Search Results - "Vasen, Hans FA"

Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia by Schubert, Stephanie A, Ruano, Dina, Elsayed, Fadwa A, Boot, Arnoud, Crobach, Stijn, Sarasqueta, Arantza Farina, Wolffenbuttel, Bruce, van der Klauw, Melanie M, Oosting, Jan, Tops, Carli M, van Eijk, Ronald, Vasen, Hans FA, Vossen, Rolf HAM, Nielsen, Maartje, Castellví-Bel, Sergi, Ruiz-Ponte, Clara, Tomlinson, Ian, Dunlop, Malcolm G, Vodicka, Pavel, Wijnen, Juul T, Hes, Frederik J, Morreau, Hans, de Miranda, Noel FCC, Sijmons, Rolf H, van Wezel, Tom

“…Background: A substantial fraction of familial colorectal cancer (CRC) and polyposis heritability remains unexplained. This study aimed to identify…”
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Erratum: Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia by Schubert, Stephanie A, Ruano, Dina, Elsayed, Fadwa A, Boot, Arnoud, Crobach, Stijn, Sarasqueta, Arantza Farina, Wolffenbuttel, Bruce, van der Klauw, Melanie M, Oosting, Jan, Tops, Carli M, van Eijk, Ronald, Vasen, Hans FA, Vossen, Rolf HAM, Nielsen, Maartje, Castellví-Bel, Sergi, Ruiz-Ponte, Clara, Tomlinson, Ian, Dunlop, Malcolm G, Vodicka, Pavel, Wijnen, Juul T, Hes, Frederik J, Morreau, Hans, de Miranda, Noel FCC, Sijmons, Rolf H, van Wezel, Tom

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Small-bowel cancer in Lynch syndrome: is it time for surveillance? by Koornstra, Jan J, Dr, Kleibeuker, Jan H, Prof, Vasen, Hans FA, MD

“…Summary Small-bowel cancer is part of the tumour spectrum of Lynch syndrome. Lynch syndrome, or hereditary non-polyposis colorectal cancer, is caused by…”
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Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas by Nielsen, Maartje, de Miranda, Noel F C C, van Puijenbroek, Marjo, Jordanova, Ekaterina S, Middeldorp, Anneke, van Wezel, Tom, van Eijk, Ronald, Tops, Carli M J, Vasen, Hans F A, Hes, Frederik J, Morreau, Hans

“…MUTYH-associated polyposis (MAP) is a recessively inherited disorder which predisposes biallelic carriers for a high risk of polyposis and colorectal carcinoma…”
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Cost-utility analysis of genetic screening in families of patients with germline MUTYH mutations by Nielsen, Maartje, Hes, Frederik J, Vasen, Hans F A, van den Hout, Wilbert B

“…MUTYH associated polyposis (MAP) is an autosomal recessive inherited disorder. Carriers of bi-allelic MUTYH germline mutations have a risk of approximately 60%…”
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Chromosome 8q23.3, 10p14 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome – a combined analysis of the Australian, Dutch and Polish Lynch syndrome cohorts by Talseth-Palmer, Bente A, Wijnen, Juul T, Brenne, Ingvild S, Jagmohan-Changur, Shantie, Ashton, Katie A, Tops, Carli M, Evans, Tiffany-Jane, McPhillips, Mary, Groombridge, Claire, Suchy, Janina, Kurzawski, Grzegorz, Spigelman, Allan, Møller, Pål, Morreau, Hans M, Van Wezel, Tom, Lubinski, Jan, Vasen, Hans FA, Scott, Rodney J

“…Doc number: A32…”
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A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer by Middeldorp, Anneke, Jagmohan-Changur, Shantie, Helmer, Quinta, van der Klift, Heleen M, Tops, Carli M J, Vasen, Hans F A, Devilee, Peter, Morreau, Hans, Houwing-Duistermaat, Jeanine J, Wijnen, Juul T, van Wezel, Tom

“…The apparent dominant model of colorectal cancer (CRC) inheritance in several large families, without mutations in known CRC susceptibility genes, suggests the…”
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Twenty-five years of surveillance for familial and hereditary pancreatic ductal adenocarcinoma: Historical perspectives and introduction to the special issue by Vasen, Hans FA, Canto, Marcia Irene, Goggins, Michael

“…In the 1990s, as prevention became a central strategy in the battle against cancer and the molecular genetics revolution uncovered the genetic basis of…”
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The odyssee from surveillance to the detection of pancreatic cancer, total pancreatectomy, and its impact on life. insights from a p16-Leiden pathogenic variant carrier by Spruitenburg, Amarensia (Marit), Vasen, Hans FA

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Loss of ARID1A expression and its relationship with PI3K-Akt pathway alterations, TP53 and microsatellite instability in endometrial cancer by Bosse, Tjalling, ter Haar, Natalja T, Seeber, Laura M, Diest, Paul J v, Hes, Frederik J, Vasen, Hans FA, Nout, Remi A, Creutzberg, Carien L, Morreau, Hans, Smit, Vincent THBM

“…The switch/sucrose non-fermentable (SWI/SNF) subunit ARID1A ( AT-rich interactive domain 1A gene) has been recently postulated as a novel tumor suppressor of…”
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Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer by Elsayed, Fadwa A, Kets, C Marleen, Ruano, Dina, van den Akker, Brendy, Mensenkamp, Arjen R, Schrumpf, Melanie, Nielsen, Maartje, Wijnen, Juul T, Tops, Carli M, Ligtenberg, Marjolijn J, Vasen, Hans F A, Hes, Frederik J, Morreau, Hans, van Wezel, Tom

“…Germline variants affecting the exonuclease domains of POLE and POLD1 predispose to multiple colorectal adenomas and/or colorectal cancer (CRC). The aim of…”
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Extracolonic cancer risk in Dutch patients with APC (adenomatous polyposis coli)-associated polyposis by Ghorbanoghli, Zeinab, Bastiaansen, Barbara Aj, Langers, Alexandra Mj, Nagengast, Fokko M, Poley, Jan-Werner, Hardwick, James Ch, Koornstra, Jan J, Sanduleanu, Silvia, de Vos Tot Nederveen Cappel, Wouter H, Witteman, Ben Jm, Morreau, H, Dekker, Evelien, Vasen, Hans Fa

“…Screening of patients with familial adenomatous polyposis (FAP) have led to a substantial reduction in mortality due to colorectal cancer (CRC). Recent…”
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Inflammatory potential of the diet and colorectal tumor risk in persons with Lynch syndrome by Brouwer, Jesca GM, Makama, Maureen, van Woudenbergh, Geertruida J, Vasen, Hans FA, Nagengast, Fokko M, Kleibeuker, Jan H, Kampman, Ellen, van Duijnhoven, Fränzel JB

“…Persons with Lynch syndrome (LS) have high lifetime risk of developing colorectal tumors (CRTs) because of a germline mutation in one of their mismatch repair…”
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Clinical Utility Gene Card for: Familial adenomatous polyposis (FAP) and attenuated FAP (AFAP)--update 2014 by Aretz, Stefan, Vasen, Hans F A, Olschwang, Sylviane

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Diet quality and colorectal tumor risk in persons with Lynch syndrome by Eijkelboom, Anouk H., Brouwer, Jesca G.M., Vasen, Hans F.A., Bisseling, Tanya M., Koornstra, Jan J., Kampman, Ellen, van Duijnhoven, Fränzel J.B.

“…•Both the Dutch Healthy Diet index 2015 (DHD15-index) and the Dietary Approaches to Stop Hypertension (DASH) score are inversely associated with colorectal…”
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Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia by Schubert, Stephanie A, Ruano, Dina, Elsayed, Fadwa A, Boot, Arnoud, Crobach, Stijn, Sarasqueta, Arantza Farina, Wolffenbuttel, Bruce, van der Klauw, Melanie M, Oosting, Jan, Tops, Carli M, van Eijk, Ronald, Vasen, Hans Fa, Vossen, Rolf Ham, Nielsen, Maartje, Castellví-Bel, Sergi, Ruiz-Ponte, Clara, Tomlinson, Ian, Dunlop, Malcolm G, Vodicka, Pavel, Wijnen, Juul T, Hes, Frederik J, Morreau, Hans, de Miranda, Noel Fcc, Sijmons, Rolf H, van Wezel, Tom

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Equivalent Helicobacter pylori infection rates in Lynch syndrome mutation carriers with and without a first-degree relative with gastric cancer by Soer, Eline C., Leicher, Laura W., Langers, Alexandra M. J., van de Meeberg, Paul C., van der Wouden, Egbert-Jan, Koornstra, Jan Jakob, Bigirwamungu-Bargeman, Marloes, Vasen, Hans F. A., de Vos tot Nederveen Cappel, Wouter H.

“…Background Patients with Lynch syndrome (LS) are at an increased risk of developing gastric cancer. In 2010, a guideline that recommended to screen all…”
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Endoscopic full thickness resection for early colon cancer in Lynch syndrome by Langers, Alexandra M. J., Boonstra, Jurjen J., Hardwick, James C. H., van der Kraan, Jolein, Farina Sarasqueta, Arantza, Vasen, Hans F.A.

“…Subtotal colectomy is usually the therapy of choice in Lynch syndrome patients diagnosed with colon cancer. In patients who develop cancer after the age of…”
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Physical activity and the risk of breast cancer in BRCA1/2 mutation carriers by Pijpe, Anouk, Manders, Peggy, Brohet, Richard M., Collée, J. Margriet, Verhoef, Senno, Vasen, Hans F. A., Hoogerbrugge, Nicoline, van Asperen, Christi J., Dommering, Charlotte, Ausems, Margreet G. E. M., Aalfs, Cora M., Gomez-Garcia, Encarna B., van‘t Veer, Laura J., van Leeuwen, Flora E., Rookus, Matti A.

“…BRCA1/2 mutation carriers have a high lifetime risk of developing breast cancer. Differences in penetrance indicate that this risk may be influenced by…”
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A cell-free assay for the functional analysis of variants of the mismatch repair protein MLH1 by Drost, Mark, Zonneveld, Jos é B.M., van Dijk, Linda, Morreau, Hans, Tops, Carli M., Vasen, Hans F.A., Wijnen, Juul T., de Wind, Niels

“…The hereditary colon and endometrium cancer predisposition Lynch Syndrome (also called HNPCC) is caused by a germ‐line mutation in one of the DNA mismatch…”
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