Untoward side effects of chemoradiotherapy in children with malignant brain tumors

Untoward side-effects of chemoradiotherapy were compared in 48 children treated for brain tumors and those in remission lasting from less than 12 months to 11 years. The investigation concerned disturbances in the neurologic, endocrine, cardiovascular, urinary, hepatobiliary and psychic systems; neu...

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Bibliographic Details
Published in:	Voprosy onkologij Vol. 48; no. 3; p. 361
Main Authors:	Morozova, S K, Begun, I V, Spivak, L V, Radiuk, K A, Papkevich, I I, Savich, T V, Pershaĭ, E B, Vashkevich, T I, Aleĭnikova, O V
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 2002
Subjects:	Adolescent Analysis of Variance Brain Neoplasms - drug therapy Brain Neoplasms - radiotherapy Cardiovascular Diseases - chemically induced Cardiovascular Diseases - etiology Child Child, Preschool Drug-Related Side Effects and Adverse Reactions Female Hormones - blood Humans Immunoenzyme Techniques Male Mental Disorders - chemically induced Mental Disorders - etiology Nervous System Diseases - chemically induced Nervous System Diseases - etiology Radiotherapy - adverse effects Radiotherapy Dosage Remission Induction Thyroid Gland - drug effects Thyroid Gland - radiation effects Time Factors
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Summary:	Untoward side-effects of chemoradiotherapy were compared in 48 children treated for brain tumors and those in remission lasting from less than 12 months to 11 years. The investigation concerned disturbances in the neurologic, endocrine, cardiovascular, urinary, hepatobiliary and psychic systems; neurologic ones proved the most frequent. No cases of heart failure were reported among patients with brain tumors during remission. Hormonal study revealed inhibited thyroid function in brain tumor sufferers.
ISSN:	0507-3758