Variation of morphophysiological and genetic demographic traits in children with congenital cleft lip and palate

Medical records and questionnaire data have been used to analyze morphophysiological (the birth weight and length) and genetic demographic (maternal age and marriage structure) traits in a sample of children with orofacial malformations (OMs, cleft palate and/or cleft lip) living in Krasnodar krai,...

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Bibliographic Details
Published in:	Genetika Vol. 47; no. 11; p. 1514
Main Authors:	Kurbatova, O L, Vasiliev, Iu A, Prudnikova, A S, Pobedonostseva, E Iu, Uchaeva, V S, Varapatvelian, A F, Udina, I G
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-11-2011
Subjects:	Adolescent Body Weights and Measures Child Child, Preschool Cleft Lip - epidemiology Cleft Lip - genetics Cleft Palate - epidemiology Cleft Palate - genetics Demography Female Humans Infant Male Maternal Age Russia - epidemiology Russia
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Summary:	Medical records and questionnaire data have been used to analyze morphophysiological (the birth weight and length) and genetic demographic (maternal age and marriage structure) traits in a sample of children with orofacial malformations (OMs, cleft palate and/or cleft lip) living in Krasnodar krai, Russia. The sample of children with malformations (including premature infants) differs from the control group in lower birth weight and length and a lower proportion of children with morphophysiological values close to the population average values, as well as a higher family exogamy level estimated on the basis of marriage structure in the parental and preceding generations. The risk of congenital cleft palate and/or cleft lip is considerably increased if the material age is over 35 years or, to a lower degree, if it is under 20 years.
ISSN:	0016-6758