Search Results - "Vasilopoulou, Elisavet"
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The Pathophysiological Role of Thymosin β4 in the Kidney Glomerulus
Published in International journal of molecular sciences (22-04-2023)“…Diseases affecting the glomerulus, the filtration unit of the kidney, are a major cause of chronic kidney disease. Glomerular disease is characterised by…”
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Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice
Published in Scientific reports (16-07-2022)“…Plasma ultrafiltration in the kidney occurs across glomerular capillaries, which are surrounded by epithelial cells called podocytes. Podocytes have a unique…”
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3
Cardiotrophin‐1 therapy reduces disease severity in a murine model of glomerular disease
Published in Physiological reports (01-07-2024)“…Cardiotrophin‐1 (CT‐1), a member of the interleukin (IL)‐6 cytokine family, has renoprotective effects in mouse models of acute kidney disease and…”
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4
Monocarboxylate transporter 8 modulates the viability and invasive capacity of human placental cells and fetoplacental growth in mice
Published in PloS one (12-06-2013)“…Monocarboxylate transporter 8 (MCT8) is a well-established thyroid hormone (TH) transporter. In humans, MCT8 mutations result in changes in circulating TH…”
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Isolating and Culturing Mouse Podocyte Cells to Study Diabetic Nephropathy
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…Diabetic nephropathy is associated with injury and loss of podocytes, specialized epithelial cells that are critical for glomerular filtration. This chapter…”
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Thymosin-β4: A key modifier of renal disease
Published in Expert opinion on biological therapy (31-05-2018)“…There is an urgent need for new treatments for chronic kidney disease (CKD). Thymosin-β4 is a peptide that reduces inflammation and fibrosis and has the…”
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The role of the placenta in thyroid hormone delivery to the fetus
Published in Nature clinical practice. Endocrinology & metabolism (01-01-2009)“…The passage of thyroid hormones from the maternal circulation to the fetal circulation is important for normal fetal development. This Review discusses the…”
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Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury
Published in The Journal of pathology (01-12-2018)“…Planar cell polarity (PCP) pathways control the orientation and alignment of epithelial cells within tissues. Van Gogh‐like 2 (Vangl2) is a key PCP protein…”
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MP207ROLE OF CARDIOTROPHIN-1 IN GLOMERULAR DAMAGE AND PODOCYTE BIOLOGY
Published in Nephrology, dialysis, transplantation (01-05-2017)Get full text
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10
The role of thymosin-β4 in kidney disease
Published in Expert opinion on biological therapy (2015)“…Therapies that modulate inflammation and fibrosis have the potential to reduce the morbidity and mortality associated with chronic kidney disease (CKD). A…”
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Loss of endogenous thymosin β 4 accelerates glomerular disease
Published in Kidney international (01-11-2016)“…Glomerular disease is characterized by morphologic changes in podocyte cells accompanied by inflammation and fibrosis. Thymosin β regulates cell morphology,…”
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The role of thyroid hormones in placental development and the importance of the thyroid hormone transporter mct8
Published 01-01-2010“…Thyroid hormones (THs) are important for fetoplacental development. Human intrauterine growth restriction (IUGR) is associated with malplacentation and reduced…”
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