Search Results - "Vasdekis, Andreas E."

Review of methods to probe single cell metabolism and bioenergetics by Vasdekis, Andreas E., Stephanopoulos, Gregory

“…Single cell investigations have enabled unexpected discoveries, such as the existence of biological noise and phenotypic switching in infection, metabolism and…”
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Deep learning classification of lipid droplets in quantitative phase images by Sheneman, Luke, Stephanopoulos, Gregory, Vasdekis, Andreas E

“…We report the application of supervised machine learning to the automated classification of lipid droplets in label-free, quantitative-phase images. By…”
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Quantitative phase imaging by gradient retardance optical microscopy by Zhang, Jinming, Sarollahi, Mirsaeid, Luckhart, Shirley, Harrison, Maria J., Vasdekis, Andreas E.

“…Quantitative phase imaging (QPI) has become a vital tool in bioimaging, offering precise measurements of wavefront distortion and, thus, of key cellular…”
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Correction: Microbial phenotypic heterogeneity in response to a metabolic toxin: Continuous, dynamically shifting distribution of formaldehyde tolerance in Methylobacterium extorquens populations by Lee, Jessica A, Riazi, Siavash, Nemati, Shahla, Bazurto, Jannell V, Vasdekis, Andreas E, Ridenhour, Benjamin J, Remien, Christopher H, Marx, Christopher J

“…[This corrects the article DOI: 10.1371/journal.pgen.1008458.]…”
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Microbial phenotypic heterogeneity in response to a metabolic toxin: Continuous, dynamically shifting distribution of formaldehyde tolerance in Methylobacterium extorquens populations by Lee, Jessica A, Riazi, Siavash, Nemati, Shahla, Bazurto, Jannell V, Vasdekis, Andreas E, Ridenhour, Benjamin J, Remien, Christopher H, Marx, Christopher J

“…While microbiologists often make the simplifying assumption that genotype determines phenotype in a given environment, it is becoming increasingly apparent…”
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Scattered‐light‐sheet microscopy with sub‐cellular resolving power by Subedi, Nava R., Stolyar, Sergey, Tuson, Sabrina J., Marx, Christopher J., Vasdekis, Andreas E.

“…Since its first demonstration over 100 years ago, scattering‐based light‐sheet microscopy has recently re‐emerged as a key modality in label‐free tissue…”
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Exploiting Bioprocessing Fluctuations to Elicit the Mechanistics of De Novo Lipogenesis in Yarrowia lipolytica by Vasdekis, Andreas E, Silverman, Andrew M, Stephanopoulos, Gregory

“…Despite substantial achievements in elucidating the metabolic pathways of lipogenesis, a mechanistic representation of lipid accumulation and degradation has…”
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Density fluctuations, homeostasis, and reproduction effects in bacteria by Nemati, Shahla, Singh, Abhyudai, Dhuey, Scott D., McDonald, Armando, Weinreich, Daniel M., Vasdekis, Andreas. E.

“…Single-cells grow by increasing their biomass and size. Here, we report that while mass and size accumulation rates of single Escherichia coli cells are…”
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High-Gain Broadband Solid-State Optical Amplifier using a Semiconducting Copolymer by Amarasinghe, Dimali, Ruseckas, Arvydas, Vasdekis, Andreas E., Turnbull, Graham A., Samuel, Ifor D. W.

“…A dilute fluorene copolymer produces enhanced optical amplification. High gain with 1000 times optical amplification and a long lifetime is achieve in only 1mm…”
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Silicon oxide deposition for enhanced optical switching in polydimethylsiloxane-liquid crystal hybrids by De Sio, Luciano, Vasdekis, Andreas E, Cuennet, Julien G, De Luca, Antonio, Pane, Alfredo, Psaltis, Demetri

“…We report an optical switch based on a diffraction grating by combining PDMS microstructures with a photo-responsive Nematic Liquid Crystal (NLC). The grating…”
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Enhancing single molecule imaging in optofluidics and microfluidics by Vasdekis, Andreas E, Laporte, Gregoire P J

“…Microfluidics and optofluidics have revolutionized high-throughput analysis and chemical synthesis over the past decade. Single molecule imaging has witnessed…”
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Microfluidic Assays for DNA Manipulation Based on a Block Copolymer Immobilization Strategy by Vasdekis, Andreas E, O’Neil, Conlin P, Hubbell, Jeffrey A, Psaltis, Demetri

“…Methods to manipulate and visualize isolated DNA and oligonucleotide strands are important for investigation of their biophysics as well as their interactions…”
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Microbial metabolic noise by Vasdekis, Andreas E., Singh, Abhyudai

“…From the time a cell was first placed under the microscope, it became apparent that identifying two clonal cells that “look” identical is extremely…”
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Video-rate Raman-based metabolic imaging by Airy light-sheet illumination and photon-sparse detection by Dunn, Lochlann, Luo, Haokun, Subedi, Nava R, Kasu, Ramachandran, McDonald, Armando G, Christodoulides, Demetrios N, Vasdekis, Andreas E

“…Despite its massive potential, Raman imaging represents just a modest fraction of all research and clinical microscopy to date. This is due to the ultralow…”
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Precision Intracellular Delivery Based on Optofluidic Polymersome Rupture by Vasdekis, Andreas E, Scott, Evan A, O’Neil, Conlin P, Psaltis, Demetri, Hubbell, Jeffrey. A

“…We present an optical approach for intracellular delivery of molecules contained within oxidation-sensitive polymersomes. The photosensitizer ethyl eosin is…”
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Photon-Sparse, Poisson Light-Sheet Microscopy by Sanchez, Tristin, Subedi, Nava R, Thompson, Cole, Sheneman, Luke, Vasdekis, Andreas E

“…Light-sheet microscopy has revolutionized bioimaging by enabling approximately an order of magnitude reduction in specimen irradiance compared to confocal…”
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Optofluidic evanescent dye laser based on a distributed feedback circular grating by Song, Wuzhou, Vasdekis, Andreas E., Li, Zhenyu, Psaltis, Demetri

“…We demonstrate an optofluidic evanescent laser based on a solid circular distributed feedback grating with the dye solution acting as the cladding layer. The…”
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An unexpected phase transformation of ceria nanoparticles in aqueous media by Kuchibhatla, Satyanarayana V.N.T., Karakoti, Ajay S., Vasdekis, Andreas E., Windisch, Charles F., Seal, Sudipta, Thevuthasan, Suntharampillai, Baer, Donald R.

“…Cerium oxide nanoparticles (CNPs) are of significant interest to the scientific community due to their widespread applications in a variety of fields. It is…”
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Mesoscale Polymer Dissolution Probed by Raman Spectroscopy and Molecular Simulations by Chang, Tsun-Mei, Xantheas, Sotiris S

“…The diffusion of various solvents into a polystyrene (PS) matrix was probed experimentally by monitoring the temporal profiles of the Raman spectra and…”
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Modular polymer biosensors by solvent immersion imprint lithography by Moore, Jayven S., Xantheas, Sotiris S., Grate, Jay W., Wietsma, Thomas W., Gratton, Enrico, Vasdekis, Andreas E.

“…ABSTRACT We recently demonstrated Solvent Immersion Imprint Lithography (SIIL), a rapid benchtop microsystem prototyping technique, including polymer…”
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