signaling and vascular endothelial growth factor (VEGF) in papillary thyroid cancer (PTC), we conducted a phase II…”
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Phase II Clinical Trial of Sorafenib in Metastatic Medullary Thyroid Cancer by Lam, Elaine T, Ringel, Matthew D, Kloos, Richard T, Prior, Thomas W, Knopp, Michael V, Liang, Jiachao, Sammet, Steffen, Hall, Nathan C, Wakely, Jr, Paul E, Vasko, Vasyl V, Saji, Motoyasu, Snyder, Pamela J, Wei, Lai, Arbogast, Daria, Collamore, Minden, Wright, John J, Moley, Jeffrey F, Villalona-Calero, Miguel A, Shah, Manisha H

“…Mutations in the RET proto-oncogene and vascular endothelial growth factor receptor (VEGFR) activity are critical in the pathogenesis of medullary thyroid…”
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PKA Activates AMPK Through LKB1 Signaling in Follicular Thyroid Cancer by Kari, Suresh, Vasko, Vasyl V, Priya, Shivam, Kirschner, Lawrence S

“…Thyroid cancer affects about one percent of the population, and has seen rising incidence in recent years. Follicular thyroid cancer (FTC) comprises 10-15% of…”
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Microfluidic Droplet Digital PCR Is a Powerful Tool for Detection of BRAF and TERT Mutations in Papillary Thyroid Carcinomas by Ylli, Dorina, Patel, Aneeta, Jensen, Kirk, Li, Zhao-Zhang, Mendonca-Torres, Maria Cecilia, Costello, John, Gomes-Lima, Cristiane Jeyce, Wartofsky, Leonard, Burman, Kenneth Dale, Vasko, Vasyl V

“…We examined the utility of microfluidic digital PCR (dPCR) for detection of and mutations in thyroid tumors. DNA extracted from 100 thyroid tumors (10…”
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Group I p21-activated kinases regulate thyroid cancer cell migration and are overexpressed and activated in thyroid cancer invasion by McCarty, Samantha K, Saji, Motoyasu, Zhang, Xiaoli, Jarjoura, David, Fusco, Alfredo, Vasko, Vasyl V, Ringel, Matthew D

“…p21-activated kinases (PAKs) are a family of serine/threonine kinases that regulate cytoskeletal dynamics and cell motility. PAKs are subdivided into group I…”
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Molecular mechanisms involved in differentiated thyroid cancer invasion and metastasis by Vasko, Vasyl V, Saji, Motoyasu

“…PURPOSE OF REVIEWThe majority of patients with thyroid cancer have an excellent prognosis, however patients with extensive local invasion and distant…”
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Detection of BRAFV600E in Liquid Biopsy from Patients with Papillary Thyroid Cancer Is Associated with Tumor Aggressiveness and Response to Therapy by Jensen, Kirk, Thakur, Shilpa, Patel, Aneeta, Mendonca-Torres, Maria Cecilia, Costello, John, Gomes-Lima, Cristiane Jeyce, Walter, Mary, Wartofsky, Leonard, Burman, Kenneth Dale, Bikas, Athanasios, Ylli, Dorina, Vasko, Vasyl V., Klubo-Gwiezdzinska, Joanna

“…The detection of rare mutational targets in plasma (liquid biopsy) has emerged as a promising tool for the assessment of patients with cancer. We determined…”
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The expression of translocator protein in human thyroid cancer and its role in the response of thyroid cancer cells to oxidative stress by Klubo-Gwiezdzinska, Joanna, Jensen, Kirk, Bauer, Andrew, Patel, Aneeta, Costello, John, Burman, Kenneth D, Wartofsky, Leonard, Hardwick, Matthew J, Vasko, Vasyl V

“…The translocator protein (TSPO), formerly known as a peripheral benzodiazepine receptor, exerts pro-apoptotic function via regulation of mitochondrial membrane…”
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Abstract 1001: Expression of cytochrome C oxidase 4 (COX4) in thyroid cancer cells by Vasko, Vasyl V., Bikas, Athanasios, Patel, Aneeta, Costello, John, Tkavc, Rok, Burman, Kenneth D., Jensen, Kirk

“…Background: Targeting cell metabolism has emerged as a therapeutic strategy for the treatment of cancer. Metabolically active thyroid cancers are resistant to…”
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MON-514 Detection of RAS Mutations and RET/PTC Fusions in Thyroid Cancer Using Microfluidic Digital PCR by Ylli, Dorina, Patel, Aneeta, Mendoca-Torres, Maria Cecilia, Costello, John, Bikas, Athanasios, Wartofsky, Leonard, Burman, Kenneth D, Jensen, Kirk, Vasko, Vasyl V

“…Background: The identification of somatic mutations and gene fusions is crucial for guiding therapeutic decisions in patients with thyroid cancer. Microfluidic…”
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Abstract 5348: Detection of herpes simplex viruses in thyroid cancer by Vasko, Vasyl V., Jensen, Kirk, Patel, Aneeta, Bauer, Andrew

“…Introduction: There is limited information about the role of herpesviridae viruses in thyroid cancer. Materials and Methods: Thyroid tissues from 109 patients…”
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